LCAP (Long Covid Action Project) @LongCovidAP
LCAP is a united, diverse force of non-partisan individuals taking action to end the Long Covid crisis through awareness & government accountability. linktr.ee/longcovidactio… Washington, D.C. Joined January 2023-
Tweets2K
-
Followers3K
-
Following135
-
Likes3K
@2022onward @HELPCmteDems @GOPHELP Moonshot does too little, too slowly. I need antivirals now, not in 10 years or more. I helped write @LongCovidAP's legislation, based on what has successfully been implemented to research and care for people with HIV. x.com/amymitchellart…
@2022onward @HELPCmteDems @GOPHELP Moonshot does too little, too slowly. I need antivirals now, not in 10 years or more. I helped write @LongCovidAP's legislation, based on what has successfully been implemented to research and care for people with HIV. x.com/amymitchellart…
NEW: Sen. Bernie Sanders’ $10 billion long COVID research proposal received mixed reviews from patient-advocacy groups ahead of his April 23 comment deadline. But these recommendations could influence what Sanders includes in the final bill. My latest: dlvr.it/T5ywRm
4. Yes we can! Viral antisense RNA is a "decent" diagnostic biomarker for #LongCovid but together with immune marker FYN it's even better: 4.1. multivariate logistic regression (corrected for age and sex, table below) 4.2. identify Long COVID with >90% sensitivity and specificity
So now some statistics to answer the following: 4. can we use persistent RNA in blood (+/- 2 years after acute COVID in this cohort) as a diagnostic biomarker for #LongCovid? 5. what predicts high vs. low blood viral load in #LongCovid?
It's a short paper so details are in the Appendix 🤓 Look below at the very homogeneous controls (green) and the wild variation among #LongCovid patients: some are similar to controls but half are "deficient" in lymphocyte activation and immunometabolism -> higher viral load!
@JoshuaPribanic Antisense RNA is only found inside a cell with replicating virus, so yes
@johanvawe Thank you. @zeynep please see this answer & use studies at longcovidfacts.com to correct @NIHDirector about existence of SARS2 live virus detected via viral load tests, of which those w/in NIH confirmed to LCAP they have been using w/out data shown to public
@JoshuaPribanic @Julia_Daye @itsJalenB @corbett_jessica @jacksontom @microbeminded2 @LastBornPodcast @NIHDirector @NIH @NIHceal @HHSGov Excellent thread describing more details and the significance of this work from one of the authors of the study:
@JoshuaPribanic @Julia_Daye @itsJalenB @corbett_jessica @jacksontom @microbeminded2 @LastBornPodcast @NIHDirector @NIH @NIHceal @HHSGov Excellent thread describing more details and the significance of this work from one of the authors of the study:
📣 Speaker announcement 📣 A warm welcome for our next speaker! Johan Van Weyenbergh (@johanvawe ) joins #UniteToFight2024 ! We are very happy to have you with us on this journey! 🙏 #longcovid #mecfs
If you have time to read only one thread by a Long Covid researcher today, make this be the one!
If you have time to read only one thread by a Long Covid researcher today, make this be the one!
#LongCovid is complex to diagnose and treat, so we need #biomarkers! 1. to confirm viral persistence, and 2. to map the failing/overactive immune response. So we tried to hit two birds with one stone using digital transcriptomics 👇👇 (1/n) thelancet.com/journals/lanmi…
We believe clinically useful #biomarkers should be non-invasive: while it is interesting to know what happens with #SARSCoV2 in muscle or colon/gut, these biopsies are too painful and laborious to integrate in daily care for #LongCOVID patients. Hence a blood test!
Looking at viral RNAs above cutoff (red line below) comparing patients and controls: antisense (65% vs 25%), ORF7a (60% vs 25%), Nucleocapsid (50% vs 8%), total blood viral load (60% vs 8%). Remarkably, Spike RNA was low in all cases =infection not vaccine-derived
What did we find? 1. viral RNAs were higher in #LongCovid: Nucleocapsid, ORF7a, ORF3a, Mpro (=Paxlovid target), and antisense ORF1ab RNA. Of note, presence of antisense RNA suggests ongoing viral replication 2. #SARSCoV2-related host RNAs ACE2/TMPRSS2, DPP4/FURIN also higher!
This THE 🩸 transcriptomic viral load test we’ve been highlighting at LCAP & to the press since it came out - shouting for NIH to open access to its SARS2 transcriptomic viral load tests to people w/ Long Covid that’s in use behind closed doors #AntiviralsNow #ViralLoadTestsNow
This THE 🩸 transcriptomic viral load test we’ve been highlighting at LCAP & to the press since it came out - shouting for NIH to open access to its SARS2 transcriptomic viral load tests to people w/ Long Covid that’s in use behind closed doors #AntiviralsNow #ViralLoadTestsNow https://t.co/qgtsP1JNPU
I could use your help reaching my fundraising goal. Every single share and donation makes a difference. gofund.me/68d7140c
I just wrote @LongCovidAP's "Tell @SenSanders to Enact the HEAL Legislation Proposal for Long Covid" Get Loud! We need Long Covid legislation that creates: Viral Load Tests Now! #AntiviralsNow! $28B+ Now! Sign the letter! actionnetwork.org/letters/tell-b… #HELPHEALUS #SARS2
@Partikel007 @bfrde @InspekteurSan @BVerfG 🎬 Anbetracht der vielen offenen Fragen zur intrinsischen Virulenz und zukünftigen Langzeitfolgen durch wiederholte Exposition zu #SARSCoV2 und deren Persistence sollten Kindern, Vulnerablen, Patienten besonderer Infektionsschutz angedeiht werden 📽 x.com/joshuapribanic…
@Partikel007 @bfrde @InspekteurSan @BVerfG 🎬 Anbetracht der vielen offenen Fragen zur intrinsischen Virulenz und zukünftigen Langzeitfolgen durch wiederholte Exposition zu #SARSCoV2 und deren Persistence sollten Kindern, Vulnerablen, Patienten besonderer Infektionsschutz angedeiht werden 📽 x.com/joshuapribanic…
I just wrote @LongCovidAP's "Tell @SenSanders to Enact the HEAL Legislation Proposal for Long Covid" Get Loud! We need Long Covid legislation that creates: Viral Load Tests Now! #AntiviralsNow! $28B+ Now! Sign the letter! actionnetwork.org/letters/tell-b… #HELPHEALUS #SARS2
I just wrote @LongCovidAP's "Tell @SenSanders to Enact the HEAL Legislation Proposal for Long Covid" Get Loud! We need Long Covid legislation that creates: Viral Load Tests Now! #AntiviralsNow! $28B+ Now! Sign the letter! actionnetwork.org/letters/tell-b… #HELPHEALUS #SARS2
Slurethoughs @slurethoug7146
0 Followers 199 FollowingClean Air Boorloo @cleanairboorloo
0 Followers 30 FollowingLong Covid Belgium @TooLongCovidBe
157 Followers 49 Following Compte de l'association belge francophone Long CovidGaye @Eliza345192
21 Followers 1K Following I am a lively and cheerful girl who would like to meet a good friend.Happy Elshohdi @Happy_elshohdi
190 Followers 478 FollowingJohan Van Weyenbergh @johanvawe
4K Followers 4K Following Researcher in #HTLV #HIV #NTDs respiratory viruses and vaccine response. 'Nothing in #human #immunology makes sense outside the light of #clinical #evolution'Albertan8181 @albertan8181
105 Followers 1K Following Alberta human. #Volunteer #Community #Inclusion #Adventure #Wellness #Nature #YEG #YYCLongCovid Stories @LonghaulStories
51 Followers 24 Following☄PARTIKEL 🩻 prev.. @Partikel007
247 Followers 3K Following humanist ✨️ until we arent dead we are alive🌅 be proactive a gamechanger🔥 🔎 since:2021-10-01 until:2023-06-26 kaddand67376085 https://t.co/oHoUri2gaWIna • me/cfs @tink_ina
823 Followers 288 Following #mecfs 12 years, severe. bedbound w near fatal spine injury causing a yet to be diagnosed neuromuscular condition. 🇸🇪Robert DeRosa @Rob_DeRosa
346 Followers 836 Following 🇨🇦 🇺🇸 CAN/AM. Previous res of Japan & Singapore. Former teacher. Master in Public Policy. Disabled by #LongCOVID #MECFS since February 2020.🌺 Allison Shapiro .. @ARShapiro68
980 Followers 560 Following Special educator disguised as a first grade teacher; closet techie; wino & foodie.#FreeAssange @fascismcantwin
266 Followers 1K Following My body is materially disabled. MECFS, EDS, & more.:) @user37252919
13 Followers 607 FollowingMrsM🦖💚🤍💜 @MrsM45184173
902 Followers 5K Following I sincerely hope that my disquieting predictions are comprehensively invalidated! #pwME/CFS/FM, #WomenWontWeesht, #1dayatatime 🫖☕️UnhappySisyphus @NikeyNiki47281
74 Followers 477 FollowingCheryl @Cdnn58
5 Followers 162 FollowingDave Satterlee @dsatt5
64 Followers 275 Followingmack_longcovid @mack_Kartikeya
109 Followers 618 Following (Rajasthan, IND) 🏳️🌈 Long Covid-19 - Looking for advice, research,trials & treatments. Here to share success stories / wins / learnings. Om ShantiLiz Bruce @mannatechbiz
128 Followers 363 Following love life! Social networker, expert on health, nutrition. fat loss. Free to travel the world, join me! Transform your Life!!Peter Herring @Phermes54
2K Followers 5K Following To change something, build a new model that makes the existing model obsolete -B. Fuller. Long covider, zen buddhist, socialist, poet/writer, BLM, antifa...Caitlin Nichols, PhD @caitlinanichols
790 Followers 1K Following @Harvard Biomedical Sciences PhD | Writer, editor, speech geek, tap dancer | #cancergenomics #scicomm #raredisease | Views my ownMo’s Mom @jerseygirlinatx
1K Followers 3K Following Retired, traveler, cook, photographer, gardener. Mother 2 Frida Katlo, Stella Luna (tic) and Mo the Big Maine Coon (RIP) #Betocrat #ForeverBeto #BidenHarris2024GrahamH @hazlegs
9 Followers 419 FollowingHenning @HopeHenning
256 Followers 4K FollowingJ Peace 3 @JPeaceJPeace
31 Followers 90 FollowingGail Rule-Hoffman @grulehoffman
15 Followers 80 FollowingAlan S @AlanS71420449
158 Followers 112 Followingten raccoons @SaysEwe
203 Followers 2K Following looking for something | born screaming | fella #RussiaIsATerroristStateArialla MacAllister �.. @AriallaFio
357 Followers 4K Following A random GenX nerd. I like dance, history, art, fabric, books, & games. She/Her. Love is a verb. Life is amazing. You matter. Banner art by @FalSkyWolfMorgan Corrington @MCorringto70434
9 Followers 61 Following Former NP in Wyoming. Now visually impaired due to Covid-19. I’m here to listen to spaces and not read the timeline so please don’t follow.Diana Divecha @DianaDivecha
802 Followers 530 Following Developmental psychologist, Asst Clinical Prof Yale Child Study Ctr. I write about research on children.Timika @nalanea
222 Followers 998 Followingjezzie0987 @jezzie0987
78 Followers 361 FollowingElizabeth Vega @elivegatss
3K Followers 5K Following Trabajadora Social Sanitaria. Formadora Impacto Social #LongCovid. Investigadora @LabTraslacional. #CovidIsAirborne #MareaRosa @covid_madrid #LongCovidKids 🙌Crystal 💙💛 @Crystals_smile
548 Followers 3K Following Mental health nurse. Empowering others and instilling hope is an honor. There is always light somewhere. I love wellness, music and the arts.Four-Penny Fox @FoxfireOnline
24 Followers 172 Following I'm a sarcastic Southern Sagittarius DbD streamer with a family and a day job. She/HerLindsey Pederson @PedersonLindsey
291 Followers 712 Following Small town girl living in a city; trying to figure out how to raise a toddler; prolific retweeter; healthcare worker; #N95, #Covidisairborne, #POTS(ON HIATUS) @jonah_mcgarva
2K Followers 3K Following Always seen; Never heard. co-founder of @LongCovidCanada Kānaka Maoli #ActuallyAutistic #LongCovidezRks @ez_rks
110 Followers 519 FollowingRenate-new account�.. @Renate834601
83 Followers 423 Following Myalgic Encephalomyelitis since -87,severeME,Bedbound, diagnosecriteria /name matters!separate ME from ME/cfs; use ICC -G93.3 for ME❤️#EnterovirusIssa @capy_sommelier
34 Followers 298 FollowingCamila @camilashaw5149
0 Followers 7 FollowingLong Covid Belgium @TooLongCovidBe
157 Followers 49 Following Compte de l'association belge francophone Long CovidJohan Van Weyenbergh @johanvawe
4K Followers 4K Following Researcher in #HTLV #HIV #NTDs respiratory viruses and vaccine response. 'Nothing in #human #immunology makes sense outside the light of #clinical #evolution'jellyrollblues #Covid.. @jlerollblues
6K Followers 6K Following father, retired scientist PhD, Covid modeler , liberal, artist, history buff, deadhead #NoRA #union #IChooseScience https://t.co/M6oCUBv5MIEileen 🔊 @TurnItUp4ME
2K Followers 933 Following Advocate; Former Federal Committee Advisor, Department of Health and Human Services, Washington, DCth_Redd @robynasaldino
2K Followers 1K Following She/Her, Sober, #LongCovid, AuDHD, CPTSD, effective resource-sharing. We are all we have. #CovidIsNotOver https://t.co/PMQTVySGyvJalen Brown @itsJalenB
6K Followers 5K Following Congressional Health Care Reporter @InHealthPolicy | Past: @BGOV, @CNN, @Forbes | @NABJ | ❝The people must know before they can act...❞ — Ida B. WellsAmy Mitchell @amymitchellart
3K Followers 2K Following Artist & Pet Sitter 🐈 Lyme, MCAS, CVID, APS1, POTS, gluten ataxia, #longcovid https://t.co/iKR4aqhKtWTom Jackson @jacksontom
1K Followers 923 Following Sandusky Register scribe. Like: science fiction, Asian food, Robert Anton Wilson, civil liberties, 20th century Russian composers.Opinions mine, not Register's.Long Covid Institute @LCInstitute
10 Followers 8 Following Long Covid International Relations Think Tank (coming soon)Marco Wetzel (is figh.. @Gmwetz
2K Followers 836 Following Founder of @U2Fight_world // #UniteToFight2024 // #LongCovid and #MECFS advocate // #longcovid patientRenee. Long Cvid 💀.. @LCaddams
117 Followers 168 Following 1st wave Long Covid sufferer. I also like dinosaurs.MaskTogetherAmerica @TogetherWeMask
5K Followers 2K Following We advocate for people threatened by COVID-19 by promoting the multi-layered approach in mitigation measures. Let’s stay COVID-SMART.Julie O'Connor @julieoconnorNJ
788 Followers 970 Following Editorial board member at The Star-Ledger. Parallel parking ace. Board opinions aren't always my own; sometimes they are the product of a debate that I lost.Ian @idsimon
162 Followers 218 FollowingIrene Wright @IreneEWright
118 Followers 177 Following McClatchy National Real Time Reporter, ATL @mcclatchy national and international health and discovery || UGA grad x2 || words @dallasnews @universityofgaSARS-CoV-2 Action Can.. @SARS2ActionCAN
65 Followers 1 Following An independent, non-partisan group of Canadians demanding action from all levels of government to urgently address the SARS-CoV-2 crisis in Canada.M. C. Benner Dixon @mchristinebd
586 Followers 771 Following Author, educator, aspiring photosynthesizer. She/her. Interim ED @WritePittsburgh | MILLIONS OF SUNS @UofMPress | THE HEIGHT OF LAND @OrisonBooks forthcomingOptOut News @optoutnews
7K Followers 323 Following A nonprofit charity with a mission to elevate trustworthy, independent media. Free curated news app out for iOS and Android.Roey Hadar @roeyhadar
2K Followers 6K Following Producer for "Scripps News Tonight" @ScrippsNews. @Jeopardy Champion. Jersey Shore is home. He/Him/His If DMs don't work then email me✉️: [email protected]Julia Daye @Julia_Daye
253 Followers 443 Following National Reporter @mcclatchy. Words @miamiherald @sacbee_news @theobserver @huffpost @phillyinquirer @taosnews. Past: @TrueTaosRadioThe Intercept @theintercept
874K Followers 335 Following Fearless, adversarial journalism. Join our newsletter to get our best investigative reporting delivered to you: https://t.co/eYtvizHD22Appalachians Against .. @stopthemvp
8K Followers 276 Following Defending Appalachia from the Mountain Valley Pipeline, Atlantic Coast Pipeline, and more. No new pipelines in Appalachia!Climate Defiance @ClimateDefiance
39K Followers 1K Following Brand-new, youth-led group using direct action to resist fossil fuels.RisingTideAustralia @RisingTideAus
3K Followers 2K Following Grassroots #climate activism in the world's biggest #coal port. #climateemergencyRising Tide Seattle @RisingTideSEA
2K Followers 2K Following #Grassroots, all-volunteer #collective taking #DirectAction to confront the root causes of #ClimateChange.Rising Tide North Ame.. @RisingTideNA
14K Followers 5K Following Confronting the Root Causes of Climate ChangeTaylorLorenz.Substack.. @TaylorLorenz
342K Followers 10K Following Tech reporter, host of Power User podcast on Vox Media. Buy my book EXTREMELY ONLINE (out now!) Subscribe to my YouTube 👇🏻👇🏻👇🏻Winnie 🇨🇦 🦘�.. @CockapooWinnie
282 Followers 734 Following Proud mom of 2 amazing kids, wife and engineer! Lover of ⛷️🥾 🌳 🌸 📚 🎶 🌊 🧳 👯♂️ On a mission to spread kindness to everyone everyday! Long COVID ❤️ ✌️CalBear @cal_bear_girl
515 Followers 242 FollowingYes, Vasser is my fir.. @Vasserbee
972 Followers 1K Following [email protected] Will volunteer for #LongCOVID trials. #HELPHEALUSDr. Sean Mullen @drseanmullen
23K Followers 6K Following Research Director @EtcLab studying #Exercise #Technology #Cognition #Neuroscience | Husband | Dad | #MartialArtist | #PTRTennisProTLC NOW Treat Long CO.. @TLCNOWaction
33 Followers 24 Following Group advocating for treatment of long COVID #treatlongCOVID #longCOVIDPyke @Pyke_Wielder
752 Followers 882 Following Biologist & non-consenting subject in a global open-air GOF research project, debilitated by SARS2 & watching the world burn. Prior account⚰️. X free speech=liesillypaulie @we_are_ssd
2K Followers 2K Following #DavosSafe Prometheus stole fire from the gods and gave it to man. For this, he was chained to a rock and tortured for eternity.Deborah Holloway 😷.. @DebHolloway
6K Followers 4K Following Former Prof. Communicator. Infected Mar 13/2020. 1st Wavers identified & named OUR disease. It is LONG COVID. Switch flipped: from victim to WARRIOR. #LongCovidTara Cobham @taracobham
1K Followers 2K Following general reporter @Independent | prev @bbcsoutheast | [email protected] | she/herLC/DC (Awareness Day .. @LCDCmarch15
2K Followers 208 Following https://t.co/McGz8ndGEH We're going to DC for LC 3/15/25 Long Covid Awareness Day Demand action for Long Covid and Covid prevention!Long COVID Foundation @LongCFoundation
801 Followers 85 Following USA based 501(c)(3) non-profit focused on supporting those with Long COVID & others affected by the COVID Pandemic.PolyBio @polybioRF
10K Followers 2K Following 501(c)3 transforming how #LongCovid, #ME/CFS & LongLyme are studied, diagnosed, and treated. Leading the #LongCovid Research Consortium.Amy Proal, PhD @microbeminded2
29K Followers 5K Following Microbiologist at PolyBio Research Foundation: helping research teams collaborate on infection-associated chronic disease #me #longcovid #lyme #eds @polybioRFDanilo.Buonsenso_Surf.. @surf4children
3K Followers 661 Following Pediatrician/pedsID working on #longcovidkids, #TB, #congenitalinfections☀️funder of surf4children no profitMichael VanElzakker @MBVanElzakker
10K Followers 290 Following Neuroscience researcher @MGHMartinos / @HarvardMed and @PolyBioRF, researching #MEcfs, #LongCOVID, & #PTSD. (all opinions are my own)Michael Peluso, MD @MichaelPelusoMD
4K Followers 80 Following Infectious disease doctor @UCSF. #LongCOVID researcher. #HIV clinician and #HIVcure researcher.Emma 🌲 @peaksandwaves00
702 Followers 343 Following • Life in the countryside 🌲 • Hiking peaks, riding waves, exploring caves✌🏽 • Trying to survive LongCovid and Dysautonomia July 2022 #TreatlongcovidAssociation Winslow S.. @winslow_la
2K Followers 2K Following Citoyens, malades, CovidConcerné-es, médecins, humanistes vs le populisme sanitaire -winslowsp sur bsky - ➡️ Réhabiliter la santé publique https://t.co/qTk6KgyMEPSolenn TANGO @Eerrnn
2K Followers 3K Following Militante Santé Publique @solenntango.bsky.social Asso @winslow_la 🐘 338ppm Prof éthique, justice sociale, inegalités... LC / EP illness "in ffp2 we trust"@2022onward @HELPCmteDems @GOPHELP Moonshot does too little, too slowly. I need antivirals now, not in 10 years or more. I helped write @LongCovidAP's legislation, based on what has successfully been implemented to research and care for people with HIV. x.com/amymitchellart…
The comment period for @SenSanders #LongCOVID legislation ends sometime tomorrow April 23. Don't forget to personalize and send your @LongCovidAP letter. 🏥👩⚕️🧪 #healus #helphealus actionnetwork.org/letters/tell-b…
@The_BMC @RepPressley @HHSGov How much discussion was focused on SARS2 viral persistence, transcriptomic #ViralLoadTestsNow & #AntivirlalsNow? What was the discussion focussed on regarding #LongCovid?
@CockapooWinnie Shouldn’t someone have to give a reason at some point for this? It’s not like impulsively buying skittles at 7-11 and not explaining. This is serious stuff. I agree we definitely need more. The math doesn’t add up.
NEW: Sen. Bernie Sanders’ $10 billion long COVID research proposal received mixed reviews from patient-advocacy groups ahead of his April 23 comment deadline. But these recommendations could influence what Sanders includes in the final bill. My latest: dlvr.it/T5ywRm
Research Moving toward viral load test for #longcovid 👇#covid #bloid #fatigue #cough #depression #anxiety #copd #asthma
The #SARSCoV2 viral RNA signature in people with #LongCovid markedly differs vs controls thelancet.com/journals/lanmi… @LancetMicrobe Also linked to symptoms. Not only indicative of persistence, but also potential as a biomarker @johanvawe @jamoulle @KU_Leuven
4. Yes we can! Viral antisense RNA is a "decent" diagnostic biomarker for #LongCovid but together with immune marker FYN it's even better: 4.1. multivariate logistic regression (corrected for age and sex, table below) 4.2. identify Long COVID with >90% sensitivity and specificity
So now some statistics to answer the following: 4. can we use persistent RNA in blood (+/- 2 years after acute COVID in this cohort) as a diagnostic biomarker for #LongCovid? 5. what predicts high vs. low blood viral load in #LongCovid?
It's a short paper so details are in the Appendix 🤓 Look below at the very homogeneous controls (green) and the wild variation among #LongCovid patients: some are similar to controls but half are "deficient" in lymphocyte activation and immunometabolism -> higher viral load!
@JoshuaPribanic Antisense RNA is only found inside a cell with replicating virus, so yes
@johanvawe Thank you. @zeynep please see this answer & use studies at longcovidfacts.com to correct @NIHDirector about existence of SARS2 live virus detected via viral load tests, of which those w/in NIH confirmed to LCAP they have been using w/out data shown to public
@KevCTNC @Julia_Daye @itsJalenB @corbett_jessica @jacksontom @microbeminded2 @LastBornPodcast @NIHDirector @NIH @NIHceal @HHSGov It’s live SARS2 in 92% of those tested w/ Long Covid in the transcriptomic viral load study - see thread & researchers answer. Folks have been using word games to dodge this for over a year - we need #ViralLoadTestsNow #AntiviralsNow @SenSanders @NIHDirector @NIHDirector
@johanvawe Thank you. @zeynep please see this answer & use studies at longcovidfacts.com to correct @NIHDirector about existence of SARS2 live virus detected via viral load tests, of which those w/in NIH confirmed to LCAP they have been using w/out data shown to public
@JoshuaPribanic @Julia_Daye @itsJalenB @corbett_jessica @jacksontom @microbeminded2 @LastBornPodcast @NIHDirector @NIH @NIHceal @HHSGov Excellent thread describing more details and the significance of this work from one of the authors of the study:
#LongCovid is complex to diagnose and treat, so we need #biomarkers! 1. to confirm viral persistence, and 2. to map the failing/overactive immune response. So we tried to hit two birds with one stone using digital transcriptomics 👇👇 (1/n) thelancet.com/journals/lanmi…
Great Work!! Thank you! Viral Persistence!! We need Biomarkers!
#LongCovid is complex to diagnose and treat, so we need #biomarkers! 1. to confirm viral persistence, and 2. to map the failing/overactive immune response. So we tried to hit two birds with one stone using digital transcriptomics 👇👇 (1/n) thelancet.com/journals/lanmi…
📣 Speaker announcement 📣 A warm welcome for our next speaker! Johan Van Weyenbergh (@johanvawe ) joins #UniteToFight2024 ! We are very happy to have you with us on this journey! 🙏 #longcovid #mecfs
If you have time to read only one thread by a Long Covid researcher today, make this be the one!
#LongCovid is complex to diagnose and treat, so we need #biomarkers! 1. to confirm viral persistence, and 2. to map the failing/overactive immune response. So we tried to hit two birds with one stone using digital transcriptomics 👇👇 (1/n) thelancet.com/journals/lanmi…
#LongCovid is complex to diagnose and treat, so we need #biomarkers! 1. to confirm viral persistence, and 2. to map the failing/overactive immune response. So we tried to hit two birds with one stone using digital transcriptomics 👇👇 (1/n) thelancet.com/journals/lanmi…
We believe clinically useful #biomarkers should be non-invasive: while it is interesting to know what happens with #SARSCoV2 in muscle or colon/gut, these biopsies are too painful and laborious to integrate in daily care for #LongCOVID patients. Hence a blood test!
This is a real-world #LongCovid cohort, based on general practice of Marc @jamoulle who has become a beacon of hope for patients in Belgium & beyond. From his practice 48 patients and 12 controls were carefully matched for age, sex, time since COVID, vaccination and comorbidities
Looking at viral RNAs above cutoff (red line below) comparing patients and controls: antisense (65% vs 25%), ORF7a (60% vs 25%), Nucleocapsid (50% vs 8%), total blood viral load (60% vs 8%). Remarkably, Spike RNA was low in all cases =infection not vaccine-derived