pylelab @pylelab
RNA Biology, RNA tertiary structures, viral RNA, and RNA-protein machines. Based at @MCDB_Yale. All opinions and RTs are our own. pylelab.org New Haven, CT Joined April 2021-
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pylelab retweeted
📢ONLINE event this month! ⏲️5pm GMT, 14th Dec 2023, next Thursday! This month we happily invite Danny and Ling to show their exciting RNA structural stories! Please register our mail list for zoom link🥳 Many thanks to our sponsors @RNASociety @lexogen
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pylelab retweeted
“Incredibly dynamic” #RNA: Anna Marie Pyle’s group @pylelab sheds light on how a section of bacterial RNA catalyzes a reaction that frees it from its parent strand. This ancient splicing method still closely resembles that employed in human cells. 🔗 hhmi.news/3uCAuJb
pylelab retweeted
Nature research paper: Structural insights into intron catalysis and dynamics during splicing go.nature.com/3QTKPYL
A recent paper from the Pyle Lab discusses the use of MRT-ModSeq for the detection of RNA modifications using 2D mutational profiles. Read more here: sciencedirect.com/science/articl…
pylelab retweeted
Can #RNA recognize small compounds specifically? Can the #splicing core be targeted by #smallmolecules? Exciting answers in our new preprint on the molecular mechanism of splicing inhibition by intronistat b biorxiv.org/content/10.110… @EMBLGrenoble @IITalk @devivo_marco
pylelab retweeted
Principles of #lncRNA structure-functional connections emerging! Our new work in press shows how lncRNAs use non-canonical #GUwobble motifs to shape their molecular structure and define their function doi.org/10.1016/j.bioc… @EMBLGrenoble @KariSabalette @epifiz87 @elsbiochimie
Congratulations to all the GRC 2023 Nucleic Acids poster award winners! The poster sessions were one of the highlights of the conference! If you’re thinking about applying for the 2025 GRC, we definitely encourage presenting a poster about your ongoing science! #grcnucleicacids
The GRS Nucleic Acids was also a great success! Thank you Mano and @KrishnanYamuna for spending time with the trainees and ECRs!
The GRS Nucleic Acids was also a great success! Thank you Mano and @KrishnanYamuna for spending time with the trainees and ECRs!
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