Andrew Leduc @_AndrewLeduc
Post-doc @slavovlab Interests: Non-canonical protein sequences Protein degradation Single cell analysis andrew-leduc.github.io Boston, MA Joined February 2020-
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In addition to other cool stuff, some more nPOP multiplexed DIA data featured here, check it out!
In addition to other cool stuff, some more nPOP multiplexed DIA data featured here, check it out!
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Andrew Leduc retweeted
I started a Substack blog discussing a favorite topic: 𝐖𝐡𝐢𝐜𝐡 𝐩𝐫𝐨𝐣𝐞𝐜𝐭𝐬 𝐝𝐞𝐬𝐞𝐫𝐯𝐞 𝐨𝐮𝐫 𝐥𝐢𝐦𝐢𝐭𝐞𝐝 𝐭𝐢𝐦𝐞 ? open.substack.com/pub/nikolaisla…
Andrew Leduc retweeted
“Why cant I afford a house” *wears shirt of the guy responsible*
Genome wide perturb-seq is not a very good experiment for trying to build a realistic virtual cell model if you would like to extrapolate past knock downs
Genome wide perturb-seq is not a very good experiment for trying to build a realistic virtual cell model if you would like to extrapolate past knock downs
LLMs cannot produce text that is actually well written
Hard to balance the excitement of wanting to get a big paper out with the discipline to make sure its totally polished before sharing... Stay tuned!!
Andrew Leduc retweeted
"Tabular data" didn't make sense to me as a category. Images or text are generated in a pretty specific way, but you can put anything in a table. These points about common properties have helped me understand why the same methods might work across different tabular datasets.
Haven't been in the lab in a while, forgot how fun it can be :)
Andrew Leduc retweeted
Never cease to be funny that hypers & grifters confuse or pretend that technological capabilities that could be robustly implemented in 30 years can be successfully deployed today.
Never cease to be funny that hypers & grifters confuse or pretend that technological capabilities that could be robustly implemented in 30 years can be successfully deployed today.
Andrew Leduc retweeted
people arent gonna wanna hear this but i truly do not believe this mistake could’ve been made by someone with a phd. after going through brutal peer review several times you just stop doing stuff like this. whoever made this graph clearly has a bachelors degree. maybe a masters
people arent gonna wanna hear this but i truly do not believe this mistake could’ve been made by someone with a phd. after going through brutal peer review several times you just stop doing stuff like this. whoever made this graph clearly has a bachelors degree. maybe a masters
This dude is insufferable
Andrew Leduc retweeted
The NIH budget would INCREASE by $400m — not slashed by 40%, as Trump proposed — in a proposal by Senate appropriators, says Sen Murray. "Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yes—Congress has your back", she says.
Andrew Leduc retweeted
In this interview, I explain how university research, when funded by independent #NIH #NSF federal grants, brings oversight to biotech to fuel innovation while keeping science transparent, reliable, and in service of the public good: hub.jhu.edu/2025/07/30/jea… #ResearchMatters
Andrew Leduc retweeted
One lesson of DOGE is that a lot of federal govt spending is sent to old ppl (social security, Medicare) and affluent individuals/orgs (defense, health spending) but the spending with the highest “lives saved per dollar spent” tends to go to v poor people or to scientists working…
Andrew Leduc retweeted
Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @CellCellPress, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. sciencedirect.com/science/articl…
It's that time again, where finishing the last 5% of a paper means your productivity turns to snails pace
Andrew Leduc retweeted
@LabWelch Andrew @_AndrewLeduc talked about measuring protein synthesis and degradation rates in single cells at @SCP_meeting: youtu.be/adkY6txDyqs?si… We are working on writing up these results soon, and will be happy to share the data with you.
Andrew Leduc retweeted
Andrew Leduc retweeted
@RyanMorey Possibly. I wanted to simply clarify that in compbio the fundamental problem is often the opposite - that early researchers don't spend enough time wrangling, understanding & sanitizing raw data
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