Mike Lodato @_MikeLodato
Assistant Professor @UMassChan, father, husband, ex-jock. Owner of 100 billion mutant neurons, each with its own genome. lodatolab.org Worcester, MA Joined February 2016-
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Whitehead Institute Founding Member Rudolf Jaenisch has received the 2025 Ogawa-Yamanaka Stem Cell Prize, which recognizes his seminal role in establishing and advancing the field of induced pluripotent stem cells (iPSCs). wi.mit.edu/news/rudolf-ja… @GladstoneInst
Excited to share my lastPhD publication! We discovered non-inherited mutational patterns in schizophrenia occurring before birth. Huge collaborative effort w/ @seplyarskiy @jones_attila science.org/doi/10.1126/sc…
We are delighted to be a part of several exciting collaborative projects and are looking for a senior scientist to lead organoid generation and analysis for these projects, with room to develop independent projects as well. Please apply or share! recruit.apo.ucla.edu/JPF09796
Huge thanks to the Riccio fund and our fantastic collaborators in the Logan lab (@wickedneuro)!
Huge thanks to the Riccio fund and our fantastic collaborators in the Logan lab (@wickedneuro)!
We’re hiring! We have an open position for a Research Associate in the Lodato lab, details here ummsjobs.com/job/10361/. It’s a great opportunity to gain skills at the bench, publish some papers, and learn about brain aging and somatic mutation. Please repost!
We are entering the 7th year of our Next Generation Leaders (NGL) program! I have constantly been amazed by these NGLs - they are not only brilliant, creative scientists but also incredibly kind and genuine human being. Treasure the lasting bond with them! Hope you will join us!
We are entering the 7th year of our Next Generation Leaders (NGL) program! I have constantly been amazed by these NGLs - they are not only brilliant, creative scientists but also incredibly kind and genuine human being. Treasure the lasting bond with them! Hope you will join us!
I'm delighted to share the latest work from our lab in which @HaoChingJiang1 and SungJin Park demonstrate that MS4A1/CD20 functions as a mammalian odorant receptor in a previously uncharacterized population of sensory neurons. rdcu.be/dE8B7
@aaas @sudipsparikh Very grateful to have been chosen as a AAAS fellow this year. Of course these awards are only possible due to the enormous efforts of the many grad students and postdocs that I have been lucky to mentor over the years. Let’s all have a drink😁
Happy to share this review article on microglial phagocytosis mechanisms in development informing disease. Great collaborative effort between @becca_beiter and @patwsheehan in the lab. sciencedirect.com/science/articl…
‼️Job alert! ‼️ multiple #postdoc positions open in my lab @Princeton. Interested in single cell #genomics & brain development? #studyBRAIN projects, cell type tools for 🐒🧠, weird evolutionary phenomena (chimeric microglia??) Check us out krienenlab.org & pls RT!
📢 The Cai Lab is recruiting technicians! Neuroscience, computational, or psychology related experience is preferred. If you’re interested in joining our fun and talented team, please send an intro and CV to [email protected].
Our work about contrasting patterns of somatic mutation accumulation between oligodendrocytes and neurons in the aging human brain, is now online in @CellCellPress! Huge thanks to @sarabiz86 @JoeLuquette @peter_j_park @ChrisAWalsh1. See tweetorial (1/10). tinyurl.com/4u9fj84r
Our newest pub! snRNAseq in human and non-human primate brain reveals elevated DNA damage markers in striatum related to chronic opioid use. Led by @maddiehray and @BadoiPhan. Collaboration with @apfenning and others. Excited to have this out! nature.com/articles/s4146…
🧠 Exciting News on Alzheimer's Research! Our latest preprint co-led by @zinan_zhou and @MayaTalukdar with PIs @ChrisAWalsh1 and @EAliceLee2 delves into the mysteries of AD and unveils intriguing findings about cancer somatic mutation in microglia 🧬biorxiv.org/content/10.110…. 1/5
new preprint by Mack, Ben, and Sophia from our laboratory! targeting Endocannabinoid system may be effective for mitigating sleep alterations during opioid withdrawal. continuing to build on initial findings. @buCSNneuro @BUMedicine @UMassPsychiatry biorxiv.org/content/10.110…
Amazing work from @zinan_zhou @junhokimkr @tuihuaorjinhua @EAliceLee2 @ClotildeLagier on mosaicism in ALS/FTD. How does a mosaic mutation in <5% of cells in one region produce pathologically conventional ALS/FTD? Answers welcome!
Excited to share our preprint on brain mosaicism in sporadic amyotrophic lateral sclerosis (sALS) and frontotemporal dementia (sFTD) that implicates surprising mechanisms. biorxiv.org/content/10.110…. 1/10
Thanks @RealPatSargent and others in @UMassCommDept for highlighting our work and recent award from @ACS_Research. Very appreciative to our lab members and team @UMassChan who made this possible. We are hiring at all levels and excited to get started on this work!
Thanks @RealPatSargent and others in @UMassCommDept for highlighting our work and recent award from @ACS_Research. Very appreciative to our lab members and team @UMassChan who made this possible. We are hiring at all levels and excited to get started on this work!
Turns out development of human cerebral cortex is unlike any animal ever described! Latest work from Sonia Nan Kim (@snk_kim) and twitterless Vinay Viswanadham @peter_j_park lab, using clonal mutations and cell types sampled across human cortex. biorxiv.org/content/10.110… A thread.
Allenites are presenting 80+ posters at #SfN23! Check out the full list of posters: alleninstitute.org/events/sfn2023/ Topics include: 🧠 visual cortex 🧠 psychedelic drugs 🧠 aging 🧠 task-switching 🧠 cloud-based data processing 🧠 whole mouse brain atlases 🧠 brain clearing & expansion

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UMass Chan Medical Sc... @UMassChan
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