Mizushima Lab (UTokyo) @MizLabUT
We are a group of researchers working on autophagy in the University of Tokyo. (This account is managed by young researchers in the lab.) molbiolut.jp/en/ The University of Tokyo Joined December 2019-
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【お知らせ】 件名:「小胞体」の名称の変更に関するパブリックコメントの募集 主催者:日本細胞生物学会*、日本生化学会、日本解剖学会、日本分子生物学会、日本遺伝学会(賛同順、*は提案学会) パブリックコメント募集サイト: jscb.gr.jp/app/uploads/20… 受付締切:2025年4月30日
Autophagic flux measurement: cargo degradation versus generation of degradation products. オートファジー活性評価における分解産物の定量の利点について説明しました。 sciencedirect.com/science/articl…
Autophagic flux measurement: cargo degradation versus generation of degradation products. The advantages of quantification of degradation products in the evaluation of autophagy activity were explained. sciencedirect.com/science/articl…
Rational engineering of lipid-binding probes via high-throughput protein-lipid interaction screening biorxiv.org/cgi/content/sh… #biorxiv_cellbio
[11/5~11/11 期間限定“0円購読”] これからの査読の話をしよう:eLifeの新しい査読システムから考える,研究評価の理想像(Alessio Bolognesi ✕水島 昇) doi.org/10.18958/7427-… Alessio…
「これからの査読の話をしよう:eLifeの新しい査読システムから考える,研究評価の理想像」 yodosha.co.jp/jikkenigaku/ar… 昨年からのeLife誌の新しい査読システムについて、Alessio Bolognesi博士と水島昇先生が語り合う対談記事です。来週月曜まで0円で記事購入いただけます。 #スマホで読める実験医学
[プレスリリース] 表面張力が損傷ミトコンドリアのオートファジーを促進する――オートファジーアダプターの相分離によるシート状液滴の意義―――医学系研究科・医学部 u-tokyo.ac.jp/focus/ja/press…
We simulated the formation of OPTN droplets on the membrane in mitophagy. The droplets could lead to the membrane connection. Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates | The EMBO Journal embopress.org/doi/full/10.10…
条件検討中 何度失敗してもめげずにキーデータを取得するに至った水島さん、おつかれさまでした!
条件検討中 何度失敗してもめげずにキーデータを取得するに至った水島さん、おつかれさまでした! https://t.co/HRUWNSG2o7
Optimizing condition... Thank you for your hard work, Mizushima-san, who persevered through multiple setbacks to obtain the key data!
Optimizing condition... Thank you for your hard work, Mizushima-san, who persevered through multiple setbacks to obtain the key data!
Supplementary Movie
Supplementary Movie https://t.co/2BUafZkqeO
Supplemantary Movie
Supplemantary Movie https://t.co/hJ2SvQ3wQ1
Noboru shows a 'MD simulation'. ATG9 vesicles move freely due to thermodynamic fluctuations. When they contact the OPTN droplet in the center of the screen, the ATG9 vesicles are captured and anchored to the droplet due to the wetting effect (Mizushima et al. unpublished)
Noboru shows a 'MD simulation'. ATG9 vesicles move freely due to thermodynamic fluctuations. When they contact the OPTN droplet in the center of the screen, the ATG9 vesicles are captured and anchored to the droplet due to the wetting effect (Mizushima et al. unpublished) https://t.co/oQyhwr11hW
水島さんによる"分子動力学シミュレーション"です。 ATG9小胞は、熱力学的振動により自由に運動しています。画面中央のOPTN液滴に接触すると、Wettingの効果により、ATG9小胞は液滴に捕獲されて係留されました(Mizushima et al. unpublished)
水島さんによる"分子動力学シミュレーション"です。 ATG9小胞は、熱力学的振動により自由に運動しています。画面中央のOPTN液滴に接触すると、Wettingの効果により、ATG9小胞は液滴に捕獲されて係留されました(Mizushima et al. unpublished) https://t.co/L2M7YzJIvO
Our new paper has been published in @embojournal! We demonstrated that capillary forces by autophagy receptor droplets on mitochondria is important for mitochondrial recognition and mitophagy. Congratulations, Zi! embopress.org/doi/full/10.10…
新しい論文が@embojournalに掲載されました!ミトコンドリア上のオートファジーレセプター液滴による毛細管現象が、ミトコンドリアの認識とマイトファジー誘導に重要であることを示しました。Yangさん、おめでとうございます! embopress.org/doi/full/10.10…
Hayashi-san won an Excellent Poster Presentation Award at the 16th Autophagy Research Meeting for Young Scientists. Congratulations!!!
I love Miz Lab families and many fun memories in Miz Lab❤️
We celebrated Mizushima Lab's 20th anniversary with a fantastic BBQ! Alumni reunited to share memories. Inspiring to see alumni—nurtured by Dr. Mizushima—thriving in diverse fields. The day was full of laughter and joy. Here's to Mizushima Lab's continued success!

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