Brett Chrest @Chrest_brett
PhD student with expertise in Mitochondrial Bioenergetics & Cancer Metabolism with @KFW_Lab┃ Focus: mSLP, Respiratory & Energy Limitations in AML🩸 Winston Salem, NC Joined July 2013-
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Successful day, love getting results that make me question the traditional 'cycle' of the TCA cycle 🤓
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Brett Chrest retweeted
And here how brain tumors exploit glucose for their growth, along with a dietary restriction of an amino acid therapy to prevent it nature.com/articles/s4158…
Caution around isolated enzyme experiments, I love this example: SUCL activity is due to succinyl-CoA production from AKGDH. Thus you can genetically down regulate AKGDH, isolate mitochondria and test maximal SUCL activity and see no difference. pmc.ncbi.nlm.nih.gov/articles/PMC36…
Brett Chrest retweeted
We present our MetaProViz #Rpackage for #metabolomics analysis & prior knowledge integration to generate mechanistic hypotheses on how metabolic changes affect metabolite classes, pathways & environment interaction 🔗biorxiv.org/content/10.110… 📦 saezlab.github.io/MetaProViz/ 🧵 Thread
Brett Chrest retweeted
Discovery happens less when you're trying to be the expert and more when you're trying to be the learner.
Brett Chrest retweeted
Congratulations to @mlvalenstein and Max Wranik and senior author Kacper Rogala on this beautiful work showing in atomic detail how amino acids activate mTORC1 via GATOR2. nature.com/articles/s4158…
Brett Chrest retweeted
A great thing about working in a lab is being involved in lab meetings and witnessing everyone's projects take shape. A single project may seem to go slow but all projects together is impressive. Caroline Bartman discussed this on the podcast: podcasts.apple.com/us/podcast/28-…
Common thought is diabetes & obesity would be worse for cancer due to increased supply of glucose for the tumor. However, using a breast tumor model, diabetic obese mice have no difference in tumor glucose metabolism compared to control diet. link.springer.com/article/10.100…
Brett Chrest retweeted
The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard
Brett Chrest retweeted
@slavov_n While whole-genome sequencing using Illumina is commonly described as such, in reality, it is closer to half genome sequencing due to limitations of sequencing (GC content) coverage, not to mention variant calling limitations that you allude to.
Brett Chrest retweeted
more negative metformin and cancer data. when will this end?
more negative metformin and cancer data. when will this end?
Brett Chrest retweeted
MOSAIC large field of view 3D single molecule localization microscopy of mitochondrial outer membranes and nuclear membranes in fixed U2OS cells.
Brett Chrest retweeted
According to DNA methylation "aging clocks", physical activity "rejuvenates" athletes immediately after the game. 𝐔𝐩𝐨𝐧 𝐫𝐞𝐬𝐭, 𝐭𝐡𝐞 𝐫𝐞𝐣𝐮𝐯𝐞𝐧𝐚𝐭𝐢𝐨𝐧 𝐝𝐢𝐬𝐚𝐩𝐩𝐞𝐚𝐫𝐬. This is inconsistent with my definition of aging. 🧵
I remember when this came out and never read it fully. Despite the title, BHB did not change overall mitochondrial function. CII is restored in critically-ill based conditions, but hard to interpret with saturating succinate + succinate from ketolysis sciencedirect.com/science/articl…
Brett Chrest retweeted
Researchers led by Ludwig @Princeton's @lynchielydia have discovered that in obese people, who are at high risk for many cancers, a diet rich in animal fats—but not plant-derived fats—suppresses antitumor immunity and promotes cancer progression. bit.ly/4fcfWu9
Brett Chrest retweeted
ONLINE NOW in @NatureCellBio: CRI DeBerardinis Lab postdoc @WalterWChen1 & international colleagues have discovered the first new human peroxin in 20 years. Read more ⬇️ cri.utsw.edu/deberardinis-l… #relentlessdiscovery
Simon Hill MSc, BSc @theproof
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Kevin C. Klatt, PhD, ... @KCKlatt
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79K Followers 2K Following Follow me to build a strong, healthy body with simple, effective home workouts. Join my free newsletter (10K+ subscribers)⬇️
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Yoni Freedhoff🎗️... @YoniFreedhoff
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Dylan Ryan @RyanLab_MBU
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MitoSense @MitoSenseInc
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Judy Butler, fan of S... @judysimpson222
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Suman Pakhira @pakhirasuman94
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Alex Rodríguez @alexsarg10
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Maria Sirenko @MariaSirenko
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seventiesteen @seventiesteen
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Mo Habibi @M_Habibi2009
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Lisa @DrugDiscoverer
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Journal of Endocrinol... @EndocrinMetab
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278 Followers 615 Following Bringing together clinical, experimental and computational scientists at the campus to drive Mitochondrial Research @UCL
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Hooman Hefzi @hhefzi
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AussieMuso @themuso2008
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Lucid Scientific, Inc... @lucidsci
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Kevin C. Klatt, PhD, ... @KCKlatt
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Thomas Dayspring @Drlipid
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David Gorski, MD, PhD @gorskon
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JT | Jerry Teixeira @jerryteixeira
79K Followers 2K Following Follow me to build a strong, healthy body with simple, effective home workouts. Join my free newsletter (10K+ subscribers)⬇️
FrezzaLab @FrezzaLab
27K Followers 3K Following We are a group of metabolism-lovers, focused on mitochondrial metabolism. Tweets are from Christian. https://t.co/EbWsJo6DnZ
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Kevin Hall @KevinH_PhD
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🐊ZK For Tre🐊 @ZKForTre
3K Followers 1K Following UF MD/PhD. PhD Neuroscience. Neurobio/Neuroimmuno/Metabolism/Stress Biology. Artist formerly known as Dr. Love/Pre-Med Guy. 🤟.
Timothy Caulfield @CaulfieldTim
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Stuart Phillips (he/h... @mackinprof
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Nick Krontiris @nick_krontiris
19K Followers 177 Following Founder, Suprastratum. Health, Fitness, Nutrition.
Yiannis (Ioannis) Ver... @YVerginadis
218 Followers 398 Following Research Assistant Professor, @Penn @PennRadOnc
Saez-Rodriguez Group @saezlab
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Eddie Rashan @EdreesRashan
955 Followers 902 Following Lipid metabolism biochemist. Postdoc @mvh_lab @KochInstitute | he/him | BlueSky: @edreesrashan.bsky.social
Silvi Rouskin @silvirouskin
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Pedro Escoll @pedro_escoll
312 Followers 382 Following Aiming to understand the metabolic side of bacterial infection #immunometabolism #legionella #salmonella #macrophages @institutpasteur
anirudh @AniRude95
480 Followers 516 Following computational postdoc @MSKCancerCenter interested in everything from metabolites to cells, physiology, behavior
Jason Bini, PhD @ScienceDrBini
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David Stroud @thestroudlab
745 Followers 503 Following Functional Genomics | Clinical Proteomics | Rare Disease You can also find us on the web and on other social platforms including https://t.co/PlOWyWHqta
Lydia Lynch @lynchielydia
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185 Followers 205 Following University of Manitoba • Pharmacology and Therapeutics • Dolinsky Lab • she/her
Chris Masterjohn @ChrisMasterjohn
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MitoSense @MitoSenseInc
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Stefan Bjelosevic @StefBPhD
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Dan Landau @landau_lab
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Alex Puissant Lab @LabPuissant
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Farese & Walther Lab @FandWLab
800 Followers 150 Following
SKI_CellBio @SKI_CellBiology
452 Followers 171 Following Twitter of the Cell Biology Program at Sloan Kettering Institute in New York. Tweets by program members (with initials) and do not represent our institutions.
Junwon.Heo @Junwon_Heo_
143 Followers 389 Following Aging_Mitochondria_Postdoc_at UWashington Medicine
Elias Tzoc-Pacheco @EliasGTP
160 Followers 644 Following Now mitochondria & metabolism @MSKCancerCenter, was biomaterials & tissue engineering @ColumbiaBME 🇬🇹
Jennifer Trowbridge @TrowbridgeLab
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Dr. Matthew CL Philli... @drmclphillips
3K Followers 62 Following Metabolic neurologist. My foremost passion is to explore metabolic strategies as potential therapies in our most difficult neurological disorders.
Kostas Votanopoulos @KVotanopoulos
273 Followers 61 Following Professor Surgical Oncology, Director Wake Forest Organoid Research Center (WFORCE) Opinions are my own.
Maria Sirenko @MariaSirenko
467 Followers 748 Following Postdoc in Aifantis and Beck Labs @nyulangone | PhD @GSKGradSchool @MSKCancerCenter @PapaemmanuilLab | population and single cell genomics in heme malignancies
Caleb Cheng @DJCalebC
567 Followers 599 Following ✝️🇹🇼🇺🇸MD/PhD candidate studying pancreatic cancer in @ArulChinnaiyan and @Lyssiotislab at @UmichMedSchool
Ramon Sun @RCSunlab
1K Followers 1K Following Director, UF-CASBR | On a mission to cure dementia and cancer in 5 years.
Mo Habibi @M_Habibi2009
149 Followers 662 Following Postdoctoral Research Associate #metabolism #liver_fibrosis #MASLD #MASH Washington University School of Medicine @bnfinck lab
Katrina Paras @kiparas21
47 Followers 45 Following PhD student @WeillCornellGS and @MSKCancerCenter in the Finley Lab | @UCLA alum
Milan Savani @milan95
319 Followers 475 Following MD student @UTSWnews. PhD from the McBrayer lab @CRI_UTSW. @PennSAS & @Wharton grad. Views my own; RT ≠ endorsements. He/him.
Kivanc Birsoy @KivancBirsoy
4K Followers 392 Following Associate Professor at the Rockefeller University
David Pla-Martín @Dpla_
2K Followers 732 Following Professor @hhu_de Mitochondrial Biology 🧬 | Institute of Biochemistry and Molecular Biology I | mitochondria, mtDNA and mitophagy 🇪🇸🇩🇪https://t.co/JDKjL8tUSr
Elizabeth Coffee, MD @ECoffeeMD
112 Followers 188 Following Biomedical Engineer turned Neuro-Oncologist researching metabolic imaging techniques in CNS tumors MSKCC. Tweets are my own.
Nirosha J. Murugan @msahsorin
4K Followers 771 Following Tier II Canada Research Chair in Tissue Biophysics & Assistant Professor. Leveraging biophysical & quantum signals to redefine health.
UCL_CfMR @UCL_CfMR
278 Followers 615 Following Bringing together clinical, experimental and computational scientists at the campus to drive Mitochondrial Research @UCL
Brandy Zadrozny @BrandyZadrozny
119K Followers 4K Following Senior Reporter @MSNBC SEND ME TIPS: Reach out securely on a non-work device: Signal brandyzadrozny.53 Send nice letters: [email protected]
Professor Richard Sco... @ProfRAScolyer
22K Followers 200 Following Surg Pathologist RPAH. Prof @Sydney_Uni. 2024 Jt Australian of Year. Editor @WHO Skin (4th ed). @AJCCancer VC Mel Expert Panel. All posts/comments are personal.
Ziad Bakouny, MD, MSc @ZiadBakouny
4K Followers 2K Following PGY-5 Heme/Onc @MSK_DeptOfMed | via @USJLiban @DanaFarber @BrighamMedRes | @ASCO #IMG CoP & #JCOCCI Assoc Editor | Opinions my own | FCOI: https://t.co/dYsEwGGqP1
Slavov Laboratory @slavovLab
3K Followers 125 Following We seek principles in the coordination among protein synthesis, metabolism, cell growth and differentiation PI: @slavov_n Videos: https://t.co/tfkuZB7tgw
Roger J Davis @RogerJDavis1
1K Followers 932 Following Biomedical scientist. Professor & Chair, Molecular Medicine, UMASS Chan Medical School
Scott Millman, MD PhD @ScottMillmanMD
82 Followers 90 Following Medical Oncologist and Leukemia Researcher at MSKCC. Tweets are my own.
Thilo J. Zander @ThiloZander
1K Followers 853 Following MD. Medical Oncologist. Focused on innovative Lymphoma & Myeloma care. Opinions solely personal views.
Robert Pozner MD Phd ... @thunder7125111
5K Followers 259 Following Medical Director research @harvard | Professor of Medicine & Surgery at @HarvardMed | @BrighamWomens @Harvard @MIT alum| Opinions are my own| #MedEd #SurgEd
Marco Sciacovelli @MSciacovelliLab
334 Followers 943 Following Tenure Track Fellow (Group Leader) at @LivUniISMIB. Studying cancer metabolism, mitochondria, metabolite signalling. Views are my own.
Itai Yanai @ItaiYanai
32K Followers 2K Following Professor at the NYU School of Medicine. Co-host of the 'Night Science Podcast' @nightsciencepod and Co-founder of the Night Science Institute https://t.co/lede3rBmXU
Richard Sever @cshperspectives
20K Followers 1K Following Chief Science and Strategy Officer, openRxiv. bioRxiv & medRxiv Co-Founder
Dr. Catharine Young @DrCatharineY
30K Followers 20K Following Scientist || Immigrant || Senior Fellow @HarvardChanSPH || Fmr: White House #CancerMoonshot, @CornellBME, @TEDFellow || 🇿🇦 + 🇺🇸
Kamran Mirza MD PhD -... @KMirza
27K Followers 10K Following Godfrey D. Stobbe Professor of #Pathology | Assistant Chair for Education | @UMichPath @UMichMedicine 〽️ | #Hemepath | Assoc. Editor ASH Image Bank | Views Mine
Katherine Ansley, MD @KatherineAnsley
306 Followers 369 Following Med Onc specializing in breast cancer at Atrium Health Wake Forest Baptist. The views here are my own and do not necessarily reflect those of Advocate Health
van den Brink Lab @vandenBrinkLab
828 Followers 603 Following Updates from the van den Brink Lab 🧪 Department of the Beckman Research Institute at City of Hope. All tweets and opinions are our own.
ASH @ASH_hematology
71K Followers 2K Following The American Society of Hematology (ASH) is the world's largest professional society concerned with the causes and treatments of blood disorders.Trends for United States
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