Bokai Zhu lab @LabZhu
The Zhu lab studies the moon/tide-related 12h ultradian clock; xbp1, proteostasis, epigenetic, metabolism, aging, stress response are the key words. @AgingPitt bzhulab.com Aging Institute, Divison of Endocrinology and Metabolism, Department of Medicine,Univeristy of Pittsburgh School of Medicine Joined June 2018-
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Bokai Zhu lab retweeted
#Postdoc opportunity at Columbia U. in New York! We are interested in candidates from biochemistry backgr. & excited about fractionation, purification and reconstitution to study autonomous clocks in the cell cycle, in colab. w/ @Aydinlab at NYU! hhmi.wd1.myworkdayjobs.com/External/job/C…
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GraphVelo allows for accurate inference of multimodal velocities and molecular mechanisms for single cells | Nature Communications nature.com/articles/s4146…
Bokai Zhu lab retweeted
LYVAC/PDZD8 is a lysosomal vacuolator | Science science.org/doi/10.1126/sc…
Bokai Zhu lab retweeted
Perhaps our boldest hypothesis… we propose a model for RNA Structural Memory propagation @NatureCellBio, where RNA conformation is reshaped by stress, locked by RBPs, copied prion-like in condensates & passed across generations—all without altering DNA.🧵 rdcu.be/eBwPJ
I completely agree.
Bokai Zhu lab retweeted
Academic scientists complain often about the hardship of their chosen career, but in reality research in academia is among the best jobs in the universe. I am at the end of my career, and here are my reasons why I would do it again any day:
Bokai Zhu lab retweeted
A multichaperone condensate enhances protein folding in the endoplasmic reticulum: nature.com/articles/s4155…
Bokai Zhu lab retweeted
Antiparasitic Drug Shows Power Against Alzheimer’s and Dementia today.ucsd.edu/story/antipara…
Bokai Zhu lab retweeted
Excited to see the work by @Yale_INP students Suzhou Yang @Denethi_W w/ collabs @YaleNeuro iPSC core @jdpereira @ArabTanina and @MayoClinicNeuro @gendron_tania @NeuroUdit on #C9orf72 #ALS & #FTD finally out in @NatureNeuro! @WuTsaiYale @KavliAtYale nature.com/articles/s4159…
Nuclear speckle rejuvenation “next frontier” for treating neurodegeneration, via @EurekAlert! eurekalert.org/news-releases/…
A news article on our work. Nuclear Speckle Rejuvenation “Next Frontier” for Treating Neurodegeneration - UPMC & Pitt Health Sciences News Blog inside.upmc.com/nuclear-speckl…
Left by the tides | Pitt Med Magazine | University of Pittsburgh. A nice piece on our earlier work on identifying 12h rhythms in ‘free-living” humans. pittmed.pitt.edu/news/12-hour-b…
This is a very good review on ~12h biological rhythms. Biological rhythms: Living your life, one half-day at a time | npj Biological Timing and Sleep nature.com/articles/s4432…
Interesting work. 12h rhythms of lipid metabolism in the Drosophila fat body, independent of the circadian clock. Circadian clock-independent ultradian rhythms in lipid metabolism in the Drosophila fat body - Journal of Biological Chemistry jbc.org/article/S0021-…
Bokai Zhu lab retweeted
This is like AlphaFold, but for protein localisation rather than folding It's a deep learning model that predicts a protein's subcellular compartment based on its amino acid sequence alone:
Bokai Zhu lab retweeted
The Aging Institute is pleased to share the most recent edition of our newsletter, The Chronos Chronicle, Winter 2025. Read more about the exciting research happening at the Aging Institute here: aging.pitt.edu/newsletter-win…
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