Valery Krizhanovsky @KrizhanovskyLab
Scientist at the Weizmann Institute. Senescence and Aging research weizmann.ac.il/mcb/valery/ Rehovot Joined September 2021-
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Valery Krizhanovsky retweeted
🎉Immune aging focus 🎉 @JuliaMMagdalena and @KrizhanovskyLab explore immune surveillance of senescent cells, including mechanisms of clearance, evasion and paracrine senescence, as well as therapeutic strategies nature.com/articles/s4358… rdcu.be/eARAC
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Thank you for featuring our review
Valery Krizhanovsky retweeted
How we’re rebuilding the Weizmann Institute — and our hopes for a better future nature.com/articles/d4158…
Valery Krizhanovsky retweeted
It took me more than 10 days before I could enter Ullman and climb to the burnt lab. Heartbreaking. Thankful to @WeizmannScience for helping us get up on our feet and look forward.
Nothing can break us!
Our new website is up and running!!! weizmann.ac.il/mcb/valery/
Very interesting study!
Very interesting study!
One very ineresting view on aging clocks and what they can or cannot tell us. 👇 nature.com/articles/s4159…
Valery Krizhanovsky retweeted
Save the date! @marc_dema announced that the next ICSA meeting will be held in Rome, marking the 10th anniversary of the ICSA meetings. Get ready for #ICSARome2025! 🇮🇹
Congrats Nurit. In this stidy we show that p21 might be master regulator of cellular microenvironment with a critical role in fibrosis. Thanks to all the coauthors.
Congrats Nurit. In this stidy we show that p21 might be master regulator of cellular microenvironment with a critical role in fibrosis. Thanks to all the coauthors.
Valery Krizhanovsky retweeted
Incredible program to apply to
Incredible program to apply to
Valery Krizhanovsky retweeted
Immunotherapy a key to fight aging? We break down our recent study in this animation! 🧪 Immune checkpoint anti-PD-L1 can enhance the immune system to remove senescent cells & ameliorate age-related phenotypes! nature.com/articles/s4155…… @JuliaMMagdalena @KrizhanovskyLab…
The business side of academic publishers... The question is what would be a better model?
The business side of academic publishers... The question is what would be a better model?
Valery Krizhanovsky retweeted
📑: @JuliaMMagdalena @amitmechaging et al fr/@KrizhanovskyLab show that p16-expressing senescent cells enhance the stability of the immune checkpoint PD-L1, by downregulating its proteasomal degradation to accumulate in ageing and chronic inflammation. nature.com/articles/s4155…
Valery Krizhanovsky retweeted
Happy to see our latest manuscript on the minimal set of markers to identify senescent cells in vivo out! Big effort with many excellent colleagues cell.com/cell/fulltext/… @Demarialab1 @UMCG_ERIBA @researchumcg
Valery Krizhanovsky retweeted
We show that p16 expressing #SenescentCells enhance PDL1 stability, by downregulating its ubiquitin-dependent proteasomal degradation to accumulate in #Aging and chronic inflammation. Anti-PDL1 activates an immune response to eliminate senescent cells and decrease inflammaging.
Valery Krizhanovsky retweeted
Immunotherapy as an anti-aging treatment? @KrizhanovskyLab we show that immune checkpoint anti-PD-L1 can enhance the immune system to remove senescent cells & ameliorate age-related phenotypes! @amitmechaging @UriAlonWeizmann @IdoAmitLab @WeizmannScience nature.com/articles/s4155…
Valery Krizhanovsky retweeted
Aging is a complex process, and one of its hallmarks is the accumulation of senescent cells. These cells, while once healthy, have become damaged and dysfunctional. But why do they stick around? 🤔 Our new research sheds light on this! #aging #senescentcells #aging…
Congrats @JuliaMMagdalena @amitmechaging . Thanks @UriAlonWeizmann for great collaboration.
Congrats @JuliaMMagdalena @amitmechaging . Thanks @UriAlonWeizmann for great collaboration.
Valery Krizhanovsky retweeted
In a new study published today in @NatureCellBio, researchers from Prof. @KrizhanovskyLab introduced the possibility of treating age-related diseases by immunotherapy – the same kind of therapy that is currently revolutionizing the treatment of cancer: harnessing the immune…
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