Sreeram Maddipatla @sreeram08
Oncologist at Orlando Health Cancer Institute specializing in solid tumors and hematologic disorders. Tweets and opinions are my own. Joined September 2009-
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Followers386
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New report that CHIP (clonal hematopoiesis of indeterminate potential, blood stem cell clones that increase with age) is an independent risk factor for myocarditis and pericarditis, promoting inflammation #ESC2025 @JAMA_current jamanetwork.com/journals/jamac…
Rare pathogenic variants in 16 #cancer predisposition genes were linked to both single and multiple cancer diagnoses, suggesting multigene panel testing could be beneficial. ja.ma/4m8XcOl
💡 Lesson: The inverse of these 7 rules = how to deliver a brilliant Grand Rounds. 👉 Know your audience 👉 Stay clinically relevant 👉 Make complexity accessible Great talks don’t show how much you know— They ensure the audience leaves knowing something they didn’t before.…
Exciting science and clinical efficacy in this @MDAndersonNews team science study led by @VanMorrisMD In Cancer Cell. Triple therapy with IO led to durable responses in BRAF V600E MSS colorectal cancer, showing promise. Randomized study ongoing. #crcsm cell.com/cancer-cell/fu…
Elevated B12 serum levels are associated with the presence of clonal hematopoiesis ow.ly/I6kU50WIUtw #myeloidneoplasia #clonalhematopoiesis
The challenges of eliminating (the bad) senescent cells with multiple shots on goal nature.com/articles/s4358…
The early detection of pancreatic ductal adenocarcinoma may soon be realized, based on the accuracy of microRNA-based liquid biopsy assays, according to new research. clinicaloncology.com/a/BDABAA/t
The global burden of liver cancer is increasing, with new cases set to double by 2050. On the cover, the latest Commission report on addressing the global hepatocellular carcinoma burden. This and more in our latest issue 👉 hubs.li/Q03CWycG0
Cisplatin saves lives, but kidneys pay a price. 🔘1 in 7 pts develop Chronic Kidney Disease After Cisplatin Treatment. Baseline eGFR is the strongest predictor, check it, discuss risks, hydrate, avoid nephrotoxins. #Nephrology #Oncology @JAMAOnc @OncoAlert @OncBrothers @Uromigos…
Overall Survival with Neoadjuvant Nivolumab plus Chemotherapy in Lung Cancer @FordePatrick et al. nejm.org/doi/full/10.10…
Confidence is silent. Insecurity is loud.
1/ Meet Gaurav Trivedi, an Indian scammer who impersonates Microsoft support and then rips off innocent vulnerable people. He tried to scam me......but instead of paying him money, I hacked into his laptop and turned on his live webcam feed.
Newly diagnosed acute myeloid leukemia in unfit patients: 2026 treatment algorithms | Blood Cancer Journal nature.com/articles/s4140…
This is the table we’ve used (common AEs, black📦warnings, & dose⬇️) during our discussion for #Lenvatinib, #Cabozantinib, #Axitinib, #Tivozanib #Belzutifan in RCC w/ @montypal #OncTwitter #gusm #MedTwitter @OncoAlert @OncUpdates
This is the table we’ve used (common AEs, black📦warnings, & dose⬇️) during our discussion for #Lenvatinib, #Cabozantinib, #Axitinib, #Tivozanib #Belzutifan in RCC w/ @montypal #OncTwitter #gusm #MedTwitter @OncoAlert @OncUpdates https://t.co/pDWuLckacS
Colorectal Cancer Incidence in US Adults After Recommendations for Earlier Screening jamanetwork.com/journals/jama/… Among individuals aged 45 to 49 years, an increase of 1.1% annually during 2004-2019 accelerated to 12.0% annually during 2019-2022 @AskDrShashank @DrIanWeissman
Moderate benefit seen with nivolumab + ipilimumab in immunogenic signature–positive mCRPC, with response in ~32% of patients and variable durability. Study by @Gianmarco_LeonC & Mark D. Linch, MD, PhD. 🔗 ascopost.com/news/august-20… #mCRPC #prostatecancer #Immunotherapy
Gene therapy has long held promise for the treatment of Parkinson’s disease. In @TheLancetNeuro, authors explore clinical trials and technical advances in gene therapy for Parkinson's disease: hubs.li/Q03zZPW-0
Lower urinary tract symptoms are common among men and are usually caused by BPH, overactive bladder detrusor, or both. This Review summarizes the epidemiology, pathophysiology, diagnosis, and management of these symptoms. ja.ma/3HhxA3d
The EU approved belantamab mafodotin (Blenrep) combinations in R/R multiple myeloma, enhancing treatment options for relapsed multiple myeloma patients with promising efficacy and safety profiles. Read the full story: targetedonc.com/view/eu-approv…
JAMA Patient Page: What Is Prostate Cancer? @JAMA_current @OncoAlert @PCFnews @APCCC_Lugano #prostatecancer jamanetwork.com/journals/jama/…

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