Cell Design Institute @UCSF @CDI_UCSF
Official Account of the Cell Design Institute @UCSF. Bringing a unique foundational approach to cell therapies. celldesigninstitute.org San Francisco, California Joined January 2021-
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Strongly recommend listening to this talk by Wendell Lim - very good overview of how we might engineer immune system 🦠and development 🐣 Generative biology: Learning to program cellular machines. youtu.be/0oG7OMbSWZQ?si…
Check out the latest from CDI: "Small molecule and cell contact-inducible systems for controlling expression and differentiation in stem cells" Led by Sarah Soliman @ssssoliman and Zara Weinberg @weinberz!!!
Check out the latest from CDI: "Small molecule and cell contact-inducible systems for controlling expression and differentiation in stem cells" Led by Sarah Soliman @ssssoliman and Zara Weinberg @weinberz!!!
So excited to share our preprint from the El-Samad lab on engineering multiple small molecule and cell contact-inducible systems for controlling gene expression and differentiation in mESCs! biorxiv.org/content/10.110…
So excited to share @ssssoliman’s new inducible systems for controlling mESC behavior! Sarah built these systems as a stepping stone to studies of tissue organization, but as our neighboring labs began to make use of these tools we knew it was time to share them with the world!
So excited to share @ssssoliman’s new inducible systems for controlling mESC behavior! Sarah built these systems as a stepping stone to studies of tissue organization, but as our neighboring labs began to make use of these tools we knew it was time to share them with the world!
The latest from CDI: Degron-based bioPROTACs for controlling signaling in CAR T cells! Led by Matthew Kim of the Hana El-Samad and Andrew Ng labs! Check it out on @biorxivpreprint. @HanaScientist @andrewng_synbio biorxiv.org/content/10.110…
Check out this amazing work from my labmate Matt Kim! He developed a protein degradation system that works in primary T cells to control the activity of chimeric antigen receptors and endogenous proteins! @HanaScientist @andrewng_synbio @CDI_UCSF biorxiv.org/content/10.110…
🚨New Preprint🚨 We developed targeted protein degraders to degrade CARs and endogenous signaling molecules in T cells. The genetically encodable nature of these bioPROTACs enabled us to build a circuit to degrade ZAP70 and inhibit signaling in an antigen-dependent manner.
Exciting new work from Matthew Kim @CDI_UCSF: Genetically encoded 'bioPROTACs' for antigen-inducible, targeted degradation of key signalling molecules in CAR-T cells. Delighted to be a part of this team! @andrewng_synbio @HanaScientist biorxiv.org/content/10.110…
Come join our team @CDI_UCSF!
There’s an excellent opportunity for a pre-PhD scientist to work with Wendell Lim’s team at CDI. The learning/training environment at CDI is amazing and the CDI team interacts a lot directly with Wendell’s lab at UCSF.
There’s an excellent opportunity for a pre-PhD scientist to work with Wendell Lim’s team at CDI. The learning/training environment at CDI is amazing and the CDI team interacts a lot directly with Wendell’s lab at UCSF.
Please RT! We are hiring Junior Specialists (pre-PhD level) for variety of cell engineering and synthetic biology projects. Our trainees have gone on to PhD, MD, and industry positions at @UCSF, @Harvard , Lyell, @sonomabio, @genentech, @ArsenalBio, etc! aprecruit.ucsf.edu/JPF04850
Awesome talk from CDI / Lim Lab member An Tran!
Finally said goodbye to SF after 7 years! Such a great time at UCSF, being hugely supported by so many mentors #Tejal #Tang #Wendell @TejalADesai @Tang_Lab_UCSF @CDI_UCSF and collaborators! Great that the collaborations stay, but I will miss you very much!
Damon Runyon has announced its 2023 Quantitative Biology Fellows, three exceptional early-career scientists who are applying the tools of computational science to generate and interpret cancer research data at extraordinary scale and resolution.
Youngmu (Nick) Shin, PhD, plans to explore the general principles of cell-cell communication by constructing a synthetic synapse, which may shed light on immune cell recognition of cancer cells and mechanisms of metastasis.
Congratulations to Lim Lab postdoc Dr. Nick Shin, who was just selected as a 2023 @DamonRunyon Quantitative Biology Fellow!!!
Congratulations to Lim Lab postdoc Dr. Nick Shin, who was just selected as a 2023 @DamonRunyon Quantitative Biology Fellow!!!
We are hiring! CDI is looking for a Junior or Assistant Specialist to work in the Lim Lab. Apply here: aprecruit.ucsf.edu/JPF04483
Mo Khalil @MoKhalilLab
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8K Followers 4K Following News from Dr. Alex Marson's lab @UCSF & @GladstoneInst, focusing on advances in immunology, CRISPR & genomics. Tweets represent personal views only.Justin Eyquem @j_eyquem
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2K Followers 1K Following scientist, assistant prof @stanford, co-founder @clubescienciamx and @scienceclubsint, @ucsf postdoc, @harvard grad, timbero, oaxaqueñoNish Reddy @NishRReddy
352 Followers 1K Following Systems + Synthetic Biologist | Engineering biology to understand it and treat disease. PhD in Wendell Lim’s lab @UCSF, @BerkeleyBioEHana El-Samad @HanaScientist
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588 Followers 5K Following interested in #biomaterials #tissueengineering #regenerativemedicine #medicaldevice #stemcelltherapies #T1DMinh Le @minh_science
75 Followers 336 Following @UCSF Biophysics graduate student • he/him • @UCSanDiego '22Jeanne Mitro @jea_mitr
68 Followers 5K FollowingMichaela Hinks @MichaelaThinks
550 Followers 1K Following soon to be building an AI scientist at @FutureHouseSF | formerly PhD with @BintuLab and @WJGreenleaf at Stanford | views/opinions my ownVitalii Kleshchevniko.. @vitaliikl
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106 Followers 554 Following graduate student @UCSF @aydoganlab | dev + stem cell bio | violist, music & film nerd | she/her 🇸🇬 @ASTARsgswathi v c @swathicsekhar
16 Followers 137 Following Be kind. Have grace. Give thanks. Speak love.... & stay swaggy.Janhavee Shinde @SJanhavee
61 Followers 2K FollowingUmasish Mohanty @Mohanty_immuonc
73 Followers 296 Following PhD research fellow at @ACTREC_TMC :: CAR T cell therapy enthusiast :: Viral vectors :: Assay development :: Cell line development ::Umair Hassan @neuro_engineer
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37 Followers 165 Following Postdoc @YaleMed | 🎓 @OKState | Microbiome, CVDs, T1D, Gut Mucosal Immunology | Opinions are mineKazuhito Morioka, MD,.. @KazuhitoMorioka
1K Followers 6K Following Assistant Professor @ UCSF Orthopaedic Surgery 🇺🇸 整形外科専門医・医学博士 🇯🇵 / 海外日本人研究者ネットワーク(UJA)理事 / DOCSF JAPAN Co-Chair / Focus Academy Faculty / 在外公館 科学技術フェロー🏈49Alessio Mallozzi @AlessioMallozzi
134 Followers 353 Following Synthetic Biology PostDoc @Tigem_Telethon. Provo a far ragionare complottisti su tesi antiscientifiche finché non mi stanco e li insulto.Oguzcan @oguzcannates
15 Followers 57 FollowingPrecision Medicine Wo.. @PMWCintl
5K Followers 3K Following Leading precision medicine forum hosting the latest initiatives in #healthcare & #biotech, est. 2009 Register for PMWC Feb5-7: https://t.co/iRs7K0eAOz柳染 @Liuran_jyz
310 Followers 2K Following Undergraduate Student |Bioscience 🧬|Synthetic Biology|Astronomy | ex-OIer|INFJ|HAM|Film|唯自由与勇气永存 | he/him/his | English /中文/簡単な日本語 OKWafa Alhajjar, PhD @WAHPersonal
168 Followers 943 Following assistant professor, VC scientific consultant, postdoctoral fellow @harvardmed and @MGH_RI.Shohini Maitra @ShohiniMaitra
43 Followers 187 FollowingEstefania Sanchez-Vas.. @NiaSanchezV
1K Followers 3K Following Postdoctoral scholar in Dev & Stem cell-BME / IRACDA fellow / Advocate for DEI in science GSA #ucsc ️🌈 UNMSM 🇵🇪 UNSAM 🇦🇷Chance Bowman @Chance_Bowman6
218 Followers 552 Following Incoming BioEngineering PhD Student @UCSF / @UCBerkeley | @dartmouth 23' | Interested in Stem Cells & Muscle BiologyFiona Qu @fiona__qu
6 Followers 103 Following PhD student @harvard in @deboramarkslab - excited about computational models for proteinsTing-Wei Liao @TingWeiLiao2
243 Followers 673 Following Passionate Ph.D. candidate in @taekjip lab @BostonChildrens | PCMMGang Xue | 薛刚 @gangxue0502
133 Followers 634 Following 5th-year Ph.D. candidate at @PKU1898 (looking for postdoc) | Systems Biology, Cell Fate Decisions and Gene Regulatory Network | B.S. UCAS @UCAS1978Haopeng Wang @HaopengWang_Lab
100 Followers 213 Following Associate Professor at ShanghaiTech University, focusing on the design of CAR-T, CAR-NK, TCR-T, and Regulatory T-cell therapies #Immunotherapy #CellTherapyherman_tx @herman_tx
3 Followers 64 FollowingMo Khalil @MoKhalilLab
8K Followers 2K Following Prof. @ Boston University and Wyss Institute. Understanding the natural world by building a synthetic one. website: https://t.co/PyjGQRHoUyKyle G Daniels @ScienceKyle
2K Followers 1K Following Assistant Professor @Stanford University Genetics. Synthetic Biologist // Real Human 🧬 🔬 💻 🏳️🌈 🏊🏾♂️Marson Lab @MarsonLab
8K Followers 4K Following News from Dr. Alex Marson's lab @UCSF & @GladstoneInst, focusing on advances in immunology, CRISPR & genomics. Tweets represent personal views only.Science Magazine @ScienceMagazine
4.0M Followers 483 Following The world's leading outlet for cutting-edge research in all areas of science. Follow @NewsfromScience for stories from our news team.Justin Eyquem @j_eyquem
1K Followers 437 Following Eyquem_Lab / Gene Editor and Synthetic Immunologist @UCSF. Investigator @GladstoneInst and @ParkericiKole Roybal @KoleRoybal
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2K Followers 1K Following scientist, assistant prof @stanford, co-founder @clubescienciamx and @scienceclubsint, @ucsf postdoc, @harvard grad, timbero, oaxaqueñoNish Reddy @NishRReddy
352 Followers 1K Following Systems + Synthetic Biologist | Engineering biology to understand it and treat disease. PhD in Wendell Lim’s lab @UCSF, @BerkeleyBioEHana El-Samad @HanaScientist
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2K Followers 632 Following PI & Director of @altos_labs Comp Bio. Cell engineer @c3stc - ex @IBMresearch Almaden | father of 👬🏼🇮🇹 MC Hammer follows me. [email protected]Parker Institute for .. @parkerici
11K Followers 682 Following Our mission is to accelerate the development of breakthrough immune therapies to turn all cancers into curable diseasesLukasz Bugaj @BugajLab
1K Followers 725 Following Asst. Professor @ Penn Bioengineering. Cell Signaling, optogenetics, synthetic biology, cancer signaling, regenerative medicine, bio-tinkering.Adam Stevens @stevenschem
232 Followers 203 Following Hartz Cell Design Institute Fellow at UCSF interested in protein engineering, synthetic biology, and cell adhesion.nature @Nature
2.6M Followers 4K Following Research, News, and Commentary from Nature, the international journal of science. For daily science news, get Nature Briefing: https://t.co/wGmQlQ8a4Dzara weinberg 🧪�.. @weinberz
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29 Followers 253 FollowingXiao Huang 黄潇 @XiaoHuangNano
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134 Followers 209 Following UCSF Postdoc, Helen Hay Whitney Fellow #SyntheticBiology #Epigenetics #Immunotherapyjared toettcher @toettch
2K Followers 626 Following Dad, cell biologist, climber, skier, surfer (in that order, more or less). Chaotic good alignment, or so my lab tells me...IOTN Moonshot @IOTNmoonshot
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60 Followers 211 Following Synthetic immunologist building therapies for 🧠 diseases. Postdoc at UCSF in Wendell Lim’s lab. PhD work with Andrew DillinJimmie Ye @yimmieg
3K Followers 171 Following Professor @ UCSF, Genomicist, Geneticist, Adopted Immunologist, #GirlDad, ImmigrantUC San Francisco @UCSF
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16K Followers 442 Following Accelerating science & developing new technologies to help cure, prevent, or manage all disease. Locations: #CZBiohubSF, #CZBiohubCHI & #CZBiohubNYUCSF Bakar ImmunoX In.. @immunox
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1K Followers 249 Following cells and proteins. molecular machines. Assistant Professor: @uwbiochem | Postdoc: @stanford @prakashlab | Ph.D.: @ucsf Wendell Lim @CDI_UCSFValhalla Foundation @ValhallaFound
314 Followers 57 Following Our focus areas are early childhood development, K-12 education, data science, medical research, environmental innovation, and collaborative philanthropy.Josiah Gerdts @jkgerdts
28 Followers 29 Following Neurologist-Scientist at UCSF, synthetic biologist in Lim LabHersh Bhargava @HershBhargava
675 Followers 2K Following computational + synthetic biology → cell engineering // biophysics PhD candidate @UCSF (Lim & El-Samad Labs) // DoD NDSEG fellow // co-founder @skolayofficialWallace Marshall @WallaceUcsf
10K Followers 5K Following professor at UCSF, engineer turned cell biologist, wants to know how cells solve geometry problemsDaniel Bryan Goodman @dbgoodman
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202 Followers 66 Following Synthetic, systems, and computational immunologist. Cell therapy @UCSFTejal A. Desai @TejalADesai
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2K Followers 2K Following Synthetic developmental biologist that want to learn how to use nature’s masterpiece of embryonic development to build tissues - and run a healthy labStrongly recommend listening to this talk by Wendell Lim - very good overview of how we might engineer immune system 🦠and development 🐣 Generative biology: Learning to program cellular machines. youtu.be/0oG7OMbSWZQ?si…
So excited to share our preprint from the El-Samad lab on engineering multiple small molecule and cell contact-inducible systems for controlling gene expression and differentiation in mESCs! biorxiv.org/content/10.110…
So excited to share @ssssoliman’s new inducible systems for controlling mESC behavior! Sarah built these systems as a stepping stone to studies of tissue organization, but as our neighboring labs began to make use of these tools we knew it was time to share them with the world!
So excited to share our preprint from the El-Samad lab on engineering multiple small molecule and cell contact-inducible systems for controlling gene expression and differentiation in mESCs! biorxiv.org/content/10.110…
Congrats to Sarah @ssssoliman on her first-first author paper and Zara @weinberz on her first-last author paper!!!
So excited to share @ssssoliman’s new inducible systems for controlling mESC behavior! Sarah built these systems as a stepping stone to studies of tissue organization, but as our neighboring labs began to make use of these tools we knew it was time to share them with the world!
Congratulations to my lab mate Matt Kim!
The latest from CDI: Degron-based bioPROTACs for controlling signaling in CAR T cells! Led by Matthew Kim of the Hana El-Samad and Andrew Ng labs! Check it out on @biorxivpreprint. @HanaScientist @andrewng_synbio biorxiv.org/content/10.110…
Check out this amazing work from my labmate Matt Kim! He developed a protein degradation system that works in primary T cells to control the activity of chimeric antigen receptors and endogenous proteins! @HanaScientist @andrewng_synbio @CDI_UCSF biorxiv.org/content/10.110…
🚨New Preprint🚨 We developed targeted protein degraders to degrade CARs and endogenous signaling molecules in T cells. The genetically encodable nature of these bioPROTACs enabled us to build a circuit to degrade ZAP70 and inhibit signaling in an antigen-dependent manner.
Exciting new work from Matthew Kim @CDI_UCSF: Genetically encoded 'bioPROTACs' for antigen-inducible, targeted degradation of key signalling molecules in CAR-T cells. Delighted to be a part of this team! @andrewng_synbio @HanaScientist biorxiv.org/content/10.110…
There’s an excellent opportunity for a pre-PhD scientist to work with Wendell Lim’s team at CDI. The learning/training environment at CDI is amazing and the CDI team interacts a lot directly with Wendell’s lab at UCSF.
Please RT! We are hiring Junior Specialists (pre-PhD level) for variety of cell engineering and synthetic biology projects. Our trainees have gone on to PhD, MD, and industry positions at @UCSF, @Harvard , Lyell, @sonomabio, @genentech, @ArsenalBio, etc! aprecruit.ucsf.edu/JPF04850
Finally said goodbye to SF after 7 years! Such a great time at UCSF, being hugely supported by so many mentors #Tejal #Tang #Wendell @TejalADesai @Tang_Lab_UCSF @CDI_UCSF and collaborators! Great that the collaborations stay, but I will miss you very much!
Super excited to attend the 72nd Lindau Nobel Laureate Meeting thanks to the @UofCalifornia President's Fellowship @UCSF @UCSFGradDiv !! #LINO23 @lindaunobel graduate.ucsf.edu/news/ucsf-lind…
new paper alert: "Light-switchable transcription factors obtained by direct screening in mammalian cells", work by badass grad student @LiyuanZhu7. One question that motivates a lot of our work in the lab at the moment: how can we make cellular optogenetics as general as GFP?
Damon Runyon has announced its 2023 Quantitative Biology Fellows, three exceptional early-career scientists who are applying the tools of computational science to generate and interpret cancer research data at extraordinary scale and resolution.
Youngmu (Nick) Shin, PhD, plans to explore the general principles of cell-cell communication by constructing a synthetic synapse, which may shed light on immune cell recognition of cancer cells and mechanisms of metastasis.
Can machine learning predict #synbio solutions to guide cell differentiation of relevant cell types? Grantee @ScienceKyle aims to design receptors w/ custom signaling properties. 🥳 Congrats on your Hypothesis Fund award, Dr. Daniels! @StanfordMed 🙏 #HFScout @ctmurphy1 3/6
I’m excited to have support from the @Hypothesisfund to design receptors and gene circuits that control survival, proliferation, and differentiation of HSCs & T cells 🧬
Can machine learning predict #synbio solutions to guide cell differentiation of relevant cell types? Grantee @ScienceKyle aims to design receptors w/ custom signaling properties. 🥳 Congrats on your Hypothesis Fund award, Dr. Daniels! @StanfordMed 🙏 #HFScout @ctmurphy1 3/6
.@NehaPKamat on @LeonardoMorsut @CDI_UCSF work in @CellCellPress on engineered membrane receptors: cell.com/trends/biotech…
Everyone is talking about AI, but have you heard of it finding the words to kill cancer cells? This predictive model by @CDI_UCSF and @IBMResearch allows researchers to encode commands for cells to seek out and kill cells. #WorldCancerDay bit.ly/3HyXKur
@CDI_UCSF Congratulations! science.org/doi/10.1126/sc…