ChristosArgyropoulos MD, PhD PharmanukerInChief @ChristosArgyrop
Division Chief, Nephrology UNMHSC (im)personal views & account #zerokale #nephrology #stats #coding #covid19isbad, #flozinator #glipinator, #MRAtor #pharmanuker Land of Enchantment Joined September 2011-
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my husband and I were running from a demon who was trying to kill us (in a video game) and I was about to die bc I couldn’t find a hiding spot but then my husband gave me his hiding spot and the demon killed him instead of me and I was like omg babe noo and then I looted his body
Interesting
Oh! "illustrate a fluther emerging from a kale bush acting very happy that avian flu and sarscov2 are best buddies and are going to school together in October"
There's never good time to stop collecting & reporting data. But in midst of nationwide outbreak of highly pathogenic H5N1 avian influenza in food supply animals and other mammals, all in close/constant interface with humans, seems to be one of the worst times to turn off the…
There's never good time to stop collecting & reporting data. But in midst of nationwide outbreak of highly pathogenic H5N1 avian influenza in food supply animals and other mammals, all in close/constant interface with humans, seems to be one of the worst times to turn off the…
@ChristosArgyrop @gianlucac1 @shay_fleishon @PeacockFlu @FabrizioChiodo @bronterDoc @FinchTH @james1chas3 Cybertruck ultra-light 😁
Excellent review of H5N1 for those who are interested sciencedirect.com/science/articl… one thing leave me astonished (though i dont know if virus swabbed is culturable or not) nevertheless ...80 fucking meters??? cc @shay_fleishon @PeacockFlu @FabrizioChiodo
@ChristosArgyrop Definitely not that either... why do people insist on making things unnecessarily hard 😕
@unclelobs @ChristosArgyrop M Y A N A C O N D A D O N T W A N T N O N E U N L E S S Y O U G O T B U N H O N.
@unclelobs @ChristosArgyrop @bunjavascript @t3dotgg Also JESUS FUCKING CHRIST THAT WAS A LOT OF WORK TO TYPE OUT.
@sc_codeUM - Sees tweet - Clicks profile - Clicks github profile - Repos: "typescript", "javascript", "python" - Closes github profile - Disregards opinion
@sc_codeUM Stop bashing bash scripts
@ChristosArgyrop There are methods that do this [e.g. SLIDE: pubmed.ncbi.nlm.nih.gov/19381255/] but practically the Pe'er et al. estimates of "effective" tests were actually pretty accurate and so p<5e-8 stuck (even when testing 5M or 10M common SNPs where Bonferroni would be more conservative)
@ChristosArgyrop Yes but it's complicated: - Bonferroni is just guaranteeing a false positive rate on the marginal association, it does not enforce anything about causal mechanism. - When variants are correlated (LD), Bonferroni will be conservative (but this is what Pe'er 2008 tried to quantify)
arstechnica.com/information-te… I own a refurbished HP with the same processor. AVX2 capable, monster of L1/2/3 caches.
It has been decades since I received a book in a wrap. This was the last copy of this gem of a #perl book
Verdict is in about spirullina
Farid Jalali, MD @farid__jalali
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my husband and I were running from a demon who was trying to kill us (in a video game) and I was about to die bc I couldn’t find a hiding spot but then my husband gave me his hiding spot and the demon killed him instead of me and I was like omg babe noo and then I looted his body
There's never good time to stop collecting & reporting data. But in midst of nationwide outbreak of highly pathogenic H5N1 avian influenza in food supply animals and other mammals, all in close/constant interface with humans, seems to be one of the worst times to turn off the…
We now enter the blackout phase of epidemiology: There will be patients, but their numbers and whereabouts will be unknown, with no central databases. Swell.
@ChristosArgyrop @gianlucac1 @shay_fleishon @PeacockFlu @FabrizioChiodo @bronterDoc @FinchTH @james1chas3 Cybertruck ultra-light 😁
@FinchTH @ChristosArgyrop @gianlucac1 @shay_fleishon @PeacockFlu @FabrizioChiodo @bronterDoc @james1chas3 Certainly droplet like, but Ferrari? 🤨
@gianlucac1 @ChristosArgyrop @shay_fleishon @PeacockFlu @FabrizioChiodo It’s 80 *MILD* meters.
Excellent review of H5N1 for those who are interested sciencedirect.com/science/articl… one thing leave me astonished (though i dont know if virus swabbed is culturable or not) nevertheless ...80 fucking meters??? cc @shay_fleishon @PeacockFlu @FabrizioChiodo
@ChristosArgyrop Definitely not that either... why do people insist on making things unnecessarily hard 😕
@ChristosArgyrop importing from R is that painful? I wonder if polars for R can leverage the same importing crate now.
@unclelobs @ChristosArgyrop M Y A N A C O N D A D O N T W A N T N O N E U N L E S S Y O U G O T B U N H O N.
@unclelobs @ChristosArgyrop @bunjavascript @t3dotgg Also JESUS FUCKING CHRIST THAT WAS A LOT OF WORK TO TYPE OUT.
@sc_codeUM - Sees tweet - Clicks profile - Clicks github profile - Repos: "typescript", "javascript", "python" - Closes github profile - Disregards opinion
@sc_codeUM Agreed. Shell scripts should be POSIX compliant whenever possible.
2: We still don’t have a complete understanding of population stratification, with many sub-threshold effects potentially overfitting to stratification [Aw et al. 2024]. The extent to which this impacts significant variants also remains unknown [Berg et al. 2019 eLife].
Ok, but this is twitter and we can't just talk about how great things have been. So here are four TRUTH BOMBS to absolutely DESTROY the GWAS die-hards out there (or at least lead to some interesting discussions instead of just rehashing the Bayesian/Frequentist food-fight).