Dr. Dinesh Khanna @sclerodermaUM
👉University of Michigan Scleroderma Program leading the way through excellence in clinical care, teaching, & research #scleroderma tweets≠advice Follow≠endorse medicine.umich.edu/dept/intmed/di… Ann Arbor, MI Joined July 2017-
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Dr. Dinesh Khanna retweeted
Join us today at 12 pm for Grand Rounds on "Systemic Sclerosis: An Update" presented by @sclerodermaUM, professor in the Division of Rheumatology. Learn more: medschool.umich.edu/departments/in…
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Delighted to present @UMIntMed grand rounds today at noon ET. Systemic Sclerosis- an update! Join at umich.zoom.us/j/97732438261 Password: 606879
Dr. Dinesh Khanna retweeted
DID YOU KNOW? >30% of Systemic Sclerosis pts present without Raynauds!. Data from 2 large US cohorts, of SSc dx with puffy fingers/hands or other symptoms. Such patients presented with more severe skin and musculoskeletal disease. buff.ly/t6mFdB9
Our first person Susan Chrysogelos who received CAR-T #scleroderma @UMIntMed @srfcure @scleroderma michiganmedicine.org/health-lab/scl… #findcureforscleroderma
Dr. Dinesh Khanna retweeted
Bringing rheumatology closer to haematology. CAR-T therapy is showing tremendous promise in autoimmune conditions esp difficult to treat cases. #eular2025
Bringing rheumatology closer to haematology. CAR-T therapy is showing tremendous promise in autoimmune conditions esp difficult to treat cases. #eular2025
“Normal” CPK by race and gender. @docrota @FloridaRheums
Great lecture by Dr Seo. Summary slide on ANCA vasculitis @FloridaRheums
Dr. Dinesh Khanna retweeted
Novel Rx for #scleroderma ?adaptive ?B cells ?Tcells ?anti inflammatory ?costimulatory ?interferon ⬇️ ?anti fibrotic ?vascular remodelling 🤔all of above Hope for #SSc @Worldsclerofnd @SclerodermaCAN @scleroderma_sso @SclerodermaNews @sclerodermaUM @FloridaRheums #FSR2025
Dr. Dinesh Khanna retweeted
#CAR-T in active #scleroderma #diffuse open label @sclerodermaUM presented improvement in #nailfold #capillary patterns Suggesting #vascular recovery Hope is for lungs, skin and survival to improve but These are ▶️ Early days ?risk OP0338 #EULAR2025. @RheumNow @eular_org
Dr. Dinesh Khanna retweeted
🚨 Promising advances in #SystemicSclerosis at #EULAR2025! 🧬 CD19 CAR-T therapy shows encouraging efficacy in SLE, SSc & IIM with manageable safety ⚠️ 🔬 11+ ongoing Phase 2/3 trials in SSc(-ILD) targeting fibrosis, immunity, vasculopathy @sclerodermaUM
Considering Phase 3 trial in #scleroderma? if thinking about individual organ, consider this work presented at the #EULAR2025 and supported by SCTC and @NIH_NIAMS For composite endpoint, revised CRISS is being qualified by the regulatory agency
Excited to present data from RESET-SSc in #scleroderma #eular2025. CAR-T was well tolerated with beneficial effects on skin/ FVC. Exciting data on U-M IIS with LN bx showing complete depletion of B cells at 3 weeks and NFC showing normalization of capillary density and size
Excited to present WIN #scleroderma #eular2025. This slide highlights the opportunities in drug development in SSc. Come and join on Saturday 6/14 at 9 AM CET.
Work done by scleroderma program at @umichmedicine with @elizatsou and Johann Gudjonsson was licensed to Liferna Biotech! Exciting times to develop new therapies in #scleroderma and other fibrotic diseases! linkedin.com/feed/update/ur… liferna-biotech.com
Looking forward an exciting #eular2025. Exciting data on CAR-T in #scleroderma and invited lecture on WIN in systemic sclerosis. thanks for the invitation @eular_org
Advances and future outlook in clinical trials for treating systemic sclerosis-interstitial lung disease tandfonline.com/doi/full/10.10… Free copy available for download
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