The Ward Lab @WardLab1
A structural bio lab using electron microscopes to study HIV, Ebola, Flu, Malaria, Coronaviruses, and membrane proteins. Views are our own. ward.scripps.edu San Diego Joined June 2018-
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The Ward Lab retweeted
Congratulations to new @NSF #GRFP fellows: Gabrielle in the @MGClab, Jared in the lab of Luke Lairson, @alexxsaladbar in the @LanderLab, Leigh in the @WardLab1 and Noah in the @disney_lab!
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The Ward Lab retweeted
Holding it together: Nanoparticle stabilization of LASV trimer. @bmgunn31 examines work of @AA_Lab_EPFL @WardLab1 using two-component nanoparticle strategy that enables stable trimeric presentation of #Lassavirus glycoprotein complex & induction of bnAbs cell.com/cell-host-micr…
The Ward Lab retweeted
Featured Article: Lassa GPC nanoparticles- path to a vaccine? Stabilized #Lassa virus glycoprotein nanoparticle vaccine induces potent #antibody responses in rabbits & protects guinea pigs from #Lassavirus challenge @WardLab1 @AA_Lab_EPFL Brouwer & Sanders cell.com/cell-host-micr…
Incredible work from Philip, @AA_Lab_EPFL, Rogier Sanders (@amsterdamumc) and more! Officially out in @cellhostmicrobe. We describe the presentation of Lassa GPC on nanoparticles and show it can induce neutralizing responses at a novel epitope. Full story: cell.com/cell-host-micr…
The Ward Lab retweeted
New in Science: Researchers have determined the cryo–electron microscopy structure of the hepatitis C virus E1E2 glycoprotein complex. The structure provides a blueprint for the design of vaccines and drugs that target the virus. scim.ag/jP
The Ward Lab retweeted
A new endowed fund set up by Prof. Andrew Ward is helping up-and-coming scientists from under-represented backgrounds to enroll in university without the worries of financial insecurity. Congratulations to inaugural recipient Alesandra Rodriguez magazine.scripps.edu/profiles/2022/… @WardLab1
Another malaria CSP antibody story describing the structural basis of how unique homotypic interactions in the L9 antibody result in a potent and protective phenotype! #malaria #cryoEM. Now available in BioRxiv biorxiv.org/content/10.110…
The Ward Lab retweeted
Two studies from Prof. Bill Schief’s lab & collaborators describe an approach to design a custom HIV vaccine that can coax the immune system to produce the right broadly neutralizing antibodies in a stepwise manner scripps.edu/news-and-event… @ImmunityCP @ragoninstitute @moderna_tx
The Ward Lab retweeted
And here's a short video what we're doing for a universal, variant-proof Covid vaccine, via joint efforts of immunology and structural biology, with @DennisRBurton and Ian Wilson, @WardLab1 youtube.com/watch?v=O2d8jG…
Outstanding work from @HaileePerrett and Philip Brouwer, go check out the paper and the beautiful Lassa GPC figures. Congrats to all involved!
Outstanding work from @HaileePerrett and Philip Brouwer, go check out the paper and the beautiful Lassa GPC figures. Congrats to all involved!
Beautiful work done by our Post Doc Gregory Martin and team including Jon Torres, Grace Gibson, Wilma Lee, Jeffrey Copps. 😍 #thatcryotho #malaria #cryoEM
Beautiful work done by our Post Doc Gregory Martin and team including Jon Torres, Grace Gibson, Wilma Lee, Jeffrey Copps. 😍 #thatcryotho #malaria #cryoEM
The Ward Lab retweeted
Many scientists are working toward the gold standard of infectious disease prevention: universal vaccines. But what does that mean? A quick intro! (& as always, a huge shoutout to Matt, Faith, and Drew—teamwork makes the dream work!) @scrippsresearch youtube.com/watch?v=1ROgFu…
Keep an eye out for cool science coming from the Murin lab!
Keep an eye out for cool science coming from the Murin lab!
So proud of you @HaileePerrett! Keep up the great work. We are lucky to have you.
So proud of you @HaileePerrett! Keep up the great work. We are lucky to have you.
Including lots of work from our lab members Wilma Lee and Jon Torres. nsEM getting the job done!
Including lots of work from our lab members Wilma Lee and Jon Torres. nsEM getting the job done!
Well done Alba and colleagues! @albatorrents @scrippsresearch
Well done Alba and colleagues! @albatorrents @scrippsresearch
The Ward Lab retweeted
Many months & edits later, our work on the baseline SARS-CoV-2 spike-reactive B cell repertoire is (finally!) out in @NatureComms. ⬇ Most interesting & relevant results below. It gets cool. ⬇ @vanGilsLab nature.com/articles/s4146… (1)
The Ward Lab retweeted
With the help of the very talented @julianna_han @WardLab1, we found out that this IGHV1-69/IGKV3-11 B cell pairing exclusively targets an apical S2 domain, which is normally obscured on the prefusion spike trimer but might be present in open and/or aberrant conformations. (8)
Trying something new for our lab outing! #watchout #axethrowing #badaxe
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