Slava Epelman @EpelmanLab
Macrophages, DCs, virus, ischemia, hypertension, heterogeneity & the heart. Associate Prof, Univ of Toronto. UHN. Loretta Rogers Chair in Immunobioengineering epelmanlab.com Toronto, Ontario Joined October 2013-
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Slava Epelman retweeted
Through a huge multidisciplinary collaboration effort, we showed that fine particulate matter (PM2.5) exposure raises Lewy body dementia risk. Mechanistically, we found that PM2.5 exposure led to brain atrophy in mice. science.org/doi/10.1126/sc…
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Slava Epelman retweeted
New @ScienceMagazine A peptide released from white blood cells, directed against bacteria, can also poke holes in the membrane of heart muscle cells and induce a lethal arrhythmia (ventricular tachycardia). In the mouse model. science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…
Slava Epelman retweeted
Our new study in Science is out! CKD progresses slower in females. 🔹Estrogens boost female renal progenitors to produce new podocytes for pregnancy adaptation. 🔹Loss of this mechanism causes preeclampsia, maternal CKD risk & fewer nephrons in offspring. science.org/doi/10.1126/sc…
Slava Epelman retweeted
New concept & changes to peer review to make it faster and more friendly: 👇 Unleashing the Power of the Beehive to Begin a New Era for JACC: Basic to Translational Science jacc.org/doi/10.1016/j.… This only works if you, our readers, authors and referees, embrace it!!
Slava Epelman retweeted
Grateful to Dr. Jennifer Lippincott-Schwartz @JLS_Lab for her thoughtful Perspective article highlighting our work on ER–lysosome lipid transfer and lysosomal vacuolation. Honored to see our research placed in such a compelling context! science.org/doi/10.1126/sc…
Slava Epelman retweeted
Honored to be @ASIPath President. @umiamimedicine @univmiami @SylvesterCancer @UMiamiPathology Become a member 👇#pathobiology
Honored to be @ASIPath President. @umiamimedicine @univmiami @SylvesterCancer @UMiamiPathology Become a member 👇#pathobiology
Slava Epelman retweeted
Yale studied 682 people with long COVID or post vaccination syndrome. LC showed brain fog, smell loss, and breathlessness, while PVS showed burning sensations and neuropathy. Both may stem from spike protein immune responses but different pathways. medrxiv.org/content/10.110…
Slava Epelman retweeted
US study of over 12,000 military personnel found wearable devices detected persistent heart rate and HRV changes in 9.4% of COVID-positive cases, offering an objective way to spot potential Long COVID effects weeks after infection. nature.com/articles/s4159…
Job alert 🚨! If you are looking for a post-doc in cell engineering, macrophage biology, 🫀 regenerative medicine - we are hiring. Toronto is a great city to launch your career! jobs.smartrecruiters.com/UniversityHeal… @UHN_Research @StemCellNetwork @PMunkCardiacCtr @trogersresearch
Slava Epelman retweeted
Identifying a potential causal role of mitochondrial dysfunction in neurodegenerative disease, in multiple mouse models @NatureNeuro nature.com/articles/s4159…
Slava Epelman retweeted
Please join us for our 2nd Immuno-Cardiology Symposium in beautiful Bar Harbor, Maine, Sept. 18-19! @jacksonlab @MDIBL explore how dysregulated immune system function contributes to inflammation and fibrosis in disease and related disorders in the kidney, lung and liver
Slava Epelman retweeted
Led by @andrewhakeem, we reviewed the emerging evidence of organ crosstalk between the liver and heart during cardiometabolic disease. Key mechanisms include inflammation, liver-derived secretory factors, bone marrow reprogramming, and CHIP. @JACCJournals authors.elsevier.com/sd/article/S24…
Congrats @Homaira_H for winning best poster at #bcvs2025 @AHAScience. You do @UHN_Research @PMunkCardiacCtr @TBEP_UofT @trogersresearch @CIHR_IRSC proud!
Slava Epelman retweeted
Scientists @PMResearch_UHN led by @Schwartastic have developed CellNEST, a powerful AI tool that maps how cells talk to each other. By detecting complex signals between cells, it could lead to new ways to target tumours and stop disease progression. 🔗uhnresearch.ca/news/pinpointi…
Slava Epelman retweeted
Canada is stepping up in global #HealthInnovation. @UHN is launching the Canada Leads 100 Challenge - a bold initiative to recruit 100 top clinician-scientists from around the world. The goal? Transform Canada’s research economy.🔬
Slava Epelman retweeted
"Given the strength of the scientific evidence and the urgency of the public-health costs, we urge the scientific community and policy makers to recognize the addictive potential of ultra-processed food and its consequences." nature.com/articles/s4159…
Slava Epelman retweeted
Our Collaborative Centre for Clinical Research is leading the IA45 initiative with a goal that all clinical research studies can be activated in 45 days. Good for patients, good for research progress.
Our Collaborative Centre for Clinical Research is leading the IA45 initiative with a goal that all clinical research studies can be activated in 45 days. Good for patients, good for research progress.
Slava Epelman retweeted
Join us on Oct 2nd for our 10th Annual #HeartFailure Symposium! 🎉 💭 10-year retrospective & future insights 🎙️ Workshops, panels & social hour 🎟️ FREE for partner institutes (with a promo code) Register 👉 tedrogersresearch.ca/symposium/ #HFSymposium #HeartResearch #TRCHR
Slava Epelman retweeted
We can predict a person's risk of coronary artery disease better than ever before. Cover of new @NatureMedicine regarding our @ScrippsRTI @scrippsresearch recent paper @ATorkamani nature.com/articles/s4159…
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