Aaron Ring @aaronmring
Associate Professor at @FredHutch Studying #cytokines, (auto)antibodies, and #cancerimmunotherapy Founder: @SimchaTx, @Seranova, Stipple Bio, and @AriaxBio Seattle, WA Joined December 2017-
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Aaron Ring retweeted
Go outside w a team Get exercise Give back A protocol for happiness :-) Thanks @ldtimmerman for bringing our community together throughout the year in such special ways Mount Katahdin, here we come! We're raising funds this time to support @DamonRunyon
Go outside w a team Get exercise Give back A protocol for happiness :-) Thanks @ldtimmerman for bringing our community together throughout the year in such special ways Mount Katahdin, here we come! We're raising funds this time to support @DamonRunyon
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FreeBindCraft has been a fun evening hobby project. Can PyRosetta be replaced in BindCraft with open-source alternatives? Answer: so far it seems to work great and runs considerably faster. Hopefully this can tide us over until @MartinPacesa releases BindCraft2. PRs welcome!
FreeBindCraft has been a fun evening hobby project. Can PyRosetta be replaced in BindCraft with open-source alternatives? Answer: so far it seems to work great and runs considerably faster. Hopefully this can tide us over until @MartinPacesa releases BindCraft2. PRs welcome!
Major congrats to @MartinPacesa and the team. Let's get 1000+ citations for BindCraft now! 😎
Major congrats to @MartinPacesa and the team. Let's get 1000+ citations for BindCraft now! 😎
I'm now the proud owner of a bespoke, handcrafted 96 well magnetic separator designed by my Twitter BFF @AdrianoAguzzi. Thanks a million!!!
Aaron Ring retweeted
BindCraft isn't just for miniproteins. A new preprint validates 47-67% success rates for BindCraft-derived peptides with nM affinities. Our tutorial with @MartinPacesa covers this work and walks through our new dedicated peptide interface. Read it here: ariax.bio/resources/bind…
Aaron Ring retweeted
CAR-T cells against solid tumors. Listen to @sabahoney on The Long Run. timmermanreport.com/2025/08/car-t-…
Aaron Ring retweeted
Could the same proteins that drive autoimmune disease help fight cancer? In @Nature, Emerging Leader Award winner @aaronmring of @fredhutch shows that some autoantibodies are linked to better outcomes for patients receiving checkpoint inhibitor therapies. fredhutch.org/en/news/releas…
Aaron Ring retweeted
Chinese Hamster Ovary, or CHO cells, make roughly 70 percent of all F.D.A. approved biologics sold on the market. This includes bestsellers like Humira®, used to treat Crohn’s and rheumatoid arthritis, and Keytruda®, a cancer therapy. Despite their ubiquity in the pharmaceutical…
Martin is a breakout star in the AI-powered protein design space. He led the effort to create BindCraft and he's just getting started. I can't think of a better lab to do a post-doc or contribute as professional research staff if you want to get into this space.
Martin is a breakout star in the AI-powered protein design space. He led the effort to create BindCraft and he's just getting started. I can't think of a better lab to do a post-doc or contribute as professional research staff if you want to get into this space.
Aaron Ring retweeted
This month, the Big Ten Cancer Research Consortium highlights our member institution @fredhutch Cancer Center and Lawrence Fong, MD, who serves as scientific director of the Immunotherapy Integrated Research Center at Fred Hutch. Read more: bigtencrc.org/member-feature…
Aaron Ring retweeted
Clone tracing T cell responses in cancer (using TCR-seq methods) has been incredibly valuable for understanding immunotherapy response and opportunities. A holy grail for us has been thinking about to achieve this for innate immune responses in human cancer - with high accuracy…
Clone tracing T cell responses in cancer (using TCR-seq methods) has been incredibly valuable for understanding immunotherapy response and opportunities. A holy grail for us has been thinking about to achieve this for innate immune responses in human cancer - with high accuracy…
Aaron Ring retweeted
Excellen nanomolar peptide binder design success rates with BindCraft!
Excellen nanomolar peptide binder design success rates with BindCraft!
Aaron Ring retweeted
I am super excited to announce that I will be starting my lab at the Department of Pharmacology of the University of Zurich in Switzerland next year!
Aaron Ring retweeted
BREAKING: We uncovered a potent immune alliance that could change how we treat solid tumors. Published in @Cancer_Cell , we show that Th17 cells *must* work with B cells to eliminate tumors—and keep it from coming back. 📄 cell.com/cancer-cell/fu… 🧵1/12👇Let’s walk through it:
Aaron Ring retweeted
The Weill Cancer Hub is fostering groundbreaking @UCSF–@Stanford collaborations to develop transformative cancer therapies. I’m grateful to co-lead one of the selected teams with @mfgrp to advance next-generation in vivo CAR T cell therapy!
Aaron Ring retweeted
Excited to share this new work from our lab, led by an exceptional graduate student, Tornike Mamuladze (@tornikemamu), on the role of meningeal mast cells in regulation of brain/dura access points, with implications to CSF flow dynamics and meningitis || authors.elsevier.com/sd/article/S00…
Aaron Ring retweeted
Published today our new LAG-3 paper @CellCellPress. My group #JasperDu #JiaYou and collaborators revealed a key role of TCR proximity in LAG-3’s inhibitory function and developed LAG-3/TCR BiTS to effectively inhibit LAG-3+ T cells. dlvr.it/TLhkv7
Aaron Ring retweeted
A landmark study published in @Nature by @aaronmring et al. has revealed that autoantibodies — immune proteins traditionally associated with autoimmune disease — may profoundly influence how cancer patients respond to immunotherapy. bit.ly/4o4HANS
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