Preethi Srinivasan @srinipr4
Joined May 2013-
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Published today! We used targeted #MSKimpact tumor sequencing data to infer genetic ancestry and identify associated somatic features in ~50,000 patients. Lots of interesting methods and findings, but I will focus on one. 🧵 @MSKCancerCenter (1/10) aacrjournals.org/cancerdiscover…
Online today! More to say later, but for now huge congratulations to @kanikaarora316 @chaiband @CDebyaniPhD and everyone involved in this important research! #MSKimpact @MSKCancerCenter 🧬
Online today! More to say later, but for now huge congratulations to @kanikaarora316 @chaiband @CDebyaniPhD and everyone involved in this important research! #MSKimpact @MSKCancerCenter 🧬
And check out the new portal that goes with this paper: signaldb.org! Think of it like @gnomad_project but for germline variation in cancer. It was a pleasure building this with @chaiband @srinipr4 @MFBerger1 @BarryTaylorLab and our usual posse @gaojj, Onur and Xiang
And check out the new portal that goes with this paper: signaldb.org! Think of it like @gnomad_project but for germline variation in cancer. It was a pleasure building this with @chaiband @srinipr4 @MFBerger1 @BarryTaylorLab and our usual posse @gaojj, Onur and Xiang
Very excited to see this finally out! Incredibly grateful and proud to share this work which has always been very close to my heart!
Very excited to see this finally out! Incredibly grateful and proud to share this work which has always been very close to my heart!
Following the departure of four stellar postdocs (@huzheng1, @caswell_jin, @seoaneja, Kasper Karlsson) who have launched independent careers in the past year, the Curtis Lab (med.stanford.edu/curtislab.html) is recruiting postdocs and computational staff scientists.
Happy to share my Feature Article @eLife — a call to expunge non-inclusive terms to make science inclusive for all #inclusivescience #EDI #scicomm #AcademicTwitter elifesciences.org/articles/65604 🧵⬇️
Our (co-inventors @McLellan_Lab) COVID-19 vaccine (spike delivered by @moderna_tx's mRNA) was just injected into the 1st human in phase 1 trial, only 66 days after viral sequence release... a testament to rapid vaccine development for emerging diseases🦠💚 niaid.nih.gov/news-events/ni…
🚨Urgent🚨@StanfordMed @StanfordHealth is performing 1000 tests for #COVID19 a day for Bay Area hospitals, but is running low on critical reagents. If your lab is in the area and can donate any of the following please DM. Thank you!
The Biogen cluster is a cautionary tale for anyone still considering conferences/large meetings over the coming weeks. At this point we all have enough information. Organizers: cancel/reschedule/go remote, or any transmissions are on you. bostonglobe.com/2020/03/11/nat…
Our paper is out! 😊 Showcasing the complexity of #mutationalsignatures A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies @NatureCancer 👇 1/ nature.com/articles/s4301…
Great tweetorial from my new colleague Sebas. Check out his new work CNApp!
Looking back as this decade is coming to a close: cBioPortal went from 4 cancer studies to >200, and we added countless new features. Thanks to #opensource, #TCGA, #NCIITCR, #HTAN, @AACR, @PCF_Science, @SU2C, @BCRFcure. Travel back in time @waybackmachine: web.archive.org/web/2011090100…
Ever had an MMR-P cancer turn out to be MSI-H and have no explanation? Read our brand new systematic analysis on the sensitivity of MMR IHC in a pan-cancer cohort of 443 MSI-H tumors in @ModernPathology : go.nature.com/2QaRoH3 Example and take home points below 👇
Great figure illustrating mechanisms of resistance to CDK4/6i form Dr. Jeselsohn #SABCS19 from @DanaFarber #bcsm
This week at #SABCS19, MSK investigators shared the latest in #breastcancer detection and screening, immunotherapy, and the underlying causes of resistance to targeted therapies, among other topics. Catch up here. bit.ly/2PkcWl7
Perspective: Machine learning has the potential to be extremely useful in medicine, particularly in the interpretation of medical images. But it also has inherent limitations, especially when it comes to diagnosing early-stage cancer. nej.md/38tpLB8
Major @OncoKB release & milestone people! We've now curated >5000 cancer alterations! & added a registration option (if you want to download data or use our API) to let us get to know our @OncoKB community better. Visit oncokb.org or via @cbioportal & stay tuned!
nice review by @BirsoyOzge on tumor-normal sequencing cell.com/trends/cancer/…

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