Aldo A. Rodríguez-Menchana @AARM_Lab
Ion channel research Joined June 2020-
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The case for lotteries as a tiebreaker of quality in research funding nature.com/articles/d4158…
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Aldo A. Rodríguez-Menchana retweeted
BREAKING NEWS: The 2021 #NobelPrize in Physiology or Medicine has been awarded jointly to David Julius and Ardem Patapoutian “for their discoveries of receptors for temperature and touch.”
Aldo A. Rodríguez-Menchana retweeted
A choreographed dance within the outer pore of Shaker dilating the filter during slow inactivation. Structure of the Shaker Kv channel and mechanism of slow C-type inactivation biorxiv.org/content/10.110…
Aldo A. Rodríguez-Menchana retweeted
Some interesting preprints on ion channel proteins! #Sciey #open science sciety.org/users/kenton_s…
Aldo A. Rodríguez-Menchana retweeted
Ion channels: A Collection of Articles elifesciences.org/collections/a4…
Aldo A. Rodríguez-Menchana retweeted
Harley Kurata discusses Marmolejo-Murillo et al's surprising report of polyamine-independent gating of Kir4.1/Kir5.1 heteromeric channels (bit.ly/3boWdbh), suggesting a mechanism of voltage dependence arising from interactions w/ permeating ions bit.ly/3xQhtzX
Aldo A. Rodríguez-Menchana retweeted
Unconventional voltage sensing in an inwardly rectifying potassium channel. Harley T. Kurata @UAlberta_FoMD discusses work (bit.ly/3boWdbh) by Marmolejo-Murillo and colleagues: bit.ly/3xQhtzX
Aldo A. Rodríguez-Menchana retweeted
Harley T. Kurata @UAlberta_FoMD discusses recent findings (bit.ly/3boWdbh) by Marmolejo-Murillo and colleagues that suggest a mechanism of voltage dependence in inwardly rectifying potassium channels arising from interactions with permeating ions. bit.ly/3xQhtzX
Aldo A. Rodríguez-Menchana retweeted
In @JGenPhysiol, Marmolejo-Murillo, Sánchez-Chapula, Rodríguez-Menchaca @UASLP_mx et al. identify a new intrinsic gating mechanism powered by the K+-flux in Kir4.1/Kir5.1 channels, which induces voltage-dependent inward rectification. bit.ly/3mj02mv #CellularPhysiology
Please take a look at our recent work
Please take a look at our recent work
Aldo A. Rodríguez-Menchana retweeted
Jongyun Myeong, Bertil Hille @UWMedicine et al. show that phosphoinositides subsequently regenerate during sustained receptor stimulation as a consequence of profound PI 4-kinase pathway acceleration and not desensitization of receptors. bit.ly/2UCneiF #Lipids #Membranes
Aldo A. Rodríguez-Menchana retweeted
Evaluating inositol phospholipid interactions with inward rectifier potassium channels and characterising their role in disease buff.ly/3kLsHPw from @CommsChem
Aldo A. Rodríguez-Menchana retweeted
Pip2 titration (0 mM - 1mM) on GIRK channels. Analysis reveals PIP2 shifts the equilibrium from extended to more compact state.While it depends on fraction of particles sorted and pooled from each conc., this is very nice study. Congratulations 🎉🎉 dx.doi.org/10.7554/eLife.…
Aldo A. Rodríguez-Menchana retweeted
In vitro and in silico characterization of the inhibition of Kir4.1 #ionchannels by aminoglycoside antibiotics buff.ly/2PVxKim
Aldo A. Rodríguez-Menchana retweeted
"As of this writing, the number of PIP2-modulated ion channels is approaching 100" pnas.org/content/early/…
Aldo A. Rodríguez-Menchana retweeted
Interfacial binding sites for Chol on Kir, Kv, K2P, and related K+ channels buff.ly/2OXs7Qc (@BiophysJ)
Aldo A. Rodríguez-Menchana retweeted
Roles of endogenous ether lipids and associated PUFAs in the regulation of ion channels and their relevance for disease buff.ly/32TAHb1 (@jlipidres)
Aldo A. Rodríguez-Menchana retweeted
Protein–lipid architecture of a cholinergic postsynaptic membrane scripts.iucr.org/cgi-bin/paper?…
Aldo A. Rodríguez-Menchana retweeted
The #SARSCoV2 envelope protein #insidecorona - only determined by NMR so far - plays an important role in the formation of new viruses. It may be a route to a vaccine against #Covid_19. Read more in Luise Kandler's excellent blog article: insidecorona.net/the-e-protein-…
Aldo A. Rodríguez-Menchana retweeted
Accessibility of cholesterol at cell surfaces buff.ly/2ZfVjH6 (@jlipidres)
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