Reuben Philip @reuben_phi
PhD Candidate @PelletierLab, @SinaiHealth, @UofT 🍁 Advanced Imaging 🔬 | Genome Engineering ✂️ I like to light cells up and watch em dance Toronto, Canada Joined July 2017-
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When the PI hasn't worked in at the bench in years but needs to do something in the lab for a photoshoot
Automated optogenetic control of hundreds of cells in parallel. Each cell is individually steered, collectively acting as a "tissue printer". Preprint & code out!
The brain is the master regulator of food intake and energy balance. A brilliant new @CellCellPress review, including the mechanism of GLP-1 drugs, by @ClemmensenC and colleagues, open-access cell.com/cell/fulltext/…
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,…
63 biliary cancer cell lines!! An unbelievable resource from the Bardeesy Lab @MGHCancerCenter
63 biliary cancer cell lines!! An unbelievable resource from the Bardeesy Lab @MGHCancerCenter
Excited to share our pre-print on the molecular architecture of heterochromatin in human cells🧬🔬 w/ @jpkreysing, Johannes Betz,Turoňová lab, @MarinaLusic, Hummer lab, @Beck_Laboratory, @MPIbp 🔗 Preprint here: doi.org/10.1101/2025.0…
Today we report in @NatureMedicine the development of a base editing strategy for prion disease, currently a fatal and rapidly progressing neurogenerative condition with no effective treatment. @prionalliance @DevermanLab (1/13) drive.google.com/file/d/1DVpKrz…
Ready for the most powerful foundation model for medical images/videos? 🚨 Just dropped: MedSAM2 The next-gen foundation model for 3D medical image & video segmentation — built on top of SAM 2.1. • Project site: medsam2.github.io • Paper: arxiv.org/abs/2504.03600 Why…
Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome🧵 @NatureMedicine
Our live imaging video of muscle cell fusion is hosted on HHMI's Beautiful Biology! Thanks BB for selecting our video and congratulations to @YueluUTSW! hhmi.org/beautifulbiolo…
Do you LOVE organelles?? Well I am THRILLED to announce that Nellie has been published in @naturemethods! Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy 🧵1/N
Five years of work, one big question: Which has a greater impact on aging—our environment or our genes? I'm excited to share our paper published today in Nature Medicine, demonstrating the major role of the #exposome in shaping mortality and #aging. nature.com/articles/s4159…
Two absolutely fantastic bioimage analysis papers out today offering exceptional, generalizable tools for segmentation--Cellpose3 and Segment Anything for Microscopy. (1/3)
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). @IBECBarcelona
That’s my Canada. Peaceful, trustworthy, supportive, world-class excellence. I stand on guard for thee.
📢Excited to introduce NanoCas -our new mini CRISPR system that can reach tissues previously out of reach! By shrinking CRISPR to 1/3 its normal size, we can now edit genes in muscle, heart & brain that were difficult to access before. Summary & link to paper:
Explore our tagging tools from the @PelletierLab! They feature cassettes with mStayGold for bright and photostable endogenous fusions. Now available on @Addgene: addgene.org/Laurence_Pelle…. Check out the paper in @embojournal: embopress.org/doi/full/10.10… #FluorescenceFriday
Did you know that Sinai Health’s Network Biology Collaborative Centre has the latest microscopy instruments, software & state-of-the-art expertise available to researchers from any institution? Find out how you too can advance your research 👉 bit.ly/4fzgXM9

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149 Followers 272 Following @imgprague research group studying cytoskeleton organization in cell and tissue mechanics. Tweets by Martin Gregor & lab members. Also on https://t.co/yzQ0N1XjZD
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Robin @machomunthe_LFC
120 Followers 2K Following PhD student in physics, Clemson University. #LFC #YNWA
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560 Followers 1K Following Postdoctoral Fellow | STRAIGHT-IN Dual platform | @GallowaylabMIT | @MIT | Mammalian Synthetic Biology | Stem Cell Biology | Forward Programming |
Richard Kollen @nuclearball
2K Followers 3K Following Johns Hopkins Univ., NASA, ESA, DFVLR, & SKYNET. Here for MEDICAL. I RT Doc jobs.
Kouki Kawakami @kk_kawakami
451 Followers 443 Following HEKato Lab (JSPS-PD, UTokyo) ← Asuka Inoue Lab (Tohoku Univ.) / GPCR
Rishi Puram @rishi_puram
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794 Followers 412 Following Prof @UofT | Nuclear/genome organization and stability | RNA-DNA | Ribosomes | Cancer & aging | Basic to translational research | Now also on https://t.co/ZxEI29Xqcn
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Governor Newsom Press... @GovPressOffice
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39K Followers 2K Following - CEO https://t.co/wb4ZDbN2SX / Neoliberal / @playrust lover - Creating web experiences educating about antisemitism - §230/Privacy/Comedy - https://t.co/gciawObgu7
NewsWire @NewsWire_US
104K Followers 212 Following U.S. and world news aggregator. Turn on notifications. Powered by @Polymarket. Bet on politics, elections and more: https://t.co/1n3rw5OCCU
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