Hans-Christof Gasser @_hcg_
Biomedical AI student researching the application of AI to questions in immunology Joined March 2018-
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The second CAPE paper demonstrates that direct preference optimization (DPO) can be used to fine-tune ProteinMPNN to generate protein designs predicted to be less visible to cytotoxic T lymphocytes, potentially reducing their autoimmunity risk doi.org/10.1093/protei…
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In this paper you can read all about the first steps towards CAPE - a suite of tools for the integration of immune-visibility targets into the computational protein design process
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