Madhav Thambisetty @MadhavThambiset
Neurologist. Neuroscientist. Discovering cures for Alzheimer's disease. Tweets are my personal opinions. linkedin.com/in/madhav-tham… Baltimore, MD Joined September 2013-
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Misleading to claim #donanemab or any amyloid lowering Rx will allow an #Alzheimer’s patient to continue to drive independently. Inserting the claim immediately outside a respected KOL’s quote also risks wrongly attributing this to them. Not a good look @ProfRobHoward @pash22
Misleading to claim #donanemab or any amyloid lowering Rx will allow an #Alzheimer’s patient to continue to drive independently. Inserting the claim immediately outside a respected KOL’s quote also risks wrongly attributing this to them. Not a good look @ProfRobHoward @pash22 https://t.co/gxodytrnSZ
cricket.one/cricket-news/p… What could possibly go wrong when a supposedly bankrupt cricket star is bailed out by the richest family in the country to abruptly switch sides in the most lucrative T20 league in the world? 🤷♂️
We're on! April 19 - register now! mcisymposium.org/program
Is amyloid=Alzheimers? YES: @alzassociation Does lowering brain amyloid predict benefit? YES: @US_FDA Is lowering brain amyloid safe & effective? YES: drug makers Should we cover amyloid abs? YES: CMS Should we prescribe them? YES: MDs #Consensus #no-debate @AlbertoEspay
Only 1 in 4 respondents to a recent @McKnightBrain1 survey have talked to their doctor about brain health. Talking to your doctor is a great way to be proactive about maintaining your brain health. Learn more & get tips to start the conversation here: McKnightBrain.org/BrainWorks.
Fewer Than 1/2 of Accelerated Approval Rx Showed Clinical Benefit in Confirmatory Trials After 5 Years tinyurl.com/ydfznwx3 @dcweisman @mroliverbarnes @pash22 @ProfRobHoward A sobering and timely analysis suggesting that cancer-envy in dementia drug approvals may be misplaced
It’s a grim business when even getting your manuscript past the editor’s desk and into reviewer’s hands seems like a major victory 🤷♂️
A breathtaking story indeed. @jtemperton 🙏 thanks for writing it. Inspiring, sobering, uplifting and sad in equal measure. @Jasonmmast did you see this?
A breathtaking story indeed. @jtemperton 🙏 thanks for writing it. Inspiring, sobering, uplifting and sad in equal measure. @Jasonmmast did you see this?
#DYK simple lifestyle changes can help maintain brain health with age? Only 32% of @McKnightBrain1 survey respondents believe there are steps they can take to protect their brain health, but eating a healthy diet, exercising & getting enough sleep can benefit the brain & body.
We're excited to be kicking off Cognitive Aging Summit IV in partnership with @FNIH_Org & @NIHAging. Scientific presentations on the social, biologic & genetic factors that drive healthy aging are underway. If you aren't here, join us virtually at: fnih.org/our-programs/c….
The fourth Cognitive Aging Summit is underway! It’s not too late to join us via livestream to learn about the individual factors that affect brain health as we age: lnkd.in/eJbBhZhV @McKnightBrain1 @NIHAging #CASIV #aging #healthyaging #fnih
Use of Lecanemab for Patients With Cardiovascular Disease jamanetwork.com/journals/jama/…
A friendly, respectful & collegial debate on the pros & cons of amyloid-targeting antibodies at the #ASENT meeting in Bethesda @ASENT_Org with @dcweisman @AlbertoEspay & John Dickson from MGH. Thanks for participating!
This situation is surreal. WTF @Harvard and @CDCgov? “Science cannot survive in a society that does not value truth and strive to discover it. The scientific community will gradually lose public support and slowly disintegrate in such a culture.”
Safe to say this is the most head spinning, vertigo-inducing day for neurodegenerative diseases that I can recall @ProfRobHoward @pash22 @AlbertoEspay @schrag_matthew @TharickAPascoal
Effects of unblinding may explain a significant share of the observed treatment effects for all amyloid-targeting Rx @SFAckley @ProfRobHoward @kathy_y_liu @LonSchneiderMD @MariaGlymour @nvillain_alz @schrag_matthew
Effects of unblinding may explain a significant share of the observed treatment effects for all amyloid-targeting Rx @SFAckley @ProfRobHoward @kathy_y_liu @LonSchneiderMD @MariaGlymour @nvillain_alz @schrag_matthew https://t.co/0dCt9t55BI
Robert Howard @ProfRobHoward
15K Followers 2K Following UCL old age psychiatrist | Improving dementia and mental health treatment | Independent trials | Layla | Talk to me about academic careers
Matthew Schrag @schrag_matthew
3K Followers 314 Following Neurologist focused on Alzheimer's disease, cerebral amyloid angiopathy and stroke. Principal investigator for SchragLab.
Alberto J Espay @AlbertoEspay
8K Followers 630 Following #Neurology professor @uofcincy. Advocate of precision medicine in #Parkinsons & #Alzheimers. Cofounder of Regain to correct proteinopenia. Author #BrainFables.
Andreas Charidimou MD.. @a_charidimou
18K Followers 5K Following Neurologist | Asst. Prof @bmcneurology @BUMedicine | Stroke,🩸🧠 Cerebral Amyloid Angiopathy, Dementia, Brain Small Vessel Disease
Jason Karlawish @jasonkarlawish
4K Followers 578 Following Physician/writer @Penn, codirector @Penn_Memory Center. Beginning Feb 1, '24 I'm on a writing break and so quiet here. Please visit my website to message me.
Karl Herrup @KarlHerrup
3K Followers 2K Following Solving all of human disease in alphabetical order Alzheimer's, ataxia-telangiectasia, autism. Professional iconoclast. International outlook. Politics separate
Reshma Ramachandran @reshmagar
3K Followers 3K Following @YaleMed Assistant Prof, @Yale_CRRIT Co-Director, @UAEM NA Board Prez, @Drsforamerica FDA Task Force Chair #access2meds #patientsbeforeprofits #openaccess
Charles Piller @cpiller
5K Followers 625 Following Investigative reporter @sciencemagazine. Before: investigations for @statnews @sacbee_news @latimes. [email protected] - Signal 510.469.7984 - open DMs.
Nicolas Villain @nvillain_alz
976 Followers 863 Following Neurologue Chercheur - Neurologist Researcher #Alzheimer #Dementia #Neurodegeneration @FaculteSanteSU @Sorbonne_Univ_ @HopPitieSalpe @APHP @InstitutCerveau
RMR @MedinaRiojaMD
9K Followers 2K Following Neurologist. 🥼 Dementia and Neurodegenerative Disorders / 🎵, 📚, Med Edu and 🧠. Social Media Co-Editor for @AMEVASC1/@ArchNeurocien . #INNN #MédicaSur🤓🇲🇽
Adam Feuerstein ✡�.. @adamfeuerstein
114K Followers 750 Following Reporter @statnews. The Harry Kane of biotech. Dog ❤️er. Polk Award winner. #COYS. Said one analyst: The likes of Adam Feuerstein attack viciously.
Nicholas Ashton @NicholasAshton
2K Followers 807 Following Neuroscientist in Dementia / University of Gothenburg 🇸🇪 / King's College London 🇬🇧 / Centre for Age-Related Medicine 🇳🇴
Lon S. Schneider, MD @LonSchneiderMD
2K Followers 472 Following University of Southern California, Alzheimer Disease Research Center
Timothy Daly, PhD @PhilAlz
1K Followers 1K Following Alzheimer's ethics poetry @FLACSOargentina @Sorbonne_Univ_ @acversailles speaks 🇬🇧 🇫🇷 🇪🇸 🇵🇹 learning 🇦🇩 🇮🇹 🏴 🇩🇪
Liana Apostolova, MD,.. @ApostolovaLiana
2K Followers 649 Following Cognitive neurologist and Alzheimer's disease researcher, Indiana University Distinguished Professor, Principal Investigator of LEADS, Editor-In-Chief DADM
Dave Weisman @dcweisman
2K Followers 2K Following Private practice neurologist and trialist. The line separating smart and dumb passes right through every human brain.
Nick Corriveau-Lecava.. @CorriveauNick
5K Followers 3K Following Neuropsychologist studying the degenerating mind at @MayoClinic @NaipMayo | Assistant Prof @MayoClinicNeuro & @MayoPsych
Ian Kremer @LEAD_Coalition
67K Followers 47K Following Working to end #Alzheimers/#dementia. @WUSTL @UMichLaw https://t.co/GJkJVm4vF2 https://t.co/dd0eOpRj6V https://t.co/1ARWoHKsQu
Maria Teresa Ferretti @MaTeFerretti
3K Followers 4K Following Neuroscientist, brain health advocate, editor, cancer survivor, TED-x speaker, author. Anything related to the brain interests me–but #Alzheimer is my passion
David Oliver @mancunianmedic
72K Followers 27K Following NHS Dr 35 y. Covid wards++ Gov, policy, academic, officer roles. Byline: @BMJ_latest. Columns: health press, papers. @mjauk. Manc-in-South. MCFC. Craic. Schlock
Heather Jobe @HeatherJob96127
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Dark Revival Film @DarkRevivalFilm
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Ivy Ventrone @ventr_i
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Wenjie Hou @DanTouHaHa
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Dr Lia ‘biopsychoso.. @LJ_Ali1
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Jerry Najdowski @JerryNajdowski
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Gully Foyle @bluejaunt100
434 Followers 368 Following RTFM for drug development and the regs. No positions, just comments prn.
Nicole Grady @NicoleGrady17
207 Followers 568 Following Chicagoan, healthcare PR professional. Loves food, wine, politics, travel and Chicago sports. All opinions are my own.
Aurora @nonomiyara83410
0 Followers 106 Following
🇺🇸Paul Mampilly @MapillyGuru
116 Followers 1K Following Ex hedge fund mgr, 30 yr Wall St Pro. Now @atgdigital analyst. #Bitcoin | $TSLA| #crypto | innovation & macro. Only opinions no investment advice.
Kimbra Ghera @GheraKimbr26263
75 Followers 5K Following
Walt Bogdanich @waltbogdanich
3K Followers 476 Following Investigative reporter & co-author of New York Times best seller, When McKinsey Comes to Town, 3x Pulitzer winner. Fan of all things Cleveland.
Forgotten History @forgottenFacts0
36 Followers 1K Following Here to aware you of the sidelined and forgotten historical facts.
Reaslab @reas_lab
32 Followers 94 Following The Reas lab @UCSanDiego uses #neuroimaging to study #Alzheimers disease and brain #aging. PI @etreas
Scott Arroyos @ArroyosSc
51 Followers 5K Following
Nayeli Dershem @ders_naye
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vcj0zfd532q @zb8f9udoz
14 Followers 1K Following We first transfer USDT to you TRC20, you return 90% to BEP20, you get 10% , 2K per day Our co hv a large amt of USDT need to from TRC20 convert to BEP20 network
Matilda Mientka @MientMatild
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Neurogeek @mindfulneurons
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Ardath Coriell @ArdathC52503
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Being Patient @Being_Patient_
2K Followers 2K Following Editorially independent source for news, science & human stories from #brainhealth experts, scientists, #caregivers & people living with #Alzheimers & #dementia
PJ179 @PJ17862
324 Followers 1K Following #WearARespirator #covidisairborne #eldercare #covidisntover #maskup #uncommitted #immunocompromised #autoimmune #rheum #highriskcovid19 #n95 #ceasefirenow #mask
Anantha Korrapati @AKorrapati18
53 Followers 328 Following NIH IRTA Fellow | Neuroscience | Genetics | Health Policy | Environmental Health | Incoming Student at UAB Heersink School of Medicine 🐉
Kelly Whitehead @cjb204yien7
0 Followers 194 Following Startups | Fintech | E-commerce | Operator and investor
Aki Yosh. @aki_tokyo11
257 Followers 417 Following PhD candidate, Arch. design for Dementia |Master's alum 🇺🇸 @uchicago & UTokyo Grad School| 🌎2024-25 @alzassociation @ISTAART Ambassador🎖Follow for updates💗
André Millet ⚡ @andremillet
30 Followers 153 Following Médico pela faculdade de Medicina Souza Marques, Pós-Graduado em Neurologia pela IPEMED/RJ.
Linnea Seilhamer @SeilhaLinn
63 Followers 5K Following
SAVI Dual TMS Migrain.. @SaviDual
322 Followers 1K Following Treat & Prevent #Migraine. Portable, noninvasive therapy using science of Central Nueromodulation & Transcranial Magnetic Stimulation (TMS) #Veterans VA Benefit
Ahmed Negida, MD PhD .. @NegidaMD
9K Followers 3K Following Postdoctoral Scholar PGY-6 @VCUHealth | Formerly @HarvardMed | Global Lead @Global_Nsurg | #Neurology #Neurosurgery | Instructor @NegidaAcademy
Ameerah Eggink @AmeerahEgg41754
70 Followers 5K Following
Shyla Arguelles @ArguellesS18632
104 Followers 5K Following
Adrian Maronge @adri_maron
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Asha Hudkins @HudkiAs
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Eryn Mccutcheon @mccutch_e
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Professor Benedict D .. @BenedictNeuro
3K Followers 4K Following Neurologist. Professor. Director of @InfectNeuroLab- working on CNS Infections. MGH/HMS. Vice Chair @Encephalitis. Educator.
Abi Prukop @pruko_a
33 Followers 5K Following
Amit Singh @amitveer
129 Followers 649 Following Immunologist, Science and Nature lover. Now getting interested in science communication too.
Madalene Tupacyupanqu.. @MadaleneTu33264
81 Followers 5K Following
Luella Stanislaw @LuellaStan7815
82 Followers 5K Following
Sutton Schwerd @sutto_schw
87 Followers 5K Following
Artemesia Mendelsohn @ArtemesiaM78196
61 Followers 5K Following
The Whole INTJs Catal.. @INTJs2024
585 Followers 5K Following “🌌 Exploring the cosmos within | Mastermind musings | #INTJInsights” https://t.co/FBhvdoE9GT
Lily-may Delaplane @DelaplaM
37 Followers 5K Following
Robert Howard @ProfRobHoward
15K Followers 2K Following UCL old age psychiatrist | Improving dementia and mental health treatment | Independent trials | Layla | Talk to me about academic careers
Matthew Schrag @schrag_matthew
3K Followers 314 Following Neurologist focused on Alzheimer's disease, cerebral amyloid angiopathy and stroke. Principal investigator for SchragLab.
Alberto J Espay @AlbertoEspay
8K Followers 630 Following #Neurology professor @uofcincy. Advocate of precision medicine in #Parkinsons & #Alzheimers. Cofounder of Regain to correct proteinopenia. Author #BrainFables.
Andreas Charidimou MD.. @a_charidimou
18K Followers 5K Following Neurologist | Asst. Prof @bmcneurology @BUMedicine | Stroke,🩸🧠 Cerebral Amyloid Angiopathy, Dementia, Brain Small Vessel Disease
Alzforum @alzforum
11K Followers 340 Following A news and information resource website helping scientists advance AD research since 1996. Alzforum doesn’t endorse any specific product or scientific approach.
Jason Karlawish @jasonkarlawish
4K Followers 578 Following Physician/writer @Penn, codirector @Penn_Memory Center. Beginning Feb 1, '24 I'm on a writing break and so quiet here. Please visit my website to message me.
Michael Okun @MichaelOkun
34K Followers 861 Following National Medical Advisor @parkinsondotorg Author 14 books https://t.co/EJCwDpEIw8 blog Professor @UF @fixelinstitute Associate Editor @JAMANeuro @DBSThinkTank
Eric Topol @EricTopol
694K Followers 589 Following physician-scientist, author, editor. Ground Truths: https://t.co/YhatcBT0hA
Karl Herrup @KarlHerrup
3K Followers 2K Following Solving all of human disease in alphabetical order Alzheimer's, ataxia-telangiectasia, autism. Professional iconoclast. International outlook. Politics separate
Vinay Prasad MD MPH @VPrasadMDMPH
287K Followers 4K Following Prof @ucsf, Physician-Scientist, IG @vprasadmdmph @vkprasadlab @plenary_session, YouTube, #vpzd podcast & @Sensible__Med; Views mine
Reshma Ramachandran @reshmagar
3K Followers 3K Following @YaleMed Assistant Prof, @Yale_CRRIT Co-Director, @UAEM NA Board Prez, @Drsforamerica FDA Task Force Chair #access2meds #patientsbeforeprofits #openaccess
Brain @Brain1878
65K Followers 172 Following Brain: A Journal of Neurology. Publishing leading studies in neurological science since 1878.
Charles Piller @cpiller
5K Followers 625 Following Investigative reporter @sciencemagazine. Before: investigations for @statnews @sacbee_news @latimes. [email protected] - Signal 510.469.7984 - open DMs.
Nicolas Villain @nvillain_alz
976 Followers 863 Following Neurologue Chercheur - Neurologist Researcher #Alzheimer #Dementia #Neurodegeneration @FaculteSanteSU @Sorbonne_Univ_ @HopPitieSalpe @APHP @InstitutCerveau
Adam Feuerstein ✡�.. @adamfeuerstein
114K Followers 750 Following Reporter @statnews. The Harry Kane of biotech. Dog ❤️er. Polk Award winner. #COYS. Said one analyst: The likes of Adam Feuerstein attack viciously.
Nicholas Ashton @NicholasAshton
2K Followers 807 Following Neuroscientist in Dementia / University of Gothenburg 🇸🇪 / King's College London 🇬🇧 / Centre for Age-Related Medicine 🇳🇴
Lon S. Schneider, MD @LonSchneiderMD
2K Followers 472 Following University of Southern California, Alzheimer Disease Research Center
Liana Apostolova, MD,.. @ApostolovaLiana
2K Followers 649 Following Cognitive neurologist and Alzheimer's disease researcher, Indiana University Distinguished Professor, Principal Investigator of LEADS, Editor-In-Chief DADM
Brad Loncar @bradloncar
69K Followers 365 Following #Biotech, Founder of @BiotechTVHQ, KC native, @univmiami hurricane.🧬🙌
Neurology Journal @GreenJournal
92K Followers 1K Following Neurology is the most widely read and highly cited peer-reviewed neurology journal. It is the medical journal for the American Academy of Neurology.
Katherine Eban @KatherineEban
22K Followers 2K Following Award-winning investigative journo. Special Correspondent, @VanityFair. NYT bestselling author. @CarnegieCorp fellow. Partial to animals. DM 4 Signal.
Walt Bogdanich @waltbogdanich
3K Followers 476 Following Investigative reporter & co-author of New York Times best seller, When McKinsey Comes to Town, 3x Pulitzer winner. Fan of all things Cleveland.
Ian Sample @iansample
46K Followers 1K Following Guardian science editor and podcast presenter | PhD | Massive, shortlisted Royal Society Science Book Prize | Sony Award | Leaks to [email protected]
Sharon Brangman @SharonBrangman
753 Followers 715 Following geriatrician; ethnogeriatrics; Alzheimer’s disease; social justice; SUNY Upstate Chair of Geriatrics; my opinions are mine and happy to share them!@AKA1908
Go Northeast @GoNorthEastIN
42K Followers 139 Following Exploring the uncharted beauty of Northeast India 🌄 follow us on a journey to the Seven Sisters & beyond! 🛤️" contact 7876136946 for North East travel plan
David Fajgenbaum, MD @DavidFajgenbaum
11K Followers 3K Following @Penn physician-scientist-patient who 'cured thyself' | Advancing @CureCastleman + @EveryCure | National Bestseller #ChasingMyCure https://t.co/26OS13etrF
Denis Wirtz @deniswirtz
39K Followers 8K Following VP for Research @JohnsHopkins, T.H. Smoot Professor @HopkinsEngineer & @HopkinsMedicine, Co-founder @INBT_JHU, Lab: https://t.co/9OtmgB6InU Tweets are my own.
Cheshire @Thatsregrettab1
2K Followers 346 Following 👉 Not a scientist, just a nuisance 👈 [email protected]
Seb Walsh @seb_walsh
835 Followers 909 Following Public Heath Doctor and NIHR Doctoral Fellow researching population approaches to dementia risk reduction @CamPubHealth. Views own, retweets not endorsements.
Jen Bizon @JenBizon
1K Followers 2K Following Neuroscientist (half of team Bizon-Setlow), professor and chair of UF neuroscience, mom, daughter, sister, tweets my own.
Casey Albin, MD @caseyalbin
19K Followers 1K Following Neurointensivist @EmoryNeuroCrit | @ContinuumAAN media AE | Passionate about #FOAMncc & acute neurology
Carl Elliott @FearLoathingBTX
6K Followers 6K Following MD PhD @UMNphilosophy, author of The Occasional Human Sacrifice, in press @wwnorton. Words in @TheAtlantic @NewYorker @nytimes @nybooks @DavidsonCollege '83
ed silverman @edsilverman
6K Followers 155 Following Pharmalot columnist and senior writer at @STATnews.. former WSJer.. proud dad; likes music, dogs and taking naps
Tweets from Zach Wein.. @zachweinberg
59K Followers 350 Following I do healthcare & tech stuff. Founder of https://t.co/uJTXjZVNJt, Flatiron Health (acq @Roche~$2b) & Invite Media (acq @Google~$81m). Invest @ https://t.co/2D00yW2Be4
American Neurological.. @TheNewANA1
11K Followers 2K Following ANA is a professional society of academic neurologists and neuroscientists. Interested in becoming a member? Visit https://t.co/PT9HNOkmsG to learn more!
Rita Redberg @RFRedberg
6K Followers 393 Following UCSF cardiologist. NYC born and bred. Avid cyclist. Working to make needed health care accessible and affordable for all.
Alexander Trevelyan @ClicksAndHisses
506 Followers 346 Following Biotech Software Dev 🧬 | Physics PhD ⚛️| 🌻 No longer supporting this whole "X" trainwreck.
Vinod Khosla @vkhosla
632K Followers 575 Following entrepreneurship zealot, grounded technology possibilist, believer in the power of ideas, passionate about sustainability & impact
Meduza in English @meduza_en
115K Followers 7 Following Breaking news in Russia, investigative reports, interviews, and opinions. In English. You’re welcome. Find us on Instagram https://t.co/8wlZFqjFZE
Physics In History @PhysInHistory
579K Followers 0 Following Photos from the history of physics | © with mentioned Archives. Shared for educational purposes. Einstein portrait © Ullsteinbild. Subscribe for curated papers.
Ruhi Chess @Ruhichess
6K Followers 263 Following Chess is more than a game. It's a language that transcends borders, cultures, and time. Let's connect and explore human creativity together 💜
🔥Kareem Carr | Sta.. @kareem_carr
172K Followers 407 Following Stats PhD student @Harvard • Follow me if you’re curious about statistics and data science.
Continuum: Lifelong L.. @ContinuumAAN
15K Followers 331 Following The official CME review journal of the American Academy of Neurology. Includes Continuum Audio.
American Academy of N.. @AANmember
43K Followers 1K Following The official account of the American Academy of Neurology.
Jamir Pitton Rissardo @theneurolander
19K Followers 6K Following MD 🇧🇷 @UFSM_oficial @CooperNeuroRes | Neurology 🧠 | Writer ✍️ | Reviewer | Illustrator | Guitarist ♬🎸 World J Clin Cases editorial board member.
NeurologyLive® @neurology_live
9K Followers 677 Following Delivering healthcare professionals treating neurological diseases quality and relevant information to help achieve the best patient care possible. #MindMoments
Neurology Today @NeurologyToday
64K Followers 3K Following The official news source of the American Academy of Neurology, published by Wolters Kluwer.
Jeffrey Mervis @jeffmervis
2K Followers 61 Following Senior correspondent at Science magazine, where I cover science policy, large and small. All comments are my own.
Kailash Bhatia @kailashbhatia
6K Followers 2K Following Editor Movement Disorders Clinical Practise; Professor of Clinical Neurology, Queen Square, UCL; Chairman MSA Trust UK; Opinions my own
Amitabh Kant @amitabhk87
605K Followers 1K Following Sherpa @G20org, India. Former CEO @NITIAayog. Author. Key driver @incredibleindia @startupindia @makeinIndia
Vishal Gulati (I back.. @VishalGulati_
6K Followers 672 Following Specialist computational biology and cognitive automation VC. Not a fan of mouse click economy. Founded @RecodeVentures
Mathai Mammen @mmammen
2K Followers 347 Following CEO and Chairman Designate, FogPharma. prior Exec Comm JNJ, R&D, SVP R&D, Merck, founder SVP R&D Theravance Biopharma (TBPH), Innoviva (INVA)
Daphne Zohar @daphnezohar
22K Followers 886 Following Founder & CEO of @SeaportTX. Founding CEO & now Senior Advisor @PureTechH. I share biotech news & commentary. Co founder/host @BiotechCH. Board @IamBiotech
CMO Kerala @CMOKerala
765K Followers 73 Following Updates from the Office of Chief Minister of Kerala, Shri. Pinarayi Vijayan
internet hall of fame @InternetH0F
2.8M Followers 842 Following alt @TPayst | credit is given when original source is known. if no credit is listed, OP can DM us with credit request.
Drew Armstrong @ArmstrongDrew
31K Followers 3K Following Executive Editor, Endpoints News (@endpts). Got a tip? DM me for my Signal handle.
Zain Rizvi @zainrizvi
4K Followers 987 Following Senior health counsel @SenSanders @HELPCmteDems. Tweets are my own.
Steve Forbes @SteveForbesCEO
231K Followers 1K Following Chairman & Editor-In-Chief, Forbes Media. Host of the webcast, What’s Ahead. Co-Author of INFLATION with Nathan Lewis and Elizabeth Ames. Out April 19th.
Mark Church @backandacross
29K Followers 400 Following Cricket warbler, Chair of The Tony Church Pancreatic Cancer Foundation ..Richard Branson’s stunt double..every day is a fresh delivery 🏏🏏😉
Tom Holland @holland_tom
327K Followers 1K Following New history of Rome's heyday - Pax - out now! Dinosaur lover. Stonehenge Tunnel hater. A 'leading English cricketer' - The Times. Podcast: @theresthistory
Anjana Sankar @Asankar
5K Followers 2K Following IWMF 2024 Elizabeth Neuffer Fellow; @TheNational Abu Dhabi chasing stories of conflict and migration. Views my own@smead2 @PhilAlz @SFAckley @MariaGlymour @VincentPlanche @nvillain_alz @AlbertoEspay @KasperKepp @kathy_y_liu @seb_walsh “Deliberately chosen to minimise”. Simon, these are the data. Nobody like me has “chosen” to use them to do anything other than to be realistic about what treatment has achieved. I can understand why the companies want to make as much of them as they can, but we are scientists.
@smead2 @PhilAlz @SFAckley @MariaGlymour @VincentPlanche @nvillain_alz @AlbertoEspay @KasperKepp @kathy_y_liu @seb_walsh Of course the changes on absolute scales are important. What else do we have? Are you suggesting we just make stuff up? And, while MCIDs aren’t everything, they at least tell us that the effects of the drugs are effectively unnoticeable in an individual treated patient.
@smead2 @PhilAlz @SFAckley @MariaGlymour @VincentPlanche @nvillain_alz @AlbertoEspay @KasperKepp @kathy_y_liu @seb_walsh I think it’s called understanding the data and telling the truth, Simon. No need to bring any kind of falsity into this.
We argue that "language should be prudently restrained" about mAbs in Alzheimer's to avoid overstatement and false hope. We cite @SFAckley @MariaGlymour @VincentPlanche @nvillain_alz @AlbertoEspay @KasperKepp @kathy_y_liu @seb_walsh @ProfRobHoward researchgate.net/publication/38…
Brain biopsies on ‘vulnerable’ patients at Mount Sinai set off alarm bells at FDA, documents show - chilling report by @KatherineEban statnews.com/2024/05/01/bra… via @statnews
@MadhavThambiset @smead2 @ProfRobHoward @pash22 @AANmember No, you are correct in that making this claim is on thin ice. But the CDR does measure driving. This would be an amazing substudy: NNT to keep driving at 1.5 years.
It was a privilege for me/my @newmarkjschool students to publish our 2-year investigation into brain biopsies at Mount Sinai in @statnews. More soon on what we found.
Brain biopsies on 'vulnerable' patients at Mount Sinai set off alarm bells at FDA By @KatherineEban in @statnews. statnews.com/2024/05/01/bra…
@VidyaKrishnan Look at the timeline of when they knew, and then the number of trips Amit Shah made to Mysore to persuade JDS to sign up. And the reason it took that long? JDS refused to give up Hassan. Yeah, so many people were in on it
@MadhavThambiset Haha I know what you mean, and the driving is very “fluid” like a river of cars flowing past each other :) Luckily I was there on Election Day in Karnataka so very quiet as it was a holiday. It seemed like Thanksgiving day in the US !
@MadhavThambiset @smead2 @ProfRobHoward @pash22 @AANmember That was good. Gotta admit, took me a couple of reads.
@MadhavThambiset @CorriveauNick @smead2 @ProfRobHoward @pash22 @AANmember Yeah, NH or not would be a many year gap. (speculation!)
call sanju tomorrow, tell him you are the captain, let him pick people, have the seniors support him, surprise us agarkar, let’s get one trophy
@CorriveauNick @smead2 @MadhavThambiset @dcweisman @pash22 @AANmember Absolutely. The “time savings” arguments are not robustly supported by the trial data and are false promises that patients and families understandably latch onto. We have to be so careful if we want patients to make informed risk:benefit decisions about treatment.
@smead2 @MadhavThambiset @dcweisman @ProfRobHoward @pash22 @AANmember True maybe not "regaining" but even maintenance seems like a stretch and oversimplification. Even comprehensive neuropsych evals are not perfectly accurate tools to predict this. Very unwise to even suggest Lecanemab may allow for that with absolutely 0 supporting data
@MadhavThambiset @dcweisman @smead2 @ProfRobHoward @pash22 @AANmember Neurological and neuropsychological assessments are only proximal ways to assess whether an individual can drive. I would never trust testing alone. Thinking Lecanemab can grant this ability back (if revoked) is an oversimplification of a complex matter. psycnet.apa.org/record/2009-11…
OK, time to start the long journey home
So hard to keep colleagues, patients and the Alzheimer’s charities focussed on what the trial data actually show rather than what we’d all want to believe the drugs might be able to do.
Misleading to claim #donanemab or any amyloid lowering Rx will allow an #Alzheimer’s patient to continue to drive independently. Inserting the claim immediately outside a respected KOL’s quote also risks wrongly attributing this to them. Not a good look @ProfRobHoward @pash22
Finally made it to NIMHANS, Bangalore, to work on our India ENIGMA study. Congrats to all the new NIMHANS PhD students (Mekha, Aarthi, Gauthami) for presenting their wonderful PhD projects applying novel #AI methods to the India ENIGMA cohort datasets ! reporter.nih.gov/search/x2BnLSM……
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