80 y.o. M, h/o basal cell carcinoma (no other cancer hx), presented with a lesion in the bladder trigone. What is your diagnosis on the transurethral resection specimen? #PathTwitter @MGBpathology @MGHPathology
Prostatic adenocarcinoma involving the bladder #GUpath ➡️Prominent nucleoli, amphophilic to pale cytoplasm ➡️Pale cytoplasm: less common compared to the more typical amphophilic cytoplasm in untreated prostate cancer ➡️No prior prostate biopsy; all previous PSA levels have been within normal limits (3.3 ng/mL, 2 yrs ago); PSA after TURBT was also normal (3.7 ng/mL) ➡️Prevalence of prostate cancer: 27% among those with PSA of 3.1 to 4.0 ng/mL (PMID: 15163773)
@MGBpathology @MGHPathology Metastatic prostatic adenocarcinoma to the inguinal fold x.com/TingZhaoPathdo…
@MGBpathology @MGHPathology Metastatic prostatic adenocarcinoma to the inguinal fold x.com/TingZhaoPathdo…
@MGBpathology @MGHPathology De novo metastatic prostatic adenocarcinoma to the femoral neck x.com/TingZhaoPathdo…
@MGBpathology @MGHPathology De novo metastatic prostatic adenocarcinoma to the femoral neck x.com/TingZhaoPathdo…
@MGBpathology @MGHPathology Adjacent low-grade, non-invasive papillary urothelial carcinoma and prostatic adenocarcinoma involving the lamina propria, which can be misinterpreted as invasive papillary urothelial carcinoma x.com/TingZhaoPathdo…
@MGBpathology @MGHPathology Adjacent low-grade, non-invasive papillary urothelial carcinoma and prostatic adenocarcinoma involving the lamina propria, which can be misinterpreted as invasive papillary urothelial carcinoma x.com/TingZhaoPathdo…
@TingZhaoPathdoc @MGBpathology @MGHPathology Dds include clear cell variant of urothelial carcinoma, prostatic adenocarcinoma grade5, metastatic RCC and paraganglioma
@TingZhaoPathdoc @MGBpathology @MGHPathology Paraganglioma
@TingZhaoPathdoc @MGBpathology @MGHPathology Involved by prostate acinar adenoCa GG5
@TingZhaoPathdoc @MGBpathology @MGHPathology Although predominantly in female, I think we need to rule out clear cell adenocarcinoma of the urinary tract.