Thijs Kuiken @thijskuiken
Professor of Comparative Pathology. Avian influenza and other emerging infectious diseases. One Health. Rapid transition to a sustainable society. erasmusmc.nl/viroscience/ Rotterdam, The Netherlands Joined May 2010-
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The world’s fastest-growing poultry markets are South Asia and Southeast Asia, with a combined total growth forecast of 30% between 2023 and 2030, according to a recent Rabobank report. #poultry #markets ow.ly/umBp50RsPaS
High levels of resistant E coli found in uncooked meat, raw dog food Uncooked chicken had the highest levels of antibiotic-resistant E coli, with similar levels found in chicken-based raw dog food. ow.ly/s1gT50RsVOz
USDA to test ground beef samples for H5N1 traces as more poultry outbreaks reported Dairy cows make up an estimated 6.8% of US beef production. ow.ly/IQ7G50RsW95 Photo: Artizone/Flickr cc
H5N1 in dairy cattle...we need to dump milk from infected cattle (and maybe the herd). Simple, eh? Not so much. How do we dispose of large volumes of infected milk on farms? Manure pits, pasteurization, ship it away (where?)...what can be done?👇 wormsandgermsblog.com/2024/04/articl…
Bird flu may infect cows outside the US, says WHO. #vogelgriep reuters.com/business/healt…
Bird flu cases are likely being missed in dairy workers, experts say. #vogelgriep nbcnews.com/health/health-… via @NBCNews
Answers, or at least replies, to less frequently asked questions about highly pathogenic avian influenza H5N1 in dairy cows; posed by @HelenBranswell and @MeganMolteni in @statnews. #vogelgriep
Answers, or at least replies, to less frequently asked questions about highly pathogenic avian influenza H5N1 in dairy cows; posed by @HelenBranswell and @MeganMolteni in @statnews. #vogelgriep
Excited to share our new pre-print regarding influenza H5 detection in wastewater in areas with avian influenza outbreaks: medrxiv.org/content/10.110… It's always a privilege to work on timely science!
Uitgebreide interview van @HelenBranswell van @statnews met verschillende onderzoekers over de uitbraak van hoog-pathogene vogelgriep in melkvee in de V.S. statnews.com/2024/04/29/bir…
It's starting to look like pasteurization inactivates #H5N1 #birdflu viruses in milk. But people who drink raw milk are playing with fire right now. statnews.com/2024/04/29/bir…
“Expect the Unexpected” For #H5N1 virus, critical not to make assumptions based on seasonal flu. Insist on data & transparency. Great piece @HelenBranswell @thijskuiken @JurgenRicht Dr. Webby @florian_krammer @statnews statnews.com/2024/04/29/bir…
@thijskuiken in This Week in Virology, Vincent Racaniello says that he had visited Ohio farmers, and said that farm workers were getting specifically conjunctivitis rather than respiratory infections. He mentioned this really casually. podcastaddict.com/this-week-in-v…
@RickABright It's within 6 mo of infection, so theoretically we could test cows for antibodies and see which have been through the infection (and hopefully now have immunity) and which haven't. If the cows haven't been mix-and-matched too much, probably a rep sample from the herd would do.
@RickABright Bulk tank milk is collected from all lactating cows multiple times a day. Samples are collected by certified samplers for antibiotics (betalactams) and other quality parameters. The highest concentration of HPAI virus is in milk. This is a simple cheap sensitive surveillance tool
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You must not say that nothing has been learned from the current pandemic after all, at 33 dairy farms only 23 people have been tested for avian influenza which clearly demonstrates that from the current pandemic we have learned that if you don’t look for it you won’t find it.
@thijskuiken Thank you from a layperson who’s been asking these same questions.
@j74205 @thijskuiken the text of that paper is a little misleading (or at least unhelpful) - its completely true the cattle viruses do contain those mutations, but so do all the recent avian 2.3.4.4bs (so its not an adaptation to cattle, its just mutations that are already widespread in the birds)
PRE-PRINT (nuevo,por revisar por pares) "Muestra mutaciones en #ProteínaDeUnión (a Célula,H=H5)..."☹️ #VirusDeGripeAH5N1 Clado 2.3.4.4b ➡️🐄Vacas lecheras #GripeAH5N1 #H5N1 #InfluenzaAH5N1 #FluAH5N1 Thank you for sharing, Dr. Thijs Kuiken @thijskuiken x.com/thijskuiken/st…
Preprint “ Highly pathogenic avian influenza A (H5N1) clade 2.3.4.4b virus detected in dairy cattle”. These viruses show mutations in the attachment protein, hemagglutinin, that are important for the virus to become efficiently transmissible among people. sciencedirect.com/science/articl…
H5N1 🦠 ‘Prevention is better than cure’
@CaringDoctors @lucasgonzalez That is the scenario for the start of a virus epidemic, or even pandemic. So it is much better to take appropriate measures in time and not let that happen! “Voorkómen is beter dan genezen.”
and not just because of proximity. Because it looks like the US situation is broader and more longstanding than first thought If it was spreading for a while before they knew, it could be doing the same here. Bulk tank testing is a first step (low sensitivity but an easy start)
Is @InspectionCan contemplating systematic surveillance for highly pathogenic avian influenza H5N1 virus in bulk milk tank samples collected by milk processors? That would make sense given the proximity of affected farms in the USA. #vogelgriep x.com/meghandavisdvm…
@JanetDaly5 @thijskuiken 3 … press release today
I’ve been deep diving into TB natural history lately, and I wanna say “hell yeah!” about pathologists. We can do really cool stuff today, but there’s nothing like the information richness of “I’ve counted bacteria and described morphology under 10 thousand microscope fields.”
Interview with Barb Petersen, at the forefront of the highly pathogenic avian influenza H5N1 outbreak in dairy cattle. She said nice things about pathologists. (Conflict of interest: I am a pathologist.) This is what she said ... 1/5 #vogelgriep @ACVP bovinevetonline.com/news/industry/…
@thijskuiken Current rearing practices are only an accelerator The main pb is that we don't seem to change course
and reassortment/evolution might happen with more spillovers into species different from birds and cows this is something to be watched closely thx to @thijskuiken for all the work @shay_fleishon @PeacockFlu @siamosolocani 2/2
@luchoogenstein @thijskuiken @vogelnieuws Dit was een van de aanvallen. Een aantal uren eerder deed ze dit ook al. Vorig jaar had een slechtvalk ook zulke symptomen in de kast bovenop ASML. Zij stortte ook naar beneden. Zij is getest en bleek vogelgriep te hebben.
@thijskuiken What about some care for ppl exposed????
@thijskuiken @US_FDA I’m not saying pasteurized milk isn’t safe to consume, but important to note: • FDA saying the milk supply is safe w/o providing supporting data (1mo after the outbreak was detected) doesn’t inspire the greatest confidence. Hope to have those studies very soon. #H5N1 #HPAI
@thijskuiken @US_FDA My Sincere Apologies! - I misread that! Thanks for your reply. Appreciate your work, and providing real communication in this space.
@thijskuiken Good article, thanks! We just had a dramatic pandemic and now this scare, how long until truly one health approaches are commonplace within gov agencies? There are timid attempts and ineffective initiatives but I don’t know of any country where the approach is taken seriously.
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