Ku-Lung Hsu @Hsu_Lab_UVa
Ku-Lung (Ken) Hsu is an Associate Professor of Chemistry at the University of Texas Austin hsulab.com Austin, TX Joined July 2017-
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Happy to share our review on the exciting frontier of covalent chemistry aimed at non-cysteine residues — expanding the toolbox for ligand discovery and chemical biology. Congrats to Gibae Kim from my group! pubs.acs.org/doi/10.1021/ac… @CovalentMod @UTChemistry @UTAustin
Human PTGR2 Inactivation Alters Eicosanoid Metabolism and Cytokine Response of Inflammatory Macrophages | ACS Chemical Biology pubs.acs.org/doi/full/10.10…
Check out our work on protein editing!
Thrilled to share our new covalent AKR1C3 inhibitor targeting a non-catalytic tyrosine (Y24) with proteome-wide selectivity! An enabling tool for probing metabolism in hormone-driven cancers. Big congrats to Justin Grams from my team! pubs.acs.org/doi/full/10.10…
Exciting new work from @Hsu_Lab_UVa developing #covalent inhibtors that target tyrosine #SuTEx #ABPP #Chembiol
Exciting new work from @Hsu_Lab_UVa developing #covalent inhibtors that target tyrosine #SuTEx #ABPP #Chembiol
Finishing the year with a review on applications of intact and native protein analysis for chemical proteomics. Congrats to postdoctoral fellow Alexis Edwards from my group @UTChemistry @TexasScience @UTAustin sciencedirect.com/science/articl…
Congrats to my team @UTChemistry for developing sulfonyl-azoles as tyrosine-reactive electrophiles. Thank you to @WelchFoundation for the support. …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…
We are excited to announce that Kurtis Carsch is joining our department! cm.utexas.edu/news/entry/kur…
After 11 great yrs @DukeU, the Hargrove Lab is starting a new chapter @chemuoft & @UTM ! We are deeply grateful for everyone at Duke who has supported us, esp. in @DukeChemistry @dukebiochem, and the NC RNA & ChemBio communities💙 Look for more on our Canadian adventures soon!🇨🇦
Upcoming webinar with GlycoNet investigator Dr. Lara Mahal! @glycocode #glycotime #glycomics
Upcoming webinar with GlycoNet investigator Dr. Lara Mahal! @glycocode #glycotime #glycomics
I'm very excited to share the news of my promotion. Much of the credit goes to the trainees that drove the research forward, and the invaluable mentorship that I received along the way from Michael Hecht, @davidrliu, @KapoorLab_RU, my Princeton colleagues, and many others!
I'm very excited to share the news of my promotion. Much of the credit goes to the trainees that drove the research forward, and the invaluable mentorship that I received along the way from Michael Hecht, @davidrliu, @KapoorLab_RU, my Princeton colleagues, and many others!
Awesome news! Congratulations @KleinerLabRNA!!
Awesome news! Congratulations @KleinerLabRNA!!
A big congratulations to Dr. Homan @RickHoman4!!! Fabulous job! Rick is our 2 of 2 first Ph.D’s! Thank you @Michael_A_Erb @LabWiseman @SchultzLabOHSU and Pat Griffin for serving on his committee
We're honored to host Yi Tang of @uclachem, this year's Vista Chemical Company Regents Endowed Memorial Lectureship in Organic Chemistry speaker.
Had tons of fun hearing good science at the 2024 Drug Discovery Chemistry meeting and also hanging out with friends Nir London, @Hsu_Lab_UVa @Michael_A_Erb @FleurMFerguson, Luke Lairson, and not pictured but also Brent Martin, @_chrisgparker_ @HuangMia !
Apply now for the 2025 Mark Foundation Emerging Leader Award! Grants are awarded to early-career investigators in US and Canada for projects addressing unmet needs in cancer research. Deadline to apply is April 29. For more information, please visit bit.ly/3Iw678s
Integration of DOS with PAL-based chemoproteomics from the Cravatt Lab. Further highlights the power of stereochemically matched probes to ID ligandable proteins. biorxiv.org/content/10.110…
Excited to share the final version in @nchembio. Lots more mechanistic insights & characterization, including our inhibitors disrupt PPIs with mTOR components & induce lysosomal degradation of SLC15A4, & more. A promising target for autoimmune conditions. nature.com/articles/s4158…

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