Jacob Søby @JacobSoeby
MD, PhD-student, Department of Cardiology, Gødstrup Hospital, Aarhus University. Myocardial perfusion imaging & chronic coronary syndrome Joined October 2018-
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Calcium Scoring Improves Clinical Management in Patients With Low Clinical Likelihood of Coronary Artery Disease @lostrasmussen @mortenboettcher @SimonWinther5 @SamEmil @JuhaniKnuuti @pamelasdouglas @BFoldyna jacc.org/doi/epdf/10.10…
The Euro Society of Hypertension recently upgraded B-blockers to first-line Rx In the Lancet, writing w Drs Messerli and Bangalore, we argue against this mostly convenience recommendation Link free to Dec 2 authors.elsevier.com/a/1hw4aV-4XL4Tu #CardioTwitter #neurotwitter @kaulcsmc
Appreciate the great editorial @Heart_BMJ from @marcusflather et al. on our novel ExECG model for pre-test assessment of stable chest pain patients. 📖: dx.doi.org/10.1136/heartj… Back to the future!🚀 @mortenboettcher @SimonWinther5 @JuhaniKnuuti @cvrints @SamEmil
PhD student Lene N Andreasen presented the OCTOBER Trial showing superiority of using OCT in guiding complex bifurcation PCI and had simultaneous NEJM publication. Great achievent Lene and congratulations to the whole OCTOBER organisation. 👏👏👏 DOI: 10.1056/NEJMoa2307770
Late-breaking @ #ESCCongress: similar moderate sensitivities but higher specificity of PET #cvNUK by 82Rb vs. 15OPET against invasive FFR. Importantly, both tracers had high sensitivities against severe stenosis with potential of causing myocardial ischemia. 🔴: 82Rb 🟢: 15O
Of press: a novel exercise ECG-weighted clinical likelihood model improves discrimination and potentially management of de novo chest pain patients. 📖: @Heart_BMJ Huge 🙌🏻 to @SimonWinther5 @mortenboettcher @SamEmil @JuhaniKnuuti @cvrints ➕Koen Nieman and David Newby.
Exited for the incoming results @escardio 2023 📍Amsterdam. @ @SimonWinther5 @mortenboettcher @larsgormsen @WestraJelmer @h_evald @SalmaRKarim @MetteNyegaard
Exited for the incoming results @escardio 2023 📍Amsterdam. @ @SimonWinther5 @mortenboettcher @larsgormsen @WestraJelmer @h_evald @SalmaRKarim @MetteNyegaard
Out in @Heart_BMJ: additional use of an acoustic rule-out device show potential to downgrade clinical likelihood of obstructive #cvCAD.🫀 @lostrasmussen @AshkanEftekhar1 @WestraJelmer @mortenboettcher @SimonWinther5 @h_evald heart.bmj.com/content/heartj…
How do different pretest probability models for obstructive CAD perform in a large cohort of patients referred for #yesCCTA? Interesting study from @SimonWinther5 et al. demonstrating the research potential of the large Western Denmark Heart Registry
How do different pretest probability models for obstructive CAD perform in a large cohort of patients referred for #yesCCTA? Interesting study from @SimonWinther5 et al. demonstrating the research potential of the large Western Denmark Heart Registry
Proud and happy to have defended my PhD thesis!💥 A big thanks to @mortenboettcher, @SimonWinther5, @DANNICADtrial patients and collaborators and friends and family for support over the years! Now: 🍻, then continuing the search for optimal handling of chest pain patients #cvCAD
2.2 Liters
Amazing Day at the Erasmus MC with the #OHDSI community discussing the foundation for personalized #surgery #ColorectalCancer
Interesting study with data from 5143 patients with #coloncancer regarding the risk factors for compromised specimen quality & the difference on quality between #laparoscopic and #openresection. Watch the video abstract: bit.ly/2Y1En5x @IsmailGogenur @RasmusVogelsang
Inden SP havde overlægerne i gennemsnit 2,91 patienter pr. time i ambulatorierne. Ni måneder efter SP nåede kun 2,31 patienter gennem ambulatorierne i timen. Et fald på 21 procent. Se @Overlgeforening rapport her: ecamp.zornig.dk/t/r-E3483649D5… #sundpol
Just published great paper! Describes how change of practice (small bites) at a single center was associated with a reduced rate of fascial dehiscence and incisional hernia. link.springer.com/article/10.100…
Just announced that this afternoon's speaker at #zealandsurgicalforum Henrik Kehlet will be portrayed on an official Danish postage stamp. Well deserved!! Looking forward to the presentation by this living legend and founding father of #ERAS dagensmedicin.dk/tre-faglige-fy… @cssdenmark
Interesting results on immune checkpoint inhibition! Challenges remain for the majority of CRC patients with pMMR and low mutational burden...
Interesting results on immune checkpoint inhibition! Challenges remain for the majority of CRC patients with pMMR and low mutational burden...
Really impressive results from @PeterMacCC! Would be interesting to use the tumoroid assay for evaluating other neoadjuvant immune enhancing interventions in colorectal cancer @cssdenmark #colorectalresearch
Really impressive results from @PeterMacCC! Would be interesting to use the tumoroid assay for evaluating other neoadjuvant immune enhancing interventions in colorectal cancer @cssdenmark #colorectalresearch
Soon Margulis @MargulisSo38648
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33 Followers 84 FollowingThe Dan-NICAD trials @DANNICADtrial
218 Followers 426 Following #DANNICAD | Danish study of Non-Invasive testing in Coronary Artery Disease | Advanced imaging in #cvCAD | #yesCCT #whyCMR #cvNUK #FFRCT #QFRMatters of the Heart .. @MattersoftheH14
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Really good point by Gary Mintz re PREVENT trial- does it make sense to do 803PCIs to prevent 12 cardiac events, of which only 5 were cardiac death / tv-mi #TCTAP2024 @summitmd_cvrf @dukwoo_park @Hragy @thiele_holger @ziadalinyc @djc795 @SukhNijjer @KardiologieHH @DFCapodanno…
No rest for the ORBITA team! Recruitment is going strong for ORBITA-FIRE which is being led by @fiyyazAJ. Thank you to @kliokon and the Essex CTC a fantastic case this week @DrKeeble @Dizzledavies73
Out in @GenomeMedicine: Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease. 📖: link.springer.com/content/pdf/10…
1/4 Just publ in the Lancet our updated network meta-analysis of imaging-guided (OCT or IVUS) vs. angio-guided PCI across the spectrum of CAD. With 22 RCTs and 15,964 pts this is the 1st study to demonstrate that imaging reduces all-cause death (by 25%), as well as all MI (17%).
On February 1st, I will assume my new position as Professor (Chair) in Clinical Physiology and Nuclear Medicine at the Department of Clinical Medicine, Aarhus University, and the Department of Nuclear Medicine & PET Center, Aarhus University Hospital.
Excited to be presenting this 18,200 patient late breaking clinical trial at #ACC24
Can we clear arterial atherosclerotic plaques? The ACC.24 Late-Breaking Clinical Trials have been announced. My highlight is the large, phase 3, multicenter, double-blind, randomized, placebo-controlled AEGIS-II trial, a study of CSL112 (apolipoprotein A-I) infusion in patients…
Utility of 82Rb and [15O]H2O PET myocardial perfusion imaging in challenging (high risk) patients. Thank you Ibrahim Danad and Roel S. Driessen for a nice editorial about our work in @JNCjournal #15Owater #CardiacPET @AUHdk @larsgormsen @HJHarmsPhD sciencedirect.com/science/articl…
By additional quantification of myocardial blood flow with Rubidium PET, 1 in 2 patients with obstructive #cvCAD but normal visual stress perfusion #cvNUK are correctly reclassified @lostrasmussen @DANNICADtrial #AHAJournals ahajrnls.org/420Q3qR
Out in @journalCCT: Optimal diagnostic approach for using CT-derived quantitative flow ratio in patients with stenosis on coronary computed tomography angiography. sciencedirect.com/science/articl…
Importantly, using a lesion-specific CT-QFR approach has superior discrimination of hemodynamically obstructive CAD compared to a most distal CT-QFR approach. More to come!🚀
Out in @journalCCT: Optimal diagnostic approach for using CT-derived quantitative flow ratio in patients with stenosis on coronary computed tomography angiography. sciencedirect.com/science/articl…
📕Off press @CircAHA: Cardiovascular Imaging. Impact of Absolute Myocardial Blood Flow Quantification on the Diagnostic Performance of PET-Based Perfusion Scans Using 82Rubidium. ahajournals.org/doi/10.1161/CI…
Calcium Scoring Improves Clinical Management in Patients With Low Clinical Likelihood of Coronary Artery Disease @lostrasmussen @mortenboettcher @SimonWinther5 @SamEmil @JuhaniKnuuti @pamelasdouglas @BFoldyna jacc.org/doi/epdf/10.10…
The REVIVED viability study is now out in print.. Extent of viable myocardium was NOT associated with patient outcomes.. but amount of scar was! @JAMACardio jamanetwork.com/journals/jamac…
Myocardial viability testing does not identify patients with ischemic cardiomyopathy who benefit from PCI. Findings suggest that the extent of dysfunctional yet viable myocardium was not associated with revascularization outcomes. ja.ma/3QFH1vr @REVIVED_BCIS2
PINCH ME PLEASE! Over the moon and beyond to announce the collab with @soudalquickstep for 2024! Got the massive opportunity to design their kits for the upcoming season 🥹 2024 let's go 🙏 📸 Wout Beel
Preoperative multimodal prehabilitation before elective colorectal cancer surgery in patients with WHO performance status I or II: randomized clinical trial ➡️doi.org/10.1093/bjsope… In this randomized clinical trial comparing patients undergoing 4 weeks of multimodal…
Novel clinical likelihood models improve discrimination and prognostication of obstructive #cvCAD in an external 🏴 cohort. 📍: @Open_HeartBMJ 📖: openheart.bmj.com/content/openhr…
@UKheartresearch @AishSinha1 @CircIntv @AHAScience @CircAHA @The_MRC @kingscardio @GSTTresearch @DrHaseebRahman1 @ColletCarlos @JEscaned @hollymorgs @NSmilowitzMD @iamritu @LermanAmir @habib_samady @drTPH … and thoroughly deserved winner of the Samuel A Levine Early Career Clinical Investigator Award #AHA23. Well done @AishSinha1 !!