Daniel Vera @_Daniel_Vera
Computational Biologist interested in aging, chromatin, gene regulation, genomic technologies | #rstats | @harvardmed | https://t.co/99DnnC9BLs Boston, MA Joined October 2013-
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Daniel Vera retweeted
Open Genes—a new comprehensive database of human genes associated with aging and longevity academic.oup.com/nar/advance-ar…
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Daniel Vera retweeted
Excited to release a new app, EagleC Explorer, in which you can detect and visualize SVs and enhancer hijacking on a Hi-C map, with only clicks of a button. Powered by machine learning models and works with Windows and Mac. biorxiv.org/content/10.110…
Daniel Vera retweeted
Recent @CellCellPress study claiming HERVK transcription drives senescence has a fundamental RNA-seq analysis problem. The results don't show HERVK elements with intact Env are derepressed, nor are they differentially expressed in senescent cells. 🧵 1/n cell.com/cell/fulltext/…
Daniel Vera retweeted
If you want to break into the machine learning field, you can't miss the best Linear Algebra course. And it's FREE! MIT's Professor Gilbert Strang is probably one of the best educators you'll ever meet. ocw.mit.edu/courses/18-06-…
Daniel Vera retweeted
Birth of a brain cell. Stem cell differentiating into a neuron: #neuroscience
Daniel Vera retweeted
Valuable #immunology cell atlas: #scRNAseq + paired B & T cell receptor seq for 330,000 tissue-resident immune cells across 16 human tissues. CellTypist: new & robust immune cells annotation algorithm, finding 101 immune cell types in 1,000,000 cells‼️ Why this is important👇🧵
Daniel Vera retweeted
Timely @jclinicalinvest review on metabolic changes in aging humans with specific focus on fat, muscle and liver. Take home message - the best and proven way to slow down aging is optimum nutrition and exercise. jci.org/articles/view/…
Daniel Vera retweeted
Excited to share our latest chrono-nutrition paper out today! cell.com/cell-metabolis…
Daniel Vera retweeted
A Black pastor was watering his neighbor's flowers while they were out of town. Then the police showed up — and arrested and charged him. n.pr/3e80bZK
Daniel Vera retweeted
The bizarre sea slug, Melibe viridis, uses its head as a net to catch food. Credit: Emeric Benhalassa
Daniel Vera retweeted
The expanding role for small molecules in immuno-oncology go.nature.com/3KkW9JT A new review covering small molecules targeting cancer metabolism, cytokine/chemokine and innate immune pathways and T cell checkpoints that could be complementary to PD1/PDL1 inhibitors
Daniel Vera retweeted
Understanding the logic behind logistic regression can provide strong insight into the basics of deep learning. I'm excited to share my visually-driven deep dive into this algorithm. 🧵
Daniel Vera retweeted
Another great study questioning the role of mutations in aging. Patients carrying germline mutations in MUTYH, a gene involving in DNA repair, have increased somatic mutation rates and more cancer. Yet they do not show signs of premature aging. nature.com/articles/s4146…
Daniel Vera retweeted
Over the years, the lab and I have come up with various materials for science process (writing, presenting, reviewing, etc.). Here they are, loosely organized in a Google Doc. Hope it is useful! docs.google.com/document/d/1jB…
Daniel Vera retweeted
We're starting a new technology sharing program for @cegs_ica! Sign up for free 'starter kits' for our NTT-seq technology, for simultaneous profiling of multiple chromatin marks in single cells. multimodalintegration.org/techsharing
Daniel Vera retweeted
Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging onlinelibrary.wiley.com/doi/10.1111/jo…
Daniel Vera retweeted
It is remarkable that all mammals age, yet our ancestors (reptiles, amphibians, fishes) have species that appear not to age at all. Why? One hypothesis I proposed 20 years ago is that all mammals age because of the dinosaurs. A short thread 🧵 1/4
It is remarkable that all mammals age, yet our ancestors (reptiles, amphibians, fishes) have species that appear not to age at all. Why? One hypothesis I proposed 20 years ago is that all mammals age because of the dinosaurs. A short thread 🧵 1/4
Daniel Vera retweeted
News and Views piece @NatureAging with @CyrilLagger on analyzing single-cell transcriptomics data to infer age-related changes in gene regulation. nature.com/articles/s4358…
Daniel Vera retweeted
excited to share an in-depth review of aging clocks or-more appropriate-methods to estimate biological age rdcu.be/cPR6u. Congratulations to Jarod Rutledge and Hamilton @hammy_oh
Daniel Vera retweeted
Very excited to show you our work on how the cohesin acetylation cycle controls the length of chromatin loops and architectural stripes @NatureSMB! 🤩 doi.org/10.1038/s41594…
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