Yongjin Yoo @yongjinyoo
Lab of Yongjin Yoo at Korea University, Exploring #stemcell & #microglia in health and disease. Tweets by Yongjin and lab members. yongjinyoolab.com 대한민국 서울 Joined August 2010-
Tweets143
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Followers178
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Following615
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Likes139
Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1 | Nature nature.com/articles/s4158…
Rationale and Emerging Evidence for Microglial Replacement in Alzheimer’s Disease sciencedirect.com/science/articl…
Exciting finding led by Dr. Bruce Yankner: Endogenous lithium is essential for brain health and its deficiency contributes to the onset and progression of Alzheimer’s disease, by activating GSK3β—leading to impaired Aβ clearance and synapse loss 🔗 doi.org/10.1038/s41586…
Therapeutic genetic restoration through allogeneic brain microglia replacement | Nature nature.com/articles/s4158…
Nature research paper: Programmable protein ligation on cell surfaces go.nature.com/40HmcEs
Using newly developed mouse models and a microglia replacement strategy, researchers in Science show that bone marrow transplantation could be used as an effective therapy for ALSP, a rare and fatal neurodegenerative disease. 📄: scim.ag/4kW4jsR #SciencePerspective:…
Using newly developed mouse models and a microglia replacement strategy, researchers in Science show that bone marrow transplantation could be used as an effective therapy for ALSP, a rare and fatal neurodegenerative disease. 📄: scim.ag/4kW4jsR #SciencePerspective:…
Excitatory-neuron-derived interleukin-34 supports cortical developmental microglia function: Immunity cell.com/immunity/fullt…
Our new study by @DuSiling reveals how CSF1R mutations in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) disrupt glial homeostasis. Key roles for oligodendrocytes, astrocytes & STAT3 signaling. nature.com/articles/s4159…
Glymphatics and meningeal lymphatics unlock the brain-immune code: Immunity cell.com/cell-reports-s…
GABA-dependent microglial elimination of inhibitory synapses underlies neuronal hyperexcitability in epilepsy | Nature Neuroscience nature.com/articles/s4159…
Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease: Immunity cell.com/immunity/fullt…
Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia | Acta Neuropathologica link.springer.com/article/10.100…
Congrats to the authors @Yale on this exciting and important work! #BrainTCellsRule || The subfornical organ is a nucleus for gut-derived T cells that regulate behaviour | Nature nature.com/articles/s4158…
Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines: Cell Stem Cell cell.com/cell-stem-cell…
It was fun to learn about blood vessel organoids together with @freerangemarina and @TreutleinLab! Thanks to Reiner Wimmer and @penningerlab for introducing us to this system! cell.com/cell/fulltext/…. Great support from editors and reviewers @CellCellPress!
Thrilled to share our review just published in @NeuroCellPress! Big shoutout to Ava, Mengmeng , and our entire team! authors.elsevier.com/a/1k-uh3BtfHC%…
Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins: Cell Stem Cell cell.com/cell-stem-cell…
Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration: Neuron cell.com/neuron/fulltex…
🧠Have you ever cried when your #iPSC transgene vanished after differentiation? Yeah, we’ve cried too, and built a solution. Our PiggyBac vector keeps expression stable even after differentiation! Check out our #preprint👇 🔗 biorxiv.org/content/10.110… Supported by @cziscience

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ALSPInfo @AlspInfo
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NIH Funding @NIHFunding
55K Followers 34 Following Official account on NIH grants and funding information: funding opportunities, policy news, & more. https://t.co/mt3gbuKOjg Engagement ≠ endorsement
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