Yanxiao Zhang @shawnzhangyx
Assistant Professor @Westlake_Uni | Interested in epigenetics, 3D genome, development, cancer and aging. zhangyxlab.github.io Hangzhou, China Joined June 2011-
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Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH authors.elsevier.com/sd/article/S00…
Very interesting findings!
We mapped chromatin & transcriptional changes across 8 brain regions, 3 ages, and both sexes in >1M cells. We find stem cell loss, TF dysregulation, heterochromatin decay & sex-specific X-chromosome changes with age Grateful to all collaborators!🥳 #SingleCell #Aging #Epigenomics
We mapped chromatin & transcriptional changes across 8 brain regions, 3 ages, and both sexes in >1M cells. We find stem cell loss, TF dysregulation, heterochromatin decay & sex-specific X-chromosome changes with age Grateful to all collaborators!🥳 #SingleCell #Aging #Epigenomics
We're incredibly excited to share our new method, Paired-Damage-seq, out @naturemethods today! This technique allows us to jointly analyze oxidative DNA damage and SSBs with RNA, all at the single-cell level (1/5). nature.com/articles/s4159…
Excited to share our latest article on the impact of intermittent fasting on hair follicle stem cells (HFSCs) and hair follicle regeneration. We found that activated HFSCs undergo apoptosis upon fasting, caused by elevated cellular ROS upon metabolic switching to utilizing fat.
Excited to share our latest article on the impact of intermittent fasting on hair follicle stem cells (HFSCs) and hair follicle regeneration. We found that activated HFSCs undergo apoptosis upon fasting, caused by elevated cellular ROS upon metabolic switching to utilizing fat.
Excited to finally share Perceptein, a PERCEPtron made of proTEINs: science.org/doi/10.1126/sc…
Finally out in @ScienceMagazine! Utilizing the cost-effective EasySci to profile 21 million single-cell transcriptomes across five life stages and diverse sexes/genotypes, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific…
Finally out in @ScienceMagazine! Utilizing the cost-effective EasySci to profile 21 million single-cell transcriptomes across five life stages and diverse sexes/genotypes, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific…
Happy to share with the world that the main body of my PhD thesis (and my rotation project) on the mechanism for replisome-mediated parental histone inheritance is published in @CellCellPress today🥰! cell.com/cell/fulltext/…
Online now! Min Jiang and colleagues study mouse models that harbor mtDNA mutations and observe that maternal age intensifies purifying selection processes and limits transmission of pathogenic mutations to offspring. (rdcu.be/dPqJY) doi.org/10.1038/s43587…
Happy to share our latest work @ImmunityCP, unveiling the plasticity of disease-associated microglia 🧵We investigated the dynamics of Spp1+ microglia during brain injury and recovery, and found •Spp1+ microglia exhibit context and age-dependent heterogeneity in neuropathology
Happy to share our latest work @ImmunityCP, unveiling the plasticity of disease-associated microglia 🧵We investigated the dynamics of Spp1+ microglia during brain injury and recovery, and found •Spp1+ microglia exhibit context and age-dependent heterogeneity in neuropathology
Research faculty member Dr. Yang Eric Li (@YangEricLi) is looking for students to join his new lab. Are you interested in #bioinformatics, #deeplearningmodels, and #singlecelltechnologies? Learn more & reach out to Dr. Li today.:neurosurgery.wustl.edu/mapping-human-…
We are hiring! If you are interested in techdev in sc multiomics, epigenome dynamics in development &aging, functional impacts of DNA damages, please contact us! jobs.silkroad.com/NYGenome/Caree…
We are hiring! If you are interested in techdev in sc multiomics, epigenome dynamics in development &aging, functional impacts of DNA damages, please contact us! jobs.silkroad.com/NYGenome/Caree…
We are thrilled to announce PRIME, a game-changing high-throughput method for characterizing DNA sequences with all possible nucleotide substitutions. We had great collaborations with @ziv_elad @yunliunc. Congratulations to the first authors @Xingjie_Ren and @HanYang_Henry!
We are thrilled to announce PRIME, a game-changing high-throughput method for characterizing DNA sequences with all possible nucleotide substitutions. We had great collaborations with @ziv_elad @yunliunc. Congratulations to the first authors @Xingjie_Ren and @HanYang_Henry!
My commentary article @Nature, a lot more work to do in the field the Chinese microbiome research in future. Mapping the Chinese microbiome: it’s time for a united effort nature.com/articles/d4158…
I am thrilled to annouce that I will join Brain Tumor Center @WashuBTC at WUSM @WUSTLmed, with a joint appointment in @WashUNeurosurg and @WashUGenetics. Can't wait to join these fantastic communities and work with amazing scientists!! sites.wustl.edu/yelilab
I am thrilled to annouce that I will join Brain Tumor Center @WashuBTC at WUSM @WUSTLmed, with a joint appointment in @WashUNeurosurg and @WashUGenetics. Can't wait to join these fantastic communities and work with amazing scientists!! sites.wustl.edu/yelilab
A personal update while working on #RNA23 badge... Excited to announce that Su Lab will open its door @UABGenetics in July! We are recruiting at all levels for anyone who is interested in RNA modifications, gene regulation, NGS analysis and cancer biology. (1/4)
Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity, Congratulations @rraviram!!! pnas.org/doi/10.1073/pn…
For years the NIH has been investigating scientists with China ties in secret, ending many careers with scant evidence of wrongdoing. But it’s been impossible to get the story out; no one ever wants to talk—until now. Astounding reporting from @jeffmervis science.org/content/articl…
So excited to share our work (cell.com/molecular-cell…). We developed a programmable RNA base editor, termed RESTART in the lab of Prof. Yi (@YiChengqi). Hoping our work will be a promising tool for therapeutics of PTC-disease. cell.com/molecular-cell…
Jian Ma @jmuiuc
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Cedric🧬➰🧬Fesc... @CedricFeschotte
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Bingfei Yu @BingfeiY
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Peter Adams🇪🇺�... @AdamsBioAging
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Joy Wu, MD, PhD @JoyYWu
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datamining-omics @DataminingO
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GigaScience @GigaScience
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Jia-Xing Yue (岳家�... @iAmphioxus
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Jiawei(Azalea) Yang @AzaleaJiawei
130 Followers 647 Following PhD Candidate @ CornellCALS @CornellMicrobio @ilanabrito123 lab. While with infinite ignorance, Intrepid to touch the unknown. Synthetic biology Gut Microbiome
Aging Congress @AgingCongress
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Lizhong Liu @LLizhong
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Genomics Proteomics B... @GPBees
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Anshul Kundaje (anshu... @anshulkundaje
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Ming "Tommy" Tang @tangming2005
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Oded Rechavi @OdedRechavi
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Jesse Dixon @Jesse_R_Dixon
999 Followers 139 Following Scientist | Assistant Professor at the Salk Institute for Biological Studies | M.D./Ph.D. from UC San Diego | Princeton Alum
Bojing Jia @BojingJia
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Rong Fan @RongFan8
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Lior Pachter @lpachter
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Jian Xu @JianXuLab
3K Followers 1K Following We are a group of scientists & physicians passionate about #epigenetics #metabolism #genomics #leukemia #hematopoiesis #erythropoiesis #cancer #stemcells
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Xiaotian Zhang @zxtzhangqian
806 Followers 1K Following Assistant professor of Biochemistry and Molecular Biology @UThealthHouston. Epi-geneticist & Hematologist. Husband of @mengyao_hu. Dad of 2. Tweets are my own.
Xiaole Shirley Liu @XShirleyLiu
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941 Followers 206 Following Machine learning for aging, spatial/single-cell omics, immunology || Incoming Assistant Professor @MIT | PhD @Stanford
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Ding Liu @dingliuabc
306 Followers 273 Following Brain explorer, global traveller, museum and art fan, a cappella singer, cool kid
Honggui Wu @Wu_Honggui
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Wei Zhou @Wei_Zhou_1989
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258 Followers 200 Following Assistant Professor@Westlake University | PI of Functional Lipidomics&Metabolic Regulation Lab | Cancer Biology | Lipid metabolism | Opinions are my own
American Aging Associ... @americanaging
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Gladyshev Lab @gladyshev_lab
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Yejing Ge @yejingge
384 Followers 434 Following Using skin as a model, the Ge Lab exploits mouse genetics and functional genomic approaches to study human diseases including cancer and aging.
Kejun (Albert) Ying @KejunYing
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José Pedro Castro, P... @JPCastro_Aging
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160 Followers 252 Following PhD Student @JoeEcker lab, @salkinstitute
Jingtian Zhou @zhou_jingtian
598 Followers 159 Following
Kaijin Chen @KaijinChen
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707 Followers 819 Following Assistant Professor@Duke #compbio #machinelearning #genomics👩🔬 💻 Duke SoM Neurosurgery, Biostat&Bioinfo. Alumni UIUC/DFCI/Harvard. Recruiting ML/AI4Genomics
Zepeng Yao @ZepengYao
123 Followers 139 Following Neuroscientist and Assistant Professor @UFBiology, formerly @berkeleyMCB @UMich_MCDB @Tsinghua_Uni
Wenming Huang @WenmingAGE
75 Followers 42 Following
Siyao Wang @SiyaoWang1005
114 Followers 80 Following Junior group leader at IMB @imbmainz and IGSAD #Epigenetics #Celegans #DNAdamage #Aging
Björn Schumacher @schumacherbj
19K Followers 2K Following I'm a scientist 👨⚕️, author 📕and chair for genome stability in aging and disease at the University of Cologne
Lei Li @LeiLi_bioinfo
637 Followers 692 Following PI, Computational and Disease Genomics, Bioinformatics, Genetic diseases, Single Cell
SaiFeng Cheng @SaiFeng_Cheng
169 Followers 381 Following Assistant Professor @Westlake_Uni. Postdoc with the Stelzer lab @WeizmannScience/ DNA methylation/single cell/cell fate
Xiao Tian @XiaoTianPhD
313 Followers 198 Following Assistant Professor at Sanford Burnham Prebys. Study aging mechanisms and how aging leads to diseases @sbpdiscovery
Xiao Wang @WangXiaoLab
6K Followers 507 Following Associate Professor at MIT Chemistry and Core Member at Broad Institute of MIT and Harvard
Yongdeng Zhang @YongdengZhang
663 Followers 629 Following PI at Westlake University, China. Microscopist, biophysicist, super-resolution microscopy. Opinions expressed over Twitter are mine.
Hailing Shi @HailingShi
432 Followers 221 Following Assistant Professor, Human Genetics @EmoryMedicine | PhD @UChiChemistry | HHWF Postdoc Fellow @broadinstitute @ChemistryMIT | Spatial -Omics | RNA biology
Sai Ma @saima_lab
992 Followers 408 Following Assistant Professor @MountSinai || Buenrostro Lab and Regev Lab Alumni || @Broad || @Harvard || single-cell omics || gene regulation
Teng Gao @tGaoTeng
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Zibo Chen @ZiboChen
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