Rapamycin News @RapaNews
Rapamycin (and other longevity drugs) user group, news & discussion forum. New research, clinical science, and user's results. Partnering with geroscientists. rapamycin.news San Francisco, CA Joined November 2019-
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The use case for the use of rapamycin for the preservation of ovarian health is one that we've been watching. This comports with some of the results our patients are having. Thank you @RapaNews for sharing. x.com/RapaNews/statu…
The use case for the use of rapamycin for the preservation of ovarian health is one that we've been watching. This comports with some of the results our patients are having. Thank you @RapaNews for sharing. x.com/RapaNews/statu…
"Why haven't we brought in the backhoes? Why haven't we industrialized this and sifted through the space?" @mitchellblee33 and @mkaeberlein discuss the state of drug discovery in the longevity field and how they're working to improve it. youtu.be/Lon8J-GMw48
We are getting more and more positive results of rapamycin reversing ovarian aging / menopause: rapamycin.news/t/rapamycin-to…
Could a rare mutation that causes dwarfism also slow ageing? nature.com/articles/d4158…
Here are some poll results from the Buck Institute’s Student Aging Symposium! Exciting to see how many of the top aging scientists think about the field and the future of longevity
"Rapamycin increases mitochondrial efficiency by mtDNA-dependent reprogramming of mitochondrial metabolism in Drosophila" 👇 ncbi.nlm.nih.gov/pmc/articles/P… #rapamycin @rapa #mitochondria
The interventions that the ITP accepts range from boring FDA approved to way out there. I wish they would just publish a brief abstract for each explaining the decision. Come on, it is only 10 minutes of work.
A Peek Inside the Brains of ‘Super-Agers’ "New research explores why some octogenarians have exceptional memories..." nytimes.com/2024/04/29/wel… | @nytimes
@mkaeberlein On this page I have gathered a list of all the great Rapamycin episodes Matt has done on the Optispan podcast. rapamycin.news/t/questions-to…
WORLD SUPERCENTENARIAN RANKINGS LIST grg-supercentenarians.org/world-supercen…
Rapamycin improves the survival of epilepsy model cells by blocking phosphorylation of mTOR base on computer simulations and cellular experiments. sciencedirect.com/science/articl…
People with Laron syndrome have a low risk of heart disease and a number of other age-related disorders, hinting at strategies for new treatments go.nature.com/49Qc9yl
The Dog Aging Institute is dedicated to enriching the lives and welfare of companion dogs through funding innovative research and programs.Together, let's make a real difference in the lives of our beloved canine friends. Please donate today at dogaginginstitute.org/donate.
Dorothy Hoffner gained international adoration for becoming the oldest person to eve skydive at age 104 at the end of 2023. Sadly she died in her sleep few days later at her home in Chicago.
The same mutation that causes short stature in Laron syndrome may also help people live longer by protecting them from heart disease. newscientist.com/article/242863…
1/ Announcing COHORT 4 of the Longevity Biotech Fellowship! Aging can be defeated. We're building a plan. We need humanity's top talent to join the revolution against aging! Apply now: longbiofellowship.org/apply ⏳ LBF4 Deadline April 30 🇪🇸 Kickoff May 15-19 Valencia Spain
Live-stream interview with @mkaeberlein taking place at 18:00 CET today. Signup here: 🔗forms.gle/ywzzXUdYL1sdvT… Hosted by @LinusPeters
Rubedo Life Sciences, backed by the @vita_dao community, lands $40M in Series A funding to advance senescence-targeting therapeutics into clinical trials Round led by @khoslaventures & Ahren Innovation Capital. Congrats to @MarcoQuarta12 and the team! 💛 businesswire.com/news/home/2024…
@NerdSharo @DrGrahamLJ @danaparish @DogAgingProject @BayAreaLyme @PutrinoLab @microbeminded2 @loscharlos @TRyanGregory @VirusesImmunity @ImmunoFever @polybioRF @ChrisCuomo @TheDailyShow Jon An at the University of Washington is currently enrolling for a clinical trial to find out: rapamycintrial.com
Our Rapamycin Trial has surpassed 70 enrollees! We are well on our way to our goal of 100 participants. #ME patients need treatments, & Simmaron foundation is doing that work. Learn more about our trial here. #MECFS #POTS #LongCovid simmaronresearch.com/rapamycin-trial
Matt Kaeberlein @mkaeberlein
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1K Followers 100 Following Biology of homeostasis & tech dev. Incoming asst prof @StanfordDevBio. @Harvard Junior Fellow, neuro Ph.D. @Stanford, MPhil @MRC_LMBThe use case for the use of rapamycin for the preservation of ovarian health is one that we've been watching. This comports with some of the results our patients are having. Thank you @RapaNews for sharing. x.com/RapaNews/statu…
We are getting more and more positive results of rapamycin reversing ovarian aging / menopause: rapamycin.news/t/rapamycin-to…
Instead of a large animal (mice🐀), we decided to investigate the effects of in vivo reprogramming in a smaller one (worms🪱). Happy with the results and excited about the new experiments that we are currently performing, which would take years in mice. The best is yet to come!
New Preprint Alert! Induction of in vivo reprogramming in C. elegans has negative effects during development and is highly toxic. Congratulations to @haque_nibrasul members of @OcampoLab and collaborators! The best is yet to come! 🪱 biorxiv.org/content/10.110…
New Preprint Alert! Induction of in vivo reprogramming in C. elegans has negative effects during development and is highly toxic. Congratulations to @haque_nibrasul members of @OcampoLab and collaborators! The best is yet to come! 🪱 biorxiv.org/content/10.110…
Looking forward to the debate between @fedichev and @aubreydegrey at @foresightinst. Add it to your calendars and enable the broadcast reminder on YouTube: youtube.com/watch?v=g7Uwkf…
You might have noticed that I often ask for likes and reposts on my tweets, referring to the struggle between kind and wicked memes in our longevity community. In the field of anti-aging medicine, there are at least three particularly detrimental narratives: * Aging is solved:…
All previous episodes of the Optispan Podcast with @mkaeberlein are here, along with some pretty cool resources: optispan.life/podcast
I highly urge you to check out Bottle of Lies: The Inside Story of the Generic Drug Boom, written by award-winning journalist @KatherineEban. It features my personal story and work that I do to protect our drug supply: harpercollins.com/9780062338785/…. #BottleOfLies #PublicHealth #Health
"Why haven't we brought in the backhoes? Why haven't we industrialized this and sifted through the space?" @mitchellblee33 and @mkaeberlein discuss the state of drug discovery in the longevity field and how they're working to improve it. youtu.be/Lon8J-GMw48
This has to be one of the dumest things someone posted on Twitter today. This bioreactor somehow makes lab meat bad?
Amino acid restriction, aging, and longevity: an update 🔘"It is time to determine in human studies whether these low these amino acid restricting diets unlike chronic DR, are sustainable over the long-term and what the long-term health consequences might be..." 🔘"We have…
Excited to see the first 5 papers published from our MoTrPAC Study Group. Paper #1 in Nature: nature.com/articles/s4158… Editorial: nature.com/articles/d4158…
A small-molecule inhibitor that counteracts epigenetic silencing to enhance myelin production and re-myelination in mice & organoids to reverse age-related cognitive decline @cellcell #LuLab @CincyChildrens @ChildrensCBDI cell.com/cell/fulltext/… scienceblog.cincinnatichildrens.org/small-molecule…
Could a rare mutation that causes dwarfism also slow ageing? nature.com/articles/d4158…
@longevion Which "biohacks" move the needle? If there are ones, I'd be interested, but there's a chronic lack of evidence. Perhaps if the biohacker community could run actual efficacy trials? If we had validated biomarkers for aging? I'd like to see these things happen.
@GordianBio launched with $60 million in venture capital and a groundbreaking platform aimed at revolutionizing the discovery of gene therapies for age-related diseases. 👍👍👍 longevity.technology/news/gordian-l…
pretty interesting how at fairly traditionalist longevity research institutions there's a strong emotional reaction against living-forever rhetoric despite an actual high desire to live forever. ultimately debate comes down to optimism/hype and worries of public reaction to it
Here are some poll results from the Buck Institute’s Student Aging Symposium! Exciting to see how many of the top aging scientists think about the field and the future of longevity
Here are some poll results from the Buck Institute’s Student Aging Symposium! Exciting to see how many of the top aging scientists think about the field and the future of longevity
📢 #CallForPapers The Call - “Enhancing #healthspan through #antiaging dietary interventions" - is focusing on the impact of diverse #dietaryinterventions and eating patterns on age-related physiological decline in various organ systems, as well as their role in preventing and…
This post was instigated by recent examples I personally witnessed of people citing do-no-harm in discussions even within the context of "longevity medicine". Frustrating. Anyone 60+ w/ no med treatment for 10+yrs still suffers significant harm inc. raised mortality & morbidity.
@KristerKauppi In a recent Optispan podcast, @mkaeberlein also pointed out that the half life of rapamycin may be a lot shorter than we all assumed: 24 hours or even less, rather than 60+ as in the kidney transplants. I take rapa on my rest day and exercise like a lunatic the other six.