Naphak Modhiran @cusycon
postdoc virologist @UQ : believes in imagination-💡 -traveller : loves nature 🏔🗻🏝🏖🛩📷 Joined March 2007-
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Naphak Modhiran retweeted
Nature research paper: One-shot design of functional protein binders with BindCraft go.nature.com/4g0R09u
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Naphak Modhiran retweeted
🔍 Look the statistics in #France regarding to #mosquito borne #arboviruses notified by the end of Aug‼️ 🦠 228 #Chikungunya cases 🦠 15 #Dengue cases 🦠 15 #WestNile human infections 🦟 #VectorControl interventions are key to reduce risks of transmission ✔️
Naphak Modhiran retweeted
Here's how to predict binding of tens or hundreds of small molecules to protein assemblies using Boltz 2 in ChimeraX. Accuracy depends on how similar the ligands and binding pockets are to existing experimental structures. rbvi.ucsf.edu/chimerax/data/…
Naphak Modhiran retweeted
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, @csche11h, @sokrypton, @befcorreia and many other amazing lab members and collaborators. nature.com/articles/s4158…
Naphak Modhiran retweeted
Identification of broadly inhibitory anti-PfEMP1 antibodies by mass spectrometry sequencing of plasma IgG from a malaria-exposed child pnas.org/doi/abs/10.107…
Naphak Modhiran retweeted
A new #ScienceReview looks at a different approach to drug discovery that may enable drugging of unconventional targets through stabilization of macromolecular complexes with molecules known as “LOCKTACs.” Learn more: scim.ag/4lAiKmF
Naphak Modhiran retweeted
Did you know amphibians and fish have viruses that are very similar to human influenza B viruses? We didn't know either, but Eddie Holmes found them and we had a closer look at their HAs and NAs. with @gabagagan @WardLab1 @RobertPdeVries1 @dishabhavsar science.org/doi/10.1126/sc…
Naphak Modhiran retweeted
Another new paper from our lab - this time from Anastasiya Kishkevich who has developed "YTK Display-and-Secrete" a library-based method to identifying genetic designs good for protein secretion from S.cerevisiae yeast. Online now at ACS SynBio - pubs.acs.org/doi/10.1021/ac…
Naphak Modhiran retweeted
Master’s student Kenya Lugo researches antigenicity of Ross River virus, w/ aims to find cross-reactive antibodies b/w wild type & chimeric virus strains. Rising outbreaks & no licensed vaccine, her work is crucial for future therapeutic developments. @JodyPeters20
Naphak Modhiran retweeted
🦠 New tool alert! Scientists developed NASPA, a rapid assay to profile antibodies that block influenza’s neuraminidase – helping track antigenic drift & guide better vaccine design. Faster, simpler, and HA-antibody–independent! 💉🔬 👉 doi.org/10.1038/s41541… #Flu #Vaccines #NA
Naphak Modhiran retweeted
ProteinGenerator simultaneously generates protein sequences and structures using sequence space diffusion go.nature.com/4gGcus0 rdcu.be/eBetI
Naphak Modhiran retweeted
Happy to share the final version of our article on the identification and characterization of novel bat coronaviruses, published in @PLOSPathogens 🦇🎉 Congrats to Claudia, first author of this paper, and all co-authors! 👏 dx.plos.org/10.1371/journa…
Naphak Modhiran retweeted
The @UWproteindesign's experimental pipeline behind models like RFdiffusion and ProteinMPNN: - A rapid, scalable, pipeline for producing and characterizing proteins - A demultiplexing protocol for converting oligopools to clonal constructs Jason Qian @LFMilles @BasileWicky
Naphak Modhiran retweeted
PepMLM is out in @NatureBiotech! 🎭Want a short binder for any target? Just input its sequence + desired binder length → PepMLM unmasks it. Simple? No way? The results speak for themselves. 👇 📜: nature.com/articles/s4158… 💻: github.com/programmablebi… 🤗: huggingface.co/ChatterjeeLab/……
Naphak Modhiran retweeted
Excited to share our new @NatureMicrobiol paper revealing the most complete arenavirus glycoprotein complex (GPC) structures to date 🤩@TheColinMann @HarvardMicro @VirologyHarvard nature.com/articles/s4156…
Naphak Modhiran retweeted
Genome-wide CRISPR screen reveals key role of sialic acids in PEDV and porcine coronavirus infections | mBio journals.asm.org/doi/10.1128/mb…
Naphak Modhiran retweeted
Out Now! Molecular organization of the New World arenavirus spike glycoprotein complex bit.ly/45vyD7L #Arenavirus #MolecularBiology #CryoEM
Naphak Modhiran retweeted
Hi everybody! I am super excited to share the work done during my PhD published in @Nature today! We describe a new mechanism of self- vs. non-self RNA discrimination by showing how N-glycans shield glycoRNAs from stimulating endosomal RNA sensors nature.com/articles/s4158…
Naphak Modhiran retweeted
Now this is big! N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs by blocking the hypermodified uracil base acp3U (which is immunostimulatory), thus pereventing RNAs from inducing acp3U-dependent innate immune activation. tinyurl.com/mrxaja37
Naphak Modhiran retweeted
Is single-molecule protein sequencing here yet? Here's a news report updating on the status quo - published in Nature Methods: nature.com/articles/s4159…
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3K Followers 733 Following Group Leader | GliaOmics Lab & GeneCore Facility | 🧬Single-Cell & Spatial Transcriptomics | 🧠 Glial Cells in Health & Disease | @IBT_CAS 🇪🇺 | ❤️ My Twins
Orm Kornnaphat Offici... @ormkornnp_ofc
56K Followers 30 Following CLOSED : Official fanbase for Orm Kornnaphat ✨ บ้านแฟนคลับหลักของ ออม กรณ์นภัส ✨@ormmormm #ormkornnaphat #ออมกรณ์นภัส #ไข่เจียวของออมเล็ต
NIAID-CREID @CREID_Network
601 Followers 0 Following The Centers for Research in Emerging Infectious Diseases Network, funded by NIH/NIAID, is comprised of 10 Research Centers and a Coordinating Center.
orm kornnaphat🌈 @ormmormm
406K Followers 64 Following ♡#ออมกรณ์นภัส #OrmKornnaphat #ไข่เจียวของออมเล็ต
Yellow4FLAVI @yellow4... @yellow4flavi
36 Followers 57 Following Deconstructing the protective immunity of yellow fever virus 17D to inform flavivirus vaccine design. Horizon Europe funded project,13 partners from 7 countries
Climate Amplified Dis... @climade_health
142 Followers 130 Following A global consortium led by the global south to study and respond to Climate Amplified Diseases and Epidemics
Varun Shanker @varunrshanker
643 Followers 403 Following @StanfordMed MD-PhD Program | Caltech '21 @caltechmten
Robert Haase @haesleinhuepf
12K Followers 4K Following #GenerativeAI, LLMs, (Image) Data Analysis, GPUs @Sca_DS / @UniLeipzig, also @NFDI4BioImage, @NEUBIAS_, @GloBIAS_ #openscience, views:mine
Amanda Hargrove @hargrovelab
3K Followers 1K Following Professor of Chemistry, University of Toronto @chemuoft @UTM_CPS Views expressed are mine alone. she/her/hers
FEBS @FEBSnews
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Matti Pronker @MFPronker
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Hongyi Xu @XUEY85
562 Followers 332 Following Senior Lecturer @ourANU , Researcher @Stockholm_Uni , Electron Crystallography, 3D ED/MicroED, cryo-EM, 🇨🇳🇸🇪🇦🇺. Views my ownTrends for United States
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