Benjie Smith @smithbenjie
MD/PhD student at Stanford. Glycobiology. Immunology. Chemistry. Radiology. bit.ly/3QWk9F6 Stanford, CA Joined July 2013-
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Benjie Smith retweeted
Out today in @ScienceMagazine: Seeing glycans attached to proteins and lipids - at the *single molecule level*! 🎉🎉🎉 doi.org/10.1126/scienc… #ScienceResearch #glycotime #teammassspec My 1st #tweetorial🧵(1/n) 👇👇👇
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Benjie Smith retweeted
Excited to share our work on TAPIR, a generalizable ML model that can predict TCR-target interaction! T-cell receptors (TCRs) are involved in most diseases, but linking their sequences with targets is an unsolved grand challenge in the field. biorxiv.org/content/10.110…
It was an honor to have you hood me x2 and learn from you during my PhD @CarolynBertozzi. Your commencement speech was fantastic, complete with wisdom from your own experience and the infamous Walter White!
Benjie Smith retweeted
Happy to share the newest paper from our lab. Led by technician extraordinaire Aidan Tousley (soon to be an MD/PHD student!), this manuscript details our attempts to reimagine the structure of CARs to improve their specificity and efficacy. rdcu.be/c7avS
Woke up to incredible news this morning. Congratulations @CarolynBertozzi!!
Woke up to incredible news this morning. Congratulations @CarolynBertozzi!!
A beautiful piece on dealing with death and loss by @tpjmd “Shared presence - really being there with and for each other - at a moment of loss can sanctify sorrow. Some alchemy can wring from the stone of shared suffering something like love.” mercurynews.com/2022/02/03/893…
Benjie Smith retweeted
My lab at Stanford is hiring. We work on engineering new cancer immunotherapies and understanding their activity in early phase trials. Open postdoc positions as well as a technician with animal experience. Contact me if interested! Please retweet!
Benjie Smith retweeted
Happy to share our lab's first manuscript. In work led by @JTheruvath_MD, we tested a combo of FDA approved anti-GD2 with blockade of CD47, a macrophage checkpoint. Blocking CD47 unleashes patients' macrophages to phagocytose or 'eat' cancer cells. Combo was highly effective! 1/
Happy to share our lab's first manuscript. In work led by @JTheruvath_MD, we tested a combo of FDA approved anti-GD2 with blockade of CD47, a macrophage checkpoint. Blocking CD47 unleashes patients' macrophages to phagocytose or 'eat' cancer cells. Combo was highly effective! 1/
Benjie Smith retweeted
If anyone out there is doing glyco work with Illustrator, I have something for you! It’s a library of glycans for dropping into whatever you’re working on, as well as the SNFG colour palette. If you follow the lib, you can get updates as I make them! shared-assets.adobe.com/link/c775cc23-…
"Importantly, while screening multiple mice in parallel increases the power to discover significant hits, a single mouse is sufficient to identify significantly enriched and depleted genes."
"Importantly, while screening multiple mice in parallel increases the power to discover significant hits, a single mouse is sufficient to identify significantly enriched and depleted genes."
Benjie Smith retweeted
Calling all #glycotime fanatics! I'd like to introduce you to the #mucinome! We can now selectively enrich proteins that have mucin domains, and we developed a mucin candidacy algorithm (@riley_nm1) to assign confidence to our hits. @CarolynBertozzi 🧵👇biorxiv.org/content/10.110…
It's 2021 and cultures, which take weeks, are still the gold standard for TB diagnosis. This is another step toward solvatochromatic probes becoming the standard of care @mkamariza2002 and @Peyton_Shieh
It's 2021 and cultures, which take weeks, are still the gold standard for TB diagnosis. This is another step toward solvatochromatic probes becoming the standard of care @mkamariza2002 and @Peyton_Shieh
Congrats @KayvonPedram, excited to see what you work on next!
Rotational Block Isolation as a model for minimizing infections during re-opening. Also an explanation for why SIP orders allow small gatherings of kids in stable groups
Rotational Block Isolation as a model for minimizing infections during re-opening. Also an explanation for why SIP orders allow small gatherings of kids in stable groups
Benjie Smith retweeted
The Anatomy Lesson, 2020
Check out @CJCambier's new paper showing that a mycobacterial lipid spreads from bacteria to host to promote virulence. What's maybe creepier is that lyophilized bugs are still viable. Who knew that mycobacteria are like tardigrades? biorxiv.org/content/10.110…
A great overview of glycosyltransferases from Robert Haltiwanger. Hopefully we’re moving toward improved inhibitor design and better substrate predictions. Check it out: nature.com/articles/s4158…
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