Pluchino lab - Regenerative Neuroimmunology @Pluchinolab
Developing experimental molecular medicines for chronic inflammatory diseases of the brain. 🇬🇧🇺🇸🇮🇹🇫🇷🇿🇦🇭🇰🇺🇦 🦋 Bluesky @pluchinolab.bsky.social pluchinolab.org Cambridge, UK Joined September 2011-
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Pluchino lab - Regenerative Neuroimmunology retweeted
"Neurotech: Developing Brainy Ideas Through Clever Design" 🗓️ 15 September 📍 Cambridge This inspiring early evening of thought-provoking discussions will feature a fireside chat with our Director, Sir Tony Kouzarides and Jason Mellad. 🔗 ow.ly/UvNH50WP0mS
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Pluchino lab - Regenerative Neuroimmunology retweeted
🧠 How do brain phagocytes shape neuronal life and death? Find out with Francesca Peri @UZH_en in her seminar at HT on #microglia and their role in clearing dying neurons. Register by 1 Oct 👉 humantechnopole.it/en/training/ex…
Single-cell transcriptomic and genomic changes in the ageing human brain | Nature nature.com/articles/s4158…
Brain-wide representations of prior information in mouse decision-making | Nature nature.com/articles/s4158…
A brain-wide map of neural activity during complex behaviour | Nature nature.com/articles/s4158…
Pluchino lab - Regenerative Neuroimmunology retweeted
realtalkms.com/418 Last week, the UAE became the first country in the world to approve Tolebrutinib for adults with non-relapsing secondary progressive MS. Tolebrutinib represents a new category of disease-modifying therapy that has people excited. We're talking about why.…
Whole-genome single-cell multimodal history tracing to reveal cell identity transition biorxiv.org/content/10.110…
Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action | Journal of Experimental Medicine | Rockefeller University Press hubs.la/Q03GtbGx0
Cytosolic DNA crosstalk in senescence: a new axis of inflammatory signaling? embopress.org/doi/full/10.10…
Metformin alters mitochondria-related metabolism and enhances human oligodendrocyte function nature.com/articles/s4146…
Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits science.org/doi/10.1126/sc…
Proinflammatory Effect of Mesenchymal Stem Cells From Patients With Multiple Sclerosis neurology.org/doi/pdfdirect/…
Mitochondria structurally remodel near synapses to fuel the sustained energy demands of plasticity biorxiv.org/content/10.110…
Follicular regulatory T cells promote experimental autoimmune encephalomyelitis by supporting B cell egress from germinal centers science.org/doi/10.1126/sc…
Pluchino lab - Regenerative Neuroimmunology retweeted
Some mitochondria puff out their content into the cytoplasm, exhibiting localized membrane distentions. This may contribute to inflammatory responses, for examples.
Understanding monocyte-driven neuroinflammation in Alzheimer’s disease using human cortical organoid microphysiological systems science.org/doi/10.1126/sc…
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