Chris Mesnard, Ph.D. 🧠 @CS_Mesnard

Neuroscientist interested in synaptic transmission and mitochondrial dysfunction. Former Corpsman, 3rd Battalion, 3rd Marines. Jiu Jitsu Black Belt 🥋 Omaha, NE Joined March 2013

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Michael Snyder, PhD @SnyderShot

a year ago

Our aging paper just came out. Two periods of major changes: Mid 40s and 60s. Check it out doi.org/10.1038/s43587…

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Björn Schumacher @schumacherbj

a year ago

🔥🔥🔥my 💯 paper is out, congrats 🎈🎉🍾 @Meyer_DH for this amazing story. Aging clocks tick by the noise: we can build aging clocks 🕰️ on accumulating stochastic variation! @CECAD_ @UniCologne @CGA_age @UKKoeln follow 🧵retweet & read now open access: nature.com/articles/s4358…

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Charles Brenner, PhD @CharlesMBrenner

2 years ago

good video w some caveats: though sir2 overexpression extends replicative lifespan, this only benefits 1 in 5 million yeast cells sir2 opposes lifespan in yeast & in flies--this means that the sir2 target itself doesn't make sense as something we're trying to increase in aging

Dr Brad Stanfield @BradStanfieldMD

2 years ago

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Charles Brenner, PhD @CharlesMBrenner

2 years ago

in my review on sirtuins, i documented how very weak primary research papers were amplified by an uncritical press & then codified into accepted wisdom by irreproducible primary papers & gushing review articles that went well beyond any specific result doi.org/10.1093/lifeme…

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Rava Azeredo da Silveira @Rava_daSilveira

2 years ago

Applications are open for the CNeuro2024 summer school in computational neuroscience to be held in Beijing, 8-15 July 2024. Rolling admissions starting March 1. See cneuro.net/cneuro2024 for details on program and application process.

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Jon Soucy @jrsoucy

2 years ago

Very excited to share our recent work to improve cell replacement therapies for restoring vision lost to glaucoma and other optic neuropathies! @BaranovLab @Levi_J_Todd @HMSeye @MassEyeAndEar pnas.org/doi/10.1073/pn…

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Layne Norton, PhD @BioLayne

2 years ago

The average caloric intake in the USA: 3540 kcal/day The average daily physical activity: less than 20 min But there are people out there who believe oatmeal, fruits, vegetables, & polyunsaturated fats are what is making us sick

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Dan Goodman @neuralreckoning

2 years ago

I'm happy to announce the start of a new free and open online course on neuroscience for people with a machine learning or similar background, co-developed by @MarcusGhosh. YouTube Videos and Jupyter-based exercises will be released weekly. There is a Discord for discussions.

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Ian Weissman, DO @DrIanWeissman

2 years ago

Dr. Katalin Karikó, who is sharing the Nobel Prize in medicine for her work with mRNA vaccines, says she was previously demoted by the University of Pennsylvania for her research in this area because she could not secure research funding. thehill.com/homenews/educa…

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FrezzaLab @FrezzaLab

2 years ago

congrats @AKohler_Mito @Ott_MitoLab and @langer really cool work Early fate decision for mitochondrially encoded proteins by a molecular triage: Molecular Cell cell.com/molecular-cell…

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Kirill Martemyanov Lab @KLabGPCR

2 years ago

Our systematic investigation of G protein coupling profiles of 100+ #GPCRs driven by the one and only Ikuo Masuho is out after ~10 years of work. We see many interesting patterns with the help of AI. Check it out- there is a useful reference table. doi.org/10.1016/j.celr…

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David Pla-Martín @Dpla_

2 years ago

Impressive work led by @mitodynamics. Congrats to the team! A mechanistic view of mtDNA transfer to endosomes biorxiv.org/content/10.110…

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David Pla-Martín @Dpla_

2 years ago

Have you ever wondered why mtDNA is maternally inherited? These guys found the answer! Because of TFAM!!! . Check out! nature.com/articles/s4158…

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nature @Nature

2 years ago

Psychedelics reset the brain to a youthful state in which it can easily absorb new information and form crucial connections between neurons, a study in mice suggests. go.nature.com/43I3bRL

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Elena Berezhnaya @Elena_Berezhn

2 years ago

Enhanced mitochondrial buffering prevents Ca2+ overload in naked mole‐rat brain - Cheng - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/abs/10.111…

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Natalie Gukasyan, MD @N_Gukasyan

2 years ago

Results from our multi-site study of psilocybin-assisted therapy for MDD are live today in @JAMA_current. Psilocybin had about a 12 point MADRS advantage over niacin control at day 8 that appeared durable through 6 wk follow-up. jamanetwork.com/journals/jama/… 1/

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Charles Brenner, PhD @CharlesMBrenner

2 years ago

once again, ppl are confusing a thing with a measure of a thing everyone knows that smoking accelerates aging. if it doesn't increase the score on your clock the clock is wrong

Andrew Steele @statto

2 years ago

once again, ppl are confusing a thing with a measure of a thing everyone knows that smoking accelerates aging. if it doesn't increase the score on your clock the clock is wrong

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Ruben QC @RubenQC_Lab

2 years ago

Brain mitochondria predict a mouse's stress level. doi.org/10.1038/d41586…

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FrezzaLab @FrezzaLab

2 years ago

Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired nature.com/articles/s4146…

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Dr. Dennis Eckmeier @DennisEckmeier

2 years ago

"We found receptor molecules it binds to and named them after it!" Q: Does it activate or block the receptors? A: Yes! Q: Does it only bind to these receptors? A: Nah, also lots of other receptors. Q: Do the new receptors only bind our molecules? A: Not exclusively, no.