Pascal Devant @pascal_devant
Postdoc @Marsonlab @GladstoneInst @UCSF | PhD in Virology with @jkagan1 @harvardmed | Interest in Mechanistic Immunology, Cell Biology, Synthetic Biology Joined July 2021-
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Pascal Devant retweeted
#InterferonPower! Thrilled for our latest work @CellCellPress! With @dfrboehmer, we dug into tons of papers & created what we hope will be a go-to resource for immunologists & non-immunologist about type I, II, III (& IV😉) #interferons! Free link 👉 authors.elsevier.com/a/1leKGL7PXuFTj
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Pascal Devant retweeted
New review from our lab. Kudos to PhD student @SebGrant346534. 10 things you wish you knew about inflammatory caspases: a holistic review of their biochemistry, activation, and signalling - Journal of Biological Chemistry jbc.org/article/S0021-…
Pascal Devant retweeted
Everything you wanted to know about oxidized lipids & immunity, in one review. We explain how oxidized lipids impact inflammation, dendritic cells, anti-tumor immunity and more. Kudos to Joon Choi for his exceptional work. @harvardmed @BostonChildrens royalsocietypublishing.org/doi/10.1098/rs…
Pascal Devant retweeted
In January 2026, I will be joining Berkeley @UCBerkeley as an Assistant Professor in the Department of Chemical and Biomolecular Engineering, College of Chemistry @UCB_Chemistry, with exciting connections with world-class communities including the Lawrence Berkeley National…
Pascal Devant retweeted
Chris's @TheBourneImmuno paper is online now. Huge thanks to @BookerMan_PSU for coordinating this special Juneteenth issue @ACSPublications ACS Bio & Med Chem Au. Congrats to our growing lab and all who contributed. Happy 4th everyone!! pubs.acs.org/doi/full/10.10…
Pascal Devant retweeted
Congrats to Gladstone Postdoc @pascal_devant who was named a 2025 Jane Coffin Childs Fellow! #JCCFellow bit.ly/4noZSZZ
Pascal Devant retweeted
Ever wondered where NLRP3 needs to be in the cell to activate the inflammasome? Turns out, it does not really matter. Check out our latest study in @NatureComms: nature.com/articles/s4146… See 🧵👇 1/9
New insights into the noncanonical inflammasome point to caspase-4 as a druggable target Interesting perspective by Judy Lieberman, @WuLabHarvard, and colleagues @NatRevImmunol nature.com/articles/s4157…
Pascal Devant retweeted
Finally, our study on caspase-11 and its CARD-recognized molecular pattern is out in Science Advances! A small step, but we hope it opens new directions for studying caspase-11 and its ligands. 🔬🚀 #Immunology #Caspase11 #ScienceAdvances 🔗 science.org/doi/10.1126/sc…
Pascal Devant retweeted
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants nature.com/articles/s4159… @NatImmunol @sethmasters @shouya_feng
Pascal Devant retweeted
Now we know a major function of #Granzyme K is #extracellular to activate the #complement cascade. Out now @Nature from Carlos Donado and Michael Brenner. @harvardmed @BrighamWomens @Harvard_Imm nature.com/articles/s4158…
Pascal Devant retweeted
🚨New paper alert! 🚨 Our latest work in @ImmunityCP shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇 sciencedirect.com/science/articl…
Pascal Devant retweeted
Short IL-18 generated by caspase-3 cleavage mobilizes NK cells to suppress tumor growth nature.com/articles/s4159… @NatImmunol
Pascal Devant retweeted
Anyone left on Science Twitter who has spike specific CD8+ T cells? Wonder how you made them? Wonder no more. #27 @CytokineSociety @jkagan1 @Lo_Zanzi biorxiv.org/content/10.110…
Pascal Devant retweeted
Introducing Dr. Anh Cao! So proud of this outstanding scientist, who defended his thesis today. @harvardmed @Anh_Immunology
Pascal Devant retweeted
Excited to share the latest from the @MarsonLab! An investigation of context-specific gene regulation in T cells, which led to dynamic mechanisms required to control T cell rest and activation. Published today in @Nature thanks to the work of many! nature.com/articles/s4158…
Pascal Devant retweeted
De novo creation of an innate immune LPS receptor. Anh Cao identified the principles of LPS detection by caspase-11, revealing the CARD as a bipartite lipid binding module. This knowledge allowed us to convert an ancient CARD-like protein into a functional LPS receptor.
Pascal Devant retweeted
Excited to share our newly published preview in @ImmunityCP covering recent insights into IL-18 activation! There is still much to learn about the pro(domains) and conf(ormations) of IL-1 family cytokines! @julie_andries @SavvidesLab doi.org/10.1016/j.immu…
Pascal Devant retweeted
The pros and confs of IL-18 activation dlvr.it/T9ZjDn
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