Michael Matthies @progolab
Researcher at TUM in the field of Nucleic Acid Nanotechnology Joined September 2021-
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.@petr_sulc, @progolab et al. demonstrate how the presence of single- & double-stranded overhangs drive entropy-induced conformational changes in 2D #DNAOrigami #nanostructures. #oxDNA @ASUBiodesign @ASU @TUM_STS @TU_Muenchen Read: go.acs.org/bnw
A new tutorial by our student Sarah on using @ox_DNA ecosystem to simulate DNA origami: arxiv.org/abs/2409.13206 No coding needed, just web browser and your starting design file (cadnano or oxdna file format). Article also accompanied by video tutorial: youtube.com/watch?v=5-rgMe…
Special thanks to @DanGirsh for the Orb Demo, @progolab for Meta Quest Molecules, and @nadoukkadivin for The Future of Communication. Our attendees enjoyed your innovative demos at Vision Weekend Europe. Get your tickets to Vision Weekend USA: foresight.org/vw2024us/
Our cryo-EM structure of an RNA polymerase ribozyme is now available in the databank with the PDB ID 8T2P: rcsb.org/3d-view/8T2P
Come join us in Munich!
Foresight Fellow Michael Matthies presented at Vision Weekend France: Explore the world of #DNAOrigami with the new interactive molecular dynamics simulation using the #oxDNA model. x.com/petr_sulc/stat… @progolab
Foresight Fellow Michael Matthies presented at Vision Weekend France: Explore the world of #DNAOrigami with the new interactive molecular dynamics simulation using the #oxDNA model. x.com/petr_sulc/stat… @progolab https://t.co/c5krPKqKNS
Interactive #DNAnanotech design&simulation: With an AR headset from @MetaQuestVR and @ox_DNA , our new tool developed by J. Bohlin and @progolab will allow you to interact and edit simulated structure in real-time. Or play tug of war with DNA origami and your lab colleagues.
Real-Time Structural Biology of DNA and DNA-Protein Complexes on an Optical Microscope biorxiv.org/cgi/content/sh… #biorxiv_biophys
Check out our minimalist but versatile DNA nanotubes using just four DNA sequences. With custom geometry, chirality and length, they are great for nanopatterning and drug delivery. And they self-correct errors under dissipative conditions! Congrats Xin Luo, Dani Saliba, collabs!
Check out our minimalist but versatile DNA nanotubes using just four DNA sequences. With custom geometry, chirality and length, they are great for nanopatterning and drug delivery. And they self-correct errors under dissipative conditions! Congrats Xin Luo, Dani Saliba, collabs!
We introduce a new model #oxNA: it includes @ox_DNA and #oxRNA and supports creation of DNA-RNA hybrids. It reproduces basic structural, mechanical and thermodynamic properties of DNA-RNA hybrid duplexes: arxiv.org/abs/2311.07709 We show its applications to the following🧵1/3:
Future of #DNAnanotech design is in AR rather than VR. You do not want to trip over your colleague while you are viewing your latest @ox_DNA simulation in 3D. New AR setup for oxview.org, using @MetaQuestVR , is currently under development by @progolab , stay tuned
zoombya.github.io/oxJenga/ Trigger button allows rotation, squeezing the sides allows loading up the next structure. Playing with @threejs and WebXR. Webpage provides a VR view of some of the designs which were provided by the NA research community to nanobase.org
A DNA engine?! @petr_sulc @lrovigatti @progolab @SynBioBeta DNA Goes Full Throttle: The Smallest Engine You've Never Seen: bit.ly/46IrVdS
Our collaboration with Famulok lab and @NilsWalterLab is finally out in @NatureNano : A T7-polymerase powered DNA "nanoengine": a chemically powered oscillatory motion at nanoscale: nature.com/articles/s4156…
Amazing work led by Hao Liu and the ASU Lab of @petr_sulc.
Amazing work led by Hao Liu and the ASU Lab of @petr_sulc.
#SATassembly method applied to design of shape shifting materials: 3D folding shells that switch conformations with temperature: arxiv.org/abs/2310.03537
A _very initial_ version of MolecularNodes is now installable via pip. Checkout the examples linked for how you can do molecular rendering Blender and Molecular Nodes, all within your own jupyter notebooks!
A _very initial_ version of MolecularNodes is now installable via pip. Checkout the examples linked for how you can do molecular rendering Blender and Molecular Nodes, all within your own jupyter notebooks!
A very nice showcase of DNA nanotech by Pallav and the team. Currently trending on YouTube, with 3.9 million views. And features oxView.org view of the @ox_DNA design
A very nice showcase of DNA nanotech by Pallav and the team. Currently trending on YouTube, with 3.9 million views. And features oxView.org view of the @ox_DNA design
Do you work with 🧬DNA-PAINT or DNA-STED? 👉🏻We made DNA labels that are twice as bright and show lower background. How? Self-quenching of two fluorophores. Out now in @angew_chem doi.org/10.1002/anie.2… Fantastic work by a great team 🙏 (details 👇🏻)
The famed Stanford Smallville is officially open-source! 25 AI agents inhabit a digital Westworld, unaware that they are living in a simulation. They go to work, gossip, organize socials, make new friends, and even fall in love. Each has unique personality and backstory.…

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