everything we’ve been told about aging may be wrong scientists just discovered that the “biological clock” tracking your aging isn’t actually controlling it, it’s just reporting the damage. the real driver of aging are permanent dna mutations 1/

for years, researchers have treated epigenetic clocks (DNA methylation patterns that correlate with age) as a fundamental driver of aging itself. the assumption: reset the clock, reset aging. but what if the clock is just a byproduct of dna damage? 2/

researchers at UC san diego analyzed genome and methylation data from 9,300 people. what they found: somatic dna mutations (tiny, irreversible changes in your genome) map directly to methylation changes one mutation doesn’t just affect one site. it remodels entire dna regions 3/

@IterIntellectus That was actually one of the main arguments against the use off biological age clocks for a while. It's why doubt Bryan Johnson's routine is going to make him live (significantly) longer. He's faking the mileage of the car by spinning it back, but it's still the same car.

@IterIntellectus That was not the consensus among researchers of aging at all.

@IterIntellectus Who has seen it as a driver? Horvath has never said anything like that afaik.

@IterIntellectus It seems logical to be honest. Why would you assume that changing the clock winds back time? It was worth trying, but a long shot at best.