Monte Winslow's Lab @LabWinslow
Studying the Mechanisms of Cancer Progression and Metastasis. Account managed by lab members. Department of Genetics @StanfordMed @StanfordCancer med.stanford.edu/winslowlab.html Stanford, CA Joined March 2021-
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Monte Winslow's Lab retweeted
.@EmilyAshkin et al @LabWinslow underscore important roles of STAG2 in suppressing lung tumorigenesis & highlight a STAG2-PAXIP1/PAGR1 tumor-suppressive program that may transcend cancer type. hubs.la/Q02-Y7_D0 @HaiqingXu3 @kinglhung @HowardYChang @Jesse_R_Dixon @ZXuSalk
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Monte Winslow's Lab retweeted
Our latest preprint is online. Thanks to many in the lab for contributing to building these cell lines over the years including James’ and Alberto’s key contributions. biorxiv.org/content/10.110…
Monte Winslow's Lab retweeted
I'm thrilled to share our new study of the spatial evolution of Kras;p53-driven mouse lung adenocarcinoma! It's been fantastic leading this with @dianyang1117 & @sundakao, and enjoying a long-standing collaboration with @JswLab @YosefLab & @insitubiology. biorxiv.org/cgi/content/sh…
Monte Winslow's Lab retweeted
🚨🚨Now online @NatureCancer, my postdoc work in @SawyersLabMSKCC with @dana_peer 🚨🚨 we establish a powerful organoid transplantation model of prostate cancer neuroendocrine transformation. Open access for all! @HHMINEWS nature.com/articles/s4301… A 🧵... /1
Congratulations @dianyang1117 who did his PhD with @SageJulien and I some time ago… @stanfordcbio. Looking forward to some innovative things from him!
Congratulations @dianyang1117 who did his PhD with @SageJulien and I some time ago… @stanfordcbio. Looking forward to some innovative things from him!
Monte Winslow's Lab retweeted
So excited to welcome the new @stanfordcbio students in the annual labcoat ceremony!
Newest preprint from @EmilyAshkin in our lab! Critical roles of a STAG2 cohesin-PAXIP1/PAGR1 tumor-suppressive axis in lung cancer in vivo. Might transcend cancer type. Amazing collaboration with @ZXuSalk @Jesse_R_Dixon @HaiqingXu3@PetrovADmitri biorxiv.org/content/10.110…
Excited to be part of this study by @TonyBoutelle @AttardiLaura on the key effectors of p53 in cancer. We love quantifying gene effects in tumors in vivo. p53->Zmat3 is an important axis during lung tumor initiation @HaiqingXu3 @PetrovADmitri biorxiv.org/content/10.110…
Monte Winslow's Lab retweeted
Looking for help with grad school applications? Apply to the Stanford Cancer Biology PhD Preview Program for 1-1 mentoring and student-led workshops!!! More details at med.stanford.edu/cancerbiology/… Apply: bit.ly/CBioPreview
Amazing collaboration between @EmilyShuldiner and @Alberto_DiazJ using somatic genome editing to model 60 different genotypes of EML4-ALK lung cancer. Genetics say that Variant 1 and Variant 3 should be considered distinct oncogenes @SotilloLab biorxiv.org/content/10.110…
Epigenetic dysregulation is widespread in cancer. Using a new in vivo method, we generated a phenotypic roadmap of 250 epigenetic regulators in lung tumorigenesis in vivo. Most critical epigenetic tumor suppressors including one I hadn’t heard of before. biorxiv.org/content/10.110…
Monte Winslow's Lab retweeted
SCI member @LabWinslow explores key variables in designing assays for studying #metastasis, preclinical models, and potential anti-metastatic therapies. bit.ly/3K3EJ5y
Monte Winslow's Lab retweeted
NEW content online! Dissecting metastasis using preclinical models and methods dlvr.it/SnStjX
NEW review out today published with @SpringerNature in @NatureRevCancer by our very own Jess Hebert @AmericanCancer !! rdcu.be/dbfSR #Metastasis #MouseModels #Methods
It is always exciting to be reminded that people in lab are not only great scientists but also talented pumpkin carvers!
Monte Winslow's Lab retweeted
Had a fantastic time learning about ongoing research in #pancreaticcancer at the Pancreas Cancer Research Symposium at @Stanford. Was amazing to catch up with Sohinee from @MaraShermanLab and @hanson_kathrynj from the Attardi lab!!
Fantastic meeting at #cshlcancer22 ! Great to spend time with the very first Winslow lab grad student @drmcaswell and the most recent @EmilyAshkin ! Many generations of science!!
Oncogene-negative lung adenocarcinomas afflict as many patients as those driven by either oncogenic KRAS or EGFR. Our paper in @CR_AACR uncovers biochemical drivers and therapeutic liabilities of these cancers. Great collaboration with @PetrovADmitri lab! doi.org/10.1158/0008-5…
Congratulation to our amazing postdoc Rui Tang (@Ruitang16) for receiving an NCI K99/R00 grant to dissect the reciprocal interactions between cancer cells and endothelial cells during metastasis!
Monte Winslow's Lab retweeted
Excited to share the work from Noah “MC” Lee in the lab. Noah found a way to use Lenti-Cre and implement the Tuba-seq platform developed by @LabWinslow with the @PetrovADmitri lab in a mouse model of #SCLC, identifying TSC1 as a tumor suppressor in vivo biorxiv.org/content/10.110…
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