RZLab @RZLabKI

Roman Zubarev’s group at Karolinska Institutet focuses on Molecular Biometry using mass spectrometry for studying various processes of biomedical importance. ki.se/en/mbb/roman-z… Stockholm, Sweden Joined December 2019

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RZLab @RZLabKI

a week ago

Noise isn’t always bad! Sometimes it helps us see the unseen. 🚀 Our new preprint shows how stochastic resonance boosts single-cell proteomics signals. 👉 biorxiv.org/content/10.110… #Proteomics #SingleCell #MassSpec #Preprint

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RZLab @RZLabKI

a week ago

For decades, scientists believed that stable isotopes in our tissues reflected our diet with a small correction. Our new preprint shows it’s more complex: isotopes actively shape biology and converge in surprising ways. Read the preprint 👉 [biorxiv.org/content/10.110…] #isotopes #

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Pastel BioScience @PastelBio

2 years ago

Peptide sequencing based on host–guest interaction-assisted nanopore sensing - Nature Methods nature.com/articles/s4159… --- #proteomics #prot-paper

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RZLab @RZLabKI

2 years ago

New paper published. Hopefully our results will lead to developing novel biomarkers and therapeutic interventions against traumatic brain injury in the long run.

Saei Lab @AmirAta8

2 years ago

New paper published. Hopefully our results will lead to developing novel biomarkers and therapeutic interventions against traumatic brain injury in the long run.

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RZLab @RZLabKI

2 years ago

Check out our new work on PISA-REX for analysis of proteomes in the three dimensions of redox state, solubility and expression for target identification.

Saei Lab @AmirAta8

2 years ago

Check out our new work on PISA-REX for analysis of proteomes in the three dimensions of redox state, solubility and expression for target identification.

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Prof. Nikolai Slavov @slavov_n

2 years ago

This toy example may change how you look at tSNE & UMAP. They find clusters in the most uniform data possible.

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Saei Lab @AmirAta8

3 years ago

Our new collaborative study shows that NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell (pDC) development and functions. ROS deficiency enhances pDC generation through the AKT/mTOR pathway. insight.jci.org/articles/view/…

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Frauke Graeter @graeter_mbm

3 years ago

DOPA is just as good (or even better!) than Vitamin C - when it comes to protecting tissues from free radicals. 🛡️🔥 Proud of this largely experimental (!) work of our lab. 🎉🎉🎉 Thanks to amazing collaborators @RedoxDKFZ @RZLabKI @prisnerlab and others!

3D Matter Made to Order @Cluster3DMM2O

3 years ago

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RZLab @RZLabKI

3 years ago

New work from our lab at @karolinskainst uncovers massive solubility changes of neuronal proteins upon simulation of traumatic brain injury. #TBI #neuroscience #proteomics #TeamMassSpec

Saei Lab @AmirAta8

3 years ago

New work from our lab at @karolinskainst uncovers massive solubility changes of neuronal proteins upon simulation of traumatic brain injury. #TBI #neuroscience #proteomics #TeamMassSpec

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Bio-protocol @bioprotocolbyte

3 years ago

Happy Sunday 🙂 Please check out our new protocol - "Proteome Integral Solubility Alteration (PISA) Assay in Mammalian Cells for Deep, High-Confidence, and High-Throughput Target Deconvolution". bio-protocol.org/e4556 @RZLabKI @XuepeiZhang #proteomics #spectrometry #cells

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TopSpecMS @TopSpecMS2

3 years ago

Finally, all pieces have been put together! The #FTMS Booster is now installed in the @RZLabKI. Thank you @Spectroswiss for all the help and also for a great talk!

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RZLab @RZLabKI

3 years ago

Individual amino acid isotopic ratio measurement and peptide sequencing using only 1 μg of sample, all in one!

ACS Analytical Chemistry Journals @an_chem

3 years ago

Individual amino acid isotopic ratio measurement and peptide sequencing using only 1 μg of sample, all in one!

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TopSpecMS @TopSpecMS2

3 years ago

The Omnitrap – IMS platform has successfully been installed at KI! Thank you @Fasmatech_MS , MSvision and @RZLabKI for the great effort. Time to produce some exciting data!

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RZLab @RZLabKI

3 years ago

In our new preprint, we identify the O-glycosylated substrates of GALNT1 using versatile proteomics tools. Arguably one of the most challenging PTMs to study. We close in on a motif too.

bioRxiv @biorxivpreprint

3 years ago

In our new preprint, we identify the O-glycosylated substrates of GALNT1 using versatile proteomics tools. Arguably one of the most challenging PTMs to study. We close in on a motif too.

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RZLab @RZLabKI

3 years ago

Do you know isoaspartate acts as a molecular clock in aging? We collaborated with Prof. @CharlotteTeuni1 and Dr. Guo to test the link between isoaspartate and Alzheimer's disease etiology on A&D journal doi.org/10.1002/alz.12… @alzdemjournals @alzassociation @ISTAART