D_• @_xuwen

Whatever cannot evolve I have not created. Daydreams of redesigning our designs on Nature. Joined April 2010

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Vatsan Raman @vatsanraman

11 months ago

My PhD advisor, David Baker, just won the Nobel Prize! 🎉 He is an inspirational scientific leader who not only does groundbreaking research but has also built an enduring, supportive community. Most importantly, he’s a genuinely kind human being. Congratulations David! I am so…

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Jeff Nivala @jeffnivala

a year ago

Published today in @Nature, we describe an approach for single-molecule protein reading on @nanopore arrays. By utilizing ClpX unfoldase to ratchet proteins through a CsgG nanopore, we achieved single-amino-acid sensitivity. nature.com/articles/s4158…

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Stephen Fried JHU @fried_lab

12 months ago

There are a lot of big claims circulating these days about nanopore protein sequencing. I say we organize a CASP like competition. We send you 10 random peptides from the human proteome, you gotta guess what they are. Who wants to do this? 😀 Any foundation want to fund?

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Anders Sejr Hansen @Anders_S_Hansen

a year ago

This is an excellent review on fine-scale compartments/microcompartments and recent discoveries:

Jordan Rowley @MJordanRowley

a year ago

This is an excellent review on fine-scale compartments/microcompartments and recent discoveries:

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Jian Ma @jmuiuc

a year ago

Excited to share scGHOST, now published @naturemethods, graph-based #ML identifying #3Dgenome subcompartments in single cells. Kudos to @KyleXiongCMU & @RuochiZhang, who worked so closely on this. Exciting time for single-cell epigenomics & multiomics! nature.com/articles/s4159…

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Patrick Hsu @pdhsu

2 years ago

Who wants to combine Evo (our DNA foundation model) and bridge RNA recombinases to demonstrate genome-scale design in living cells?

Tom Ellis @ProfTomEllis

2 years ago

Who wants to combine Evo (our DNA foundation model) and bridge RNA recombinases to demonstrate genome-scale design in living cells?

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Adam Silverman @adsilverman627

2 years ago

Terrific study from the Styczynski lab, mandatory reading for anybody working in cell-free synbio! pubs.acs.org/doi/full/10.10…

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Cell Systems @CellSystemsCP

2 years ago

We asked Birte Höcker, Peilong Lu, Ora Schueler-Furman, @helloanum @deboramarks @pranamanam @SluskyLab @PossuHuangLab how the protein design community can best support biologists who want to harness AI tools for protein structure prediction and design cell.com/cell-systems/f…

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D_• @_xuwen

2 years ago

Where can I get phi174 phages for free

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D_• @_xuwen

2 years ago

Sometimes the thing that keeps me going in research is seeing ignorance in high school and undergraduate students. They don't know what works and doesn't works. They have so much energy to make mistakes that sucess is an inevitability!

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D_• @_xuwen

2 years ago

I know what to do tommorow!!!

Patrick Hsu @pdhsu

2 years ago

I know what to do tommorow!!!

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jared toettcher @toettch

2 years ago

I hope you all find OptoMBP to be useful! Kudos again to@EH_Reed, to our wonderful collaborator Kazu (@kazuhiroaokilab). OH, and the preprint is here: biorxiv.org/content/10.110… Should have said that earlier! Sigh.

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Tetsuhiro Harimoto @TetsuHarimoto

4 years ago

Thrilled to announce a new piece of my PhD work - out today @NatureBiotech! We developed a genetically-encoded encapsulation system to deliver therapeutic bacteria to tumors in mice go.nature.com/3tju12D Some highlights 🧵(1/9)

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Arvind Murugan @murugan_chicago

2 years ago

Can the intrinsic physics of multicomponent systems show neural network like computation? Out now: nature.com/articles/s4158… Led by Constantine Evans w/ Jackson O'Brien, Erik Winfree. U Chicago summary: news.uchicago.edu/story/uchicago…

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jared toettcher @toettch

2 years ago

Happy to share a new opto-technique preprint from the lab spearheaded by the indomitable @EH_Reed! In it we report a technique to dissolve constitutive protein condensates using an old friend, the classic "solubilizing" protein domain, MBP.

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Uri Manor 💔 @manorlaboratory

2 years ago

👀👀👀👀👀

myosin actin crazy @myosinactncrazy

2 years ago

👀👀👀👀👀

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The Struggling Scientists Podcast @TheStrugglingS4

2 years ago

Don't lie to me! You've thought about it too🧐

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Bento Lab 🧬 @theBentoLab

2 years ago

Here's an article that shows how (semi-) quantitative digital droplet PCR can be done using a homemade microfluidic droplet prototyping toolkit. The authors detected and roughly quantified human GAPDH RNA transcripts using standard PCR laboratory equipment - very cool! By way of…

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Patrick Hsu @pdhsu

2 years ago

this is what research feels like

trevy @chillextremist

2 years ago

this is what research feels like

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MeyerLab @MeyerLabDuke

2 years ago

Excited to share our recent work developing a genetically encoded m6A sensor. We hope this will be of widespread use for studies of m6A dynamics and high throughout applications. Very proud of the talented Fadi Marayati (@RNAloops) who led this study! rdcu.be/duW2p