Esther Shin @_hyejinee
HHMI/Stanford Postdoctoral associate @JacobsWagnerLab and University of Toronto PhD @moraes_lab Stanford, CA Joined May 2010-
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1/ Exploratory Data Analysis (EDA) is the first step in any data analysis journey. When working with RNA-seq data, one of the most commonly used techniques is Principal Component Analysis (PCA). But what exactly is PCA, and why does it matter? Let’s break it down. 🧵👇
Antibiotics that Kill Gram-negative Bacteria by Restructuring the Outer Membrane Protein BamA biorxiv.org/cgi/content/sh… #biorxiv_micrbio
Excited to share our new paper in @MolecularCell! We’ve developed TurboCas, a powerful new CRISPR-based proximity labeling tool that lets us pinpoint the proteins regulating gene expression at specific genomic loci. Check out what we discovered: cell.com/molecular-cell…
🫴Bacterial peptidoglycan recycling: Trends in Microbiology: cell.com/trends/microbi…
If interested in bacterial resilience or the biology of the Lyme disease agent Borrelia burgdorferi, please consider checking out our preprint. Led by talented grad student Jessica Zhang and former postdoc @NickTakacs86 in fun collab with Patti Rosa’s lab. biorxiv.org/content/10.110…
Watch how BAM and SurA fold proteins! Our cryoEM structures brought to life in this awesome animation by @phospho! Read about it in our paper published last month nature.com/articles/s4146… @RadfordLab @naranson
DNA/polysome phase separation and cell width confinement couple nucleoid segregation to cell growth in Escherichia coli biorxiv.org/cgi/content/sh… #biorxiv_micrbio
It is hard to beat nature in the design of antibiotics. In this review, we analyze the sophisticated mechanisms of many antibiotic substances with an eye toward future antibacterial drug discovery. nature.com/articles/s4158…
Phase separation as a new form of regulation in innate immunity dlvr.it/T9WQlT
Thank you! @CanLightSource Check out our story
Thank you! @CanLightSource Check out our story
Hemophores are like little bandits that some bacteria use to snatch iron from our cells. Researchers @UofTB @UofT the CLS and @advancedphoton to help study the structure and prevalence of hemophores. Full story: bit.ly/3xxS8jd #OnTheBeamlines @ASMicrobiology
Using live-cell single-molecule tracking for your experiments, but not sure which fluorescent label to use? Our new study might help! pubs.acs.org/doi/10.1021/ac…
Bacterial glycolipid acting on protein transport across membranes buff.ly/3JTFhud (@ChemBioChem)
The first Microtutor interactive virtual imaging course is now live on the @GlobalBioImage training platform! Learn fundamental principles that are critical to rigorous fluorescence microscopy experiment design. Free & open to all! Funded by @cziscience. microtutor.globalbioimaging.org
New article introduces a high precision marker-free drift correction algorithm for #SuperResolution single molecule localization #Microscopy #SMLM! Click to check it out: bit.ly/3V7reGE
Tracking gut bacterial lipids. @CMirrettaBarone Ley&Vu labs @MPI_Bio develop spatial mass spec method to track transfer of lipids from #gut #microbiome into host tissues. Uncover transfer of bacterially derived phosphatidic acid from Bacteroides into colon cell.com/cell-host-micr…
Influence of antimicrobial peptides on the bacterial membrane curvature and vice versa dlvr.it/T7Fzvh
Super excited to share our latest work on the bacterial Tol-Pal complex by the brilliant @WeeBoon5! We can (finally) confidently assign the true function of Tol-Pal in maintaining OM lipid homeostasis, independent of its role in cell division! Here's how Wee Boon did it 👇 1/7
Super excited to share our latest work on the bacterial Tol-Pal complex by the brilliant @WeeBoon5! We can (finally) confidently assign the true function of Tol-Pal in maintaining OM lipid homeostasis, independent of its role in cell division! Here's how Wee Boon did it 👇 1/7
Hello, my absolutely lovely membrane peeps! Would you maybe, pretty-please, let me proudly steer you to a MINI-REVIEW I recently wrote? It’s on asymmetric membranes in general, and differential stress in particular—subjects that I am massively interested in right now! 1/26

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