Gilbert Lab @gilbert_lab
The official page of the Gilbert Lab at FSU, where we are interested in the spatiotemporal control of DNA replication and genome architecture replicationdomain.com Tallahassee, FL Joined November 2018-
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@ScienceMagazine Replication timing maintains the global epigenetic state in human cells. "loss of RIF1 causes near-complete elimination of the RT program ... coupled with widespread alterations in chromatin modifications and genome compartmentalization." science.sciencemag.org/content/372/65…
Check out the new biorxiv from graduate student Dan in our lab. He has created a new method (TIP-seq) that combines all of the best aspects of various protein-DNA binding assays to achieve some of the highest resolution data available at the single-cell level.
Check out the new biorxiv from graduate student Dan in our lab. He has created a new method (TIP-seq) that combines all of the best aspects of various protein-DNA binding assays to achieve some of the highest resolution data available at the single-cell level.
High throughput genome-wide single cell protein:DNA binding site mapping by targeted insertion of promoters (TIP-seq) [Daniel Bartlett, Vishnu Dileep, Steve Henikoff, David Gilbert] biorxiv.org/content/10.110… ✅~10-fold more unique reads per single cell vs state-of-the-art methods
We cleaned up the Bush 1 mess, we cleaned up the Bush 2 mess and we will clean up this mess. Thanklessly as always!
We cleaned up the Bush 1 mess, we cleaned up the Bush 2 mess and we will clean up this mess. Thanklessly as always!
Nucleosome depleted regions are depleted of histones lol
Nucleosome depleted regions are depleted of histones lol
It’s not - don’t you know - Victor doesn’t believe in TADs!!
High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells
High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells
We are also still considering keynote speakers - so if you plan to attend and really have a leader in the field you'd like to hear speak. feel free to offer suggestions. DM me! Architecture people, please RT!
This is early - but everyone studying genome structure and function should keep this meeting on their radar: grc.org/genome-archite… As one of the Co-Chairs, I am happy to answer any questions you may have.

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