Nicholas Cheang @_immunogeNIC
👨🏻🔬@SAlonsoGroup PhD Student & Hardcore Immunologist l 🔍DC-targeting & sarbecovirus vaccines | Immune cell bias: B cells 👑 (Ironically, not DCs). linkedin.com/in/nicholas-ch… NUS, Singapore Joined January 2022-
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Nicholas Cheang retweeted
#Immunology out now @ScienceMagazine After initial priming in the lymph nodes, mouse CD8 T cells undergo a second phase of stable interactions with dendritic cells that can preferentially stimulate those with a high-affinity for antigen. buff.ly/lCPsea3 By Jobinet al.
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3 days of hardcore B cells. Learnt alot from new research findings and the insightful scientific discussions during oral and poster sessions. Great experience and looking forward to more B cell science in future. 🤗 Thanks @KeystoneSymp for the amazing organizartion. #KSBcells25
Nicholas Cheang retweeted
Happy to share our latest work by @YYexin et al. on antibody-mediated control of endogenous retroviruses in mice. In the process, we found “natural antibodies” with broad reactivity against enveloped viruses. Here is how “panviral” antibodies work 🧵(1/) science.org/doi/10.1126/sc…
Very interesting read elucidating why the mRNA (and potentially other platforms) COVID-19 vaxx faces waning nAb. Which begs the qn, how do we design vaxx that promote LLPC generation and seeding?
Very interesting read elucidating why the mRNA (and potentially other platforms) COVID-19 vaxx faces waning nAb. Which begs the qn, how do we design vaxx that promote LLPC generation and seeding?
Nicholas Cheang retweeted
Check out our latest preview article in Cell @CellCellPress led by @MJMitchell_Lab PhD students @rohan_palanki + @hannahyamagata on @kedzierskalab's work identifying OLAH as a key enzyme that drives COVID-19 and other respiratory viral infections! Paper: cell.com/cell/fulltext/…
Nicholas Cheang retweeted
REVIEW @ImmunityCP Antibody modulation of B cell responses—Incorporating positive and negative feedback cell.com/immunity/fullt…
Loving the versatility of LNP technology. Hmmm, tying to my own work, how about conjugating the Clec9A mAb onto the LNP to deliver antigenic mRNA into cDC1? 🤔
Loving the versatility of LNP technology. Hmmm, tying to my own work, how about conjugating the Clec9A mAb onto the LNP to deliver antigenic mRNA into cDC1? 🤔
Nicholas Cheang retweeted
nature.com/articles/s4142… Happy to share our paper on Tfh specialization in antibody production on type-1 (virus) and type-2 immune responses (parasites, allergy). 1/11 #Tfhcells #germinalcentre #antibodies #immunology #bioinformatics. @kumar @IMM @FMUL @FilipaR @lgraca
Nicholas Cheang retweeted
1/ Increasing vaccine protection against #COVID. A/Prof @SAlonsoGroup @NUSingapore & A/Prof @LahoudMirei @MonashBDI have discovered a technique for prolonging immune response to #SARSCoV2 virus in pre-clinical models using an antibody construct. More: bit.ly/3yKN3Ek
1/ Increasing vaccine protection against #COVID. A/Prof @SAlonsoGroup @NUSingapore & A/Prof @LahoudMirei @MonashBDI have discovered a technique for prolonging immune response to #SARSCoV2 virus in pre-clinical models using an antibody construct. More: bit.ly/3yKN3Ek https://t.co/e3cnsTgHQq
Nicholas Cheang retweeted
Our new study just published in @CellRepMed shows that SARS-CoV-2 vaccine breakthrough infections (BTIs) have a positive effect on T cell responses! 1/8 cell.com/cell-reports-m… @SetteLab @Alba_Grifoni @profshanecrotty @P1RAD @TertuAPN @ljiresearch
Nicholas Cheang retweeted
Delighted to celebrate our latest publication with A/Prof Sylvie Alonso @SAlonsoGroup on dendritic cell-targeting of SARS-CoV-2 antigens for durable and protective immunity. A fantastic collaboration between @MonashBDI and @NUSingapore. doi.org/10.1016/j.ymth…
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358 Followers 288 Following Assistant Professor at Duke-NUS. Interested in coronaviruses and their interactions with cells. All views are my own.
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121 Followers 89 Following Viral host-pathogen interactions and developing subunit vaccines and antivirals are what we love. Led by @NUSMedAlonsoS. Tweets by lab members!
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Adrian Kang @AdrianKang19
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Jonathan Markham @Jonathan428692
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geraldine🦠 @tinyroundblobs
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Mike Honey @Mike_Honey_
18K Followers 47 Following Data Visualisation and Data Integration specialist - Melbourne, Australia https://t.co/U523OiVeXr Support my projects by sponsoring me on Github
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91K Followers 73 Following Researching #SARSCoV2, SARS-CoV, MERS-CoV, Dengue, Zika, and human norovirus at the University of North Carolina. Shared laboratory account.
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Mike Mitchell @MJMitchell_Lab
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