Intestinal Cell News @Intestinal_Cell
An online resource for intestinal cell researchers. Part of the @STEMCELLTech Science News service. intestinalcellnews.com Joined October 2012-
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😯💨 Researchers assessed the diagnostic potential of volatile organic compounds in exhaled breath via an electronic nose for noninvasive CRC detection. Check it out!👉 bit.ly/3V1UZZU
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📊 Dr. Alice Day (@Alice_APD) and researchers at @TQEHofficial performed a deep functional analysis of the feces of 28 adults with mild-moderately active #UlcerativeColitis who adhered to the 4-SURE diet over 8 weeks. 🔗 bit.ly/3I6Uyuf
📢 Integrated multi-omics analyses revealed that ACTL6A deficiency alters chromatin accessibility and upregulates p53 pathway-related genes, accompanied by the recruitment of SWI/SNF and INO80 complexes. @cddpress | go.nature.com/4na1RjS
Intestinal Cell News retweeted
FGFR1-amplified colorectal cancer: a distinct prognostic subtype identified through integrated genomic and IHC profiling in @ESMO_Open. CRC FGFR profiling (n=7,606) spots aggressive FGFR1-amp tumors. Possible screening by novel IRS IHC method. esmoopen.com/article/S2059-…
Intestinal Cell News retweeted
The annual colorectal cancer incidence among US adults aged 45 to 49 surged by 12% from 2019 to 2022, likely due to earlier detection following lowered screening age recommendations. ja.ma/4p0n2X4
Researchers with Dr. Jan Willem Thuring and Fabian Hulpia describe their efforts, challenges, and compound evaluation workflow resulting in gut-restricted PRMT5 inhibitors. 💊 bit.ly/3USa3ZT
New in @cddpress! 💡 Integrated multi-omics analyses revealed that ACTL6A deficiency alters chromatin accessibility and upregulates #p53 pathway-related genes, accompanied by the recruitment of SWI/SNF and INO80 complexes. 🧬 Get the full story: go.nature.com/4na1RjS
Researchers with Dr. Lixia Yang explored the role of GDF15 in regulating ferroptosis through the p62/Keap1/Nrf2 pathway and to elucidate its impact on #GastricCancer progression. 🖱️ Click here to read the study: bit.ly/47ctTqg
Researchers with Dr. Liyu Huang constructed mouse gastric #organoids to recapitulate the morphological and functional characteristics of diffuse-type #GastricCancer for @US_FDA-approved drug screening. 📝 Read their findings in @BrJCancer! 🔗 go.nature.com/41WKKcY
In #CRC, m5C modification affects cell proliferation, migration, invasion, drug resistance, and #immunotherapy resistance by regulating RNA stability, metabolic reprogramming, signaling pathway activation, and immune escape. 🔓 Read the review: bit.ly/3UERuIH
Here's latest in #GastricCancer (GC) research! ✍️ Silencing GDF15 inhibits the p62/Keap1/Nrf2 pathway, promoting ferroptosis and suppressing GC progression. 🔗 Read the study: bit.ly/47ctTqg
🔬 Scientists with Dr. Kim Lucia Schneider at @yourUMG reveal that Mif depletion in epithelial tumor cells attenuates cancer maintenance in both CRC models, coinciding with reduced macrophage recruitment and angiogenesis. 🔗 go.nature.com/4mYskRs
Intestinal Cell News retweeted
According to a study co-led by researchers at MSK and published in @NatureMedicine, a new vaccine shows encouraging early results as a potential ready-made treatment for patients with pancreatic or colorectal cancer. Unlike individualized cancer vaccines, which are tailored to…
🧬 Dr. Yuan-Hung Lo and team at @MDAndersonNews show that large-scale CRISPR-based genetic screens can be applied in primary human 3D gastric #organoids to identify genes that affect sensitivity to cisplatin. @NatureComms | go.nature.com/3HABHaU
🎯 The authors evaluate the value of G protein-coupled receptors (GPCRs) as diagnostic indicators and therapeutic targets, summarize current GPCR-targeted strategies, and propose future research to advance the diagnosis and management of gastric cancer. 🔗…
🧬 Data from TCGA and GEO datasets revealed significant upregulation of UBE2C in gastric cancer tissues, with a negative correlation between UBE2C and ACSL4, a key regulator of ferroptosis. 🔗 bit.ly/45B3hww
Scientists share the results of a Phase Ib/II study investigating the efficacy and safety of combining PD-1 antibody with chemotherapy and vascular endothelial growth factor antibody in locally advanced dMMR/MSI CRC. 🩺 bit.ly/45iJxPq
Scientists performed integrative multiomics analysis to reveal the subtypes and key mechanisms of platinum resistance in #GastricCancer. They identified KLF9 as a promising therapeutic target. 🎯 bit.ly/4ltgYUf
✍️ Dr. Andrew Chan and colleagues synthesizes evidence on the relationship of obesity and T2DM with early-onset CRC, focusing on pathophysiological mechanisms and the mediating roles of diet and lifestyle factors. @NatureRevEndo | go.nature.com/3HwIu5d
Scientists identified EPS8L2 as a significantly upregulated gene in #ColorectalCancer tumor tissues, where it exhibits oncogenic properties. 🔓 More in @cddpress: go.nature.com/4muTCPz
Organoid News @organoidscience
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מיכאל איצקו... @tjbt60RUdqvR0pJ
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CHOI LAB @The_Choi_Lab
313 Followers 92 Following Gastric carcinogenesis / Stem cells / Transgenic mouse models / Organoid models
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783 Followers 1K Following General and Digestive Surgery. Colorectal. H.U.Torrecardernas
Heather McCauley @_HAMcCauley
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49 Followers 164 Following PhD student in the Sonnen lab, @_hubrecht | signalling dynamics in intestinal organoids
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198 Followers 355 Following We are a mucosal immunology lab with expertise in colon cancer, inflammatory bowel disease, microbiome and neuroinflammation.
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271 Followers 177 Following Basic/Translational Researcher & Gastroenterologist at Wash U in St. Louis. Studying subcellular processes involved in metaplasia and cancer.
Andreanna Burman @AndreannaBurman
500 Followers 808 Following @VanderbiltCDB PhD Candidate Studying Intestinal Disease @GoldenringLab & @iKajiLab 🔬| @NSF GRFP Fellow
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164 Followers 107 Following
Mike Nikolaev @mike_nikolaev
407 Followers 301 Following Scientist @Roche @IHB_Research, Alumni @TheLutolfLab, @EPFL Organoids bioengineering & microfabrication 👨🔬🧗🏔⛷
Dedrick Chan 曾国�... @dedrickchan
389 Followers 492 Following Academic Colorectal Surgeon 💩, Clinician-Scientist 🧬 | Studying cancer initiation and evolution 🤼♂️ | Crossing dimensions from a dot 🇸🇬 to a globe 🌏
Matthias Lutolf @TheLutolfLab
6K Followers 365 Following Institute of Human Biology (IHB), Roche, Basel, Switzerland. Institute of Bioengineering, EPFL, Switzerland. #organoids, #tumoroids, #stemcells, #bioengineering
Olga Mitrofanova @olga_mitrofan
183 Followers 88 Following Postdoctoral Scientist with @TheLutolfLab at @IHB_Research @Roche Bioengineering advanced in vitro models of gastrointestinal tract transforming drug discovery
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65 Followers 115 Following Postdoctoral Scientist working on human intestinal organoids and IBD. Interested in molecular medicine and innovative therapeutic approaches
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162 Followers 314 Following PhD student at @FricLab @FNUSA_ICRC. Focused on #organoids #IBD #crohnsdisease #MAITcells #inflammation
Saranyaraajan Varadar... @saranya_raajan
181 Followers 254 Following Postdoc @PandALab_UofM | PhD from Miller lab @UMich | Interested in epithelial barrier function | AHA Pre-doctoral fellow | Immigrant
Evangelos Giampazolia... @giampazolias
1K Followers 1K Following Group Leader, Cancer Immunosurveillance Lab @CRUK_MI. Interested in how #HostMicrobiome interactions and #CellDeath dictate #CancerImmunity.
Elias Orouji @orouji
2K Followers 2K Following Epigenomics Lead at Princess Margaret Cancer Centre @pmcancercentre @uhn | University of Texas MD Anderson Cancer Center @MDAndersonNews | DKFZ @dkfz alumnus
Sarah Dooley @ScientistSarah_
210 Followers 140 Following
Clara L. Salazar @clarasalazarg
262 Followers 930 Following MSc. PhD. Microbiología Clínica- Microbiota intestinal,Bacterias Anaerobias y C.difficile 🔬🧬🧪
Mahya @MahyaBondar
147 Followers 314 Following 🤓👩🏻🔬🧬🧫🔬 🌱☕🎶🎬📸📚📝INTP, PhD candidate, Investigating the role of gut in Parkinson’s disease 🧠🧐
James Cleary @JamesClearyMD
2K Followers 822 Following Gastrointestinal Oncologist at @DanaFarber and @Harvardmed. Aspiring runner. @EinsteinMed, @RutgersU, and @StBenedictsNJ grad.
Gastrointestinal and ... @OGIPclinic
574 Followers 114 Following Gastrointestinal and Pancreatic translational oncology research at @idibaps @hospitalclinic @ciberehd. Focus on Genetics, Epigenetics, Gene Therapy, Endoscopy
Eoghan J Mulholland �... @EJ_Mulholland
826 Followers 533 Following Lee Placito Fellow of Gastrointestinal Cancer 👨🏻🎓 @UniofOxford 👨🏼🔬🎓 Oncology🔬 Precision Medicine 🧬 All genes expressed are my Eoghan
Pukkila-Worley Lab is... @RPWLab
685 Followers 158 Following Research Scientist. Infectious Diseases Physician. Professor of Medicine. UMass Chan Medical School. Innate immunity, intestinal epithelial cells and worms.
Britt Christensen, MB... @IBDmedicaldoc
798 Followers 295 Following Mother of 4! Head IBD, Royal Melbourne Hospital. Assoc Professor, Uni Melb. Gastroenterologist specialising in IBD and intestinal ultrasound. Tweets r my own.Trends for United States
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