Cyrus Ghajar @GhajarLab
The mission of our lab is to develop metastasis prevention strategies by understanding the biology of disseminated tumor cells and their microenvironments. research.fhcrc.org/ghajar/en.html Seattle, WA Joined October 2012-
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Cyrus Ghajar retweeted
Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday nature.com/articles/nmeth…
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Cyrus Ghajar retweeted
We are putting together an exciting program with fresh perspectives and new biology!! Come join us next year in Portugal! @DelgoffeLab @Joshilabyale 🪐⏳
We are putting together an exciting program with fresh perspectives and new biology!! Come join us next year in Portugal! @DelgoffeLab @Joshilabyale 🪐⏳
Cyrus Ghajar retweeted
Over the moon that my student's article won the Octavio Frias prize in oncology research. Thanks Ana Maria Rodrigues for the amazing work and all co-authors that made this possible! youtube.com/watch?v=O_9r38… nature.com/articles/s4138…
Cyrus Ghajar retweeted
I've developed CellBioStats, an app for visualization and statistical analysis of cell and molecular biology data . It helps to avoid common pitfalls like pseudoreplication and automatically checks the appropriate stats for paired or unpaired data. github.com/brunicardoso/C…
Cyrus Ghajar retweeted
Excited to share our review on metabolic adaptations in brain metastasis in @NatureRevCancer!! 👉rdcu.be/exHzY A pleasure to co-write with Pravat @CMTLab_IISERBPR and appreciate the support Daniela @DaniS2911 @utswcancer @utswcancerBio @UTSW_Pathology @UTSWMedCenter
Cyrus Ghajar retweeted
T cells do the heavy lifting when it comes to the anti-tumor action of checkpoint immunotherapy. But do antibodies play a role too? That’s the question @Yile_Dai looked to answer in his thesis work, out today in @Nature! 🧵below nature.com/articles/s4158…
Cyrus Ghajar retweeted
Spread the word: The European Center for Angioscience @UniHeidelberg continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @Nature: nature.com/naturecareers/…
Cyrus Ghajar retweeted
Super excited to share our newest piece out today @NatureRevCancer linking age-induced metabolic reprogramming to cancer development. nature.com/articles/s4156…
Way to go @ShiLi15531547 !!!
Cyrus Ghajar retweeted
Excited to share our new study on how resistance to AKT inhibition is linked to lineage differences within breast cancer 👇🏽biorxiv.org/content/10.110… and also surprisingly/worryingly good AI generated podcast 🎧notebooklm.google.com/notebook/28ebc…
Cyrus Ghajar retweeted
New paper out! We show amino acid restriction triggers genome-wide H4K20me1 loss and MYC activation—priming cells for rapid protein synthesis upon refeeding. A chromatin-based strategy for surviving nutrient stress with implications for MYC-driven cancers. cancerandmetabolism.biomedcentral.com/articles/10.11…
Cyrus Ghajar retweeted
Between alarms and sheltering, I learned last night that my postdoc mentor, Professor Atul Butte @atulbutte, has passed away, and he is only 55 years old. This is devastating news 💔. Atul was a giant in so many ways. He was a visionary leader in translational bioinformatics…
Patrick Paddison and friends lighting it up!
Patrick Paddison and friends lighting it up!
Beautiful and compelling new work from the Perera Lab:
Beautiful and compelling new work from the Perera Lab:
Such an honor to present Senator @PattyMurray with an award on behalf of @NBCCStopBC for her unwavering support of NBCC’s legislative priorities, especially the DoD Breast Cancer Research Program. We’re very lucky to call her our Senator.
My favorite Berkeley Alum Dan the MF Man Rubinoff discussing one of his more amazing discoveries:
My favorite Berkeley Alum Dan the MF Man Rubinoff discussing one of his more amazing discoveries:
Cyrus Ghajar retweeted
#AACR25 come check out SY20 Wednesday at 10:15am to discuss Lymph Nodes and Lymphoid Structures in Cancer with me, @BcellBruno and @ZivShulman !!
Cyrus Ghajar retweeted
What factors enable CAR-Ts to respond to checkpoint blockade, and can they be engineered to be more sensitive to enhancement? We explore this question in our lab’s first pre-print, led by MSTP student @AndrewAJSnyder1 with great collaborations with @EvNewell1 and @ScottFurlan. 1/
What factors enable CAR-Ts to respond to checkpoint blockade, and can they be engineered to be more sensitive to enhancement? We explore this question in our lab’s first pre-print, led by MSTP student @AndrewAJSnyder1 with great collaborations with @EvNewell1 and @ScottFurlan. 1/
Cyrus Ghajar retweeted
1/ Excited to share CellFlow, a new approach for complex perturbation modeling in single-cell genomics based on flow matching. From cytokine screens to cell fate and organoid engineering, we show CellFlow’s broad power across many diverse tasks. 👉 Paper: biorxiv.org/content/10.110…
Cyrus Ghajar retweeted
Interested in the mysteries surrounding metastasis evolution? This perspective in @NatureRevCancer is my best attempt at proposing a framework that could help advance our thinking about the topic. Well. At least it helped advance my own thinking. 😅 nature.com/articles/s4156…
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