Param P Singh @param_p_singh
Assistant Professor @UCSF, @UCSFAging studying aging, diapause and evolution using killifish and computational biology. SinghLabUCSF.org San Francisco, CA Joined December 2014-
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Param P Singh retweeted
Beyond thrilled to share 3 papers on the killifish from our lab and fantastic collaborators!! 🐟🙌 Two on protein aggregates during aging – with @JaroszLab! cell.com/developmental-… cell.com/cell-reports/f… One on evolution of 'suspended animation'! cell.com/cell/fulltext/…
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I'm excited to share our study on the evolution and regulation of diapause in killifish, out today @CellCellPress! Thank you to all the co-authors and collaborators! 🙏 @BrunetLab @SnyderShot @ChiKuoHimself @KPapsdorf @JayJWM50 @KContrepois, Adam Reeves! cell.com/cell/fulltext/…
Param P Singh retweeted
Incredibly excited to share our paper on the impact of partial reprogramming on neurogenic niches of the old brain (in mice)!! Massive congratulations to first-author Lucy Xu and all the authors!! 🌟🙌🍾 nature.com/articles/s4358…
Param P Singh retweeted
A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan biorxiv.org/content/10.110…
Param P Singh retweeted
Stunning talk from @JD_Buenrostro at #singlecellgenomicsday, highlighting how to squeeze TF footprinting insights out of scATAC-seq data, and identifying transcription factors that drive HSC aging.
Stunning talk from @JD_Buenrostro at #singlecellgenomicsday, highlighting how to squeeze TF footprinting insights out of scATAC-seq data, and identifying transcription factors that drive HSC aging.
Param P Singh retweeted
Very cool - rejuvenation of the immune system! nature.com/articles/s4158…
Param P Singh retweeted
What Alzheimer noted as fat saccules in glia may have been lipid droplets. They can be induced by Abeta in microglia leading them to release factors that damage neurons. ApoE4 makes things worse rdcu.be/dA6Kh. Congrats @Michael_S_Haney @robipalo and fantastic team
Param P Singh retweeted
We are hiring TWO research assistants to join the lab. 1)Molecular biology of aging postdocs.yale.edu/postgraduate-p… and 2)lipid biology and mass spectrometry postdocs.yale.edu/postgraduate-p… Interested in aging, stem cells, lipids and mass spec? Please reach out!☺️
Param P Singh retweeted
Postdoctoral fellow to study aging and diapause in the African killifish @param_p_singh Postdoc position in the Singh Lab at UCSF to study aging, age-related diseases, and diapause using multi-omics in the African killifish. jobrxiv.org/job/singh-lab-… #... jobrxiv.org/job/singh-lab-…
Param P Singh retweeted
Param P Singh retweeted
Check out the table of content for the collection of African killifish protocols!! 🐠🐟 We welcome new protocols from the killifish community! If submitted soon they can be part of this table of content. Contact me! cshprotocols.cshlp.org/site/misc/manu…
Param P Singh retweeted
A long time ago, @ElementoLab and I came up with our solution to the gene-set enrichment analysis. We used mutual information to measure the association between gene-set membership and input. After a decade, a talented undergrad spearheaded an update: biorxiv.org/content/10.110…
Killifish lab manual with a collection of latest protocols, edited by @BrunetLab
Killifish lab manual with a collection of latest protocols, edited by @BrunetLab
Param P Singh retweeted
Incredibly excited to share our paper on chromatin changes in neural stem cells during aging It revealed defects in cell migration with age! CONGRATS to @robinwyeo and @OliviaYZhou! Awesome collaboration with @anshulkundaje and @Dunn_Lab! 🎉🥂 nature.com/articles/s4358…
Param P Singh retweeted
Exciting opportunity for a bioinformatician and a fly postdoc in our lab to study eye aging and neurodegeneration. Please share if you know anyone who would be interested in applying. Thanks
Exciting opportunity for a bioinformatician and a fly postdoc in our lab to study eye aging and neurodegeneration. Please share if you know anyone who would be interested in applying. Thanks
Param P Singh retweeted
Online now! New review in @trendscancer on MiT/TFE transcription factors, lysosomes and cancer with @RobertoZoncu. We highlight emerging modes of MiT/TFE regulation and activity in cancer. Free online for 50d at this link: authors.elsevier.com/a/1hLMI8Z12yTu…
Param P Singh retweeted
Perspective co-authored with @param_p_singh out today in @NatureAging, where we outline best practices in "omics" for #aging research. We outline biological and technical considerations key to #reproducible results. rdcu.be/dfGsi
Our perspective with @BBParis1984 on best practices for omics experiments in aging research is out in @NatureAging We hope this is useful for the aging community and beyond. nature.com/articles/s4358… @UCSF @UCSFAging
Param P Singh retweeted
Grateful to partner with @JswLab on a project led by @Richard_She and @TylerFair_ exploring the extent and identity of human-specific genetic dependencies sciencedirect.com/science/articl…
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