William A. Wallace, Ph.D. @drwilliamwallac

A less commonly talked about function of some vitamins is their role as hormones or "hormone-like" compounds in the body. Vitamins are not just essential nutrients; they also play roles similar to hormones. For instance, vitamin D and vitamin A have hormone-like actions due to…

Eight-Week Creatine-Glucose Supplementation Alleviates Clinical Features of Long COVID #creatine pubmed.ncbi.nlm.nih.gov/38684388/

This graphic and description are not able to be close to exhaustive on the amount, depth, and nuance of information surrounding vitamin D. Concerning vitamin D deficiency, clinical deficiency most prominently affects the neuromuscular and skeletal systems. The most visible…

Summary of causes of vitamin D deficiency and diseases and disorders associated with vitamin D deficiency. Note: not all diseases associated with vitamin D deficiency are a direct cause of vitamin D deficiency. Vitamin D deficiency can be a byproduct of disease or an "unhealthy…

Sleep: A “Light” Guide. An estimated third of American adults don’t get the recommended amount of sleep. One should generally target 7-9 hours of sleep per night. Disclaimer: This post is not meant to diagnose or treat sleep disorders. Before beginning any regimen to treat what…

Polyphenols are bioactive compounds that are naturally present in foods of plant origin. When ingested (in appropriate amounts), these compounds protect the body (some in a tissue-specific manner) against different physiological and environmental toxins and disease risk factors…

Nutritional Neuroscience: Micronutrients in Neurotransmitter Synthesis and Metabolism- A Simple Illustration. Understanding the complex interplay between vitamins, minerals, and neurotransmitter pathways highlights the foundational role of nutrition in cognitive health and…

The current European and American recommendations concerning physical activity indicate: *150 min per week of moderate physical exercise (30 min/day, 5 days/week) or *75 min/week of physical exercise of vigorous intensity (15 min/day, 5 days/week). *Practicing physical exercise…

Depressive Disorders: A “Light” Guide. Disclaimer: This post is not meant to diagnose or treat depression. Before beginning any regimen to treat what you may think may be clinical depression, consult your primary medical doctor. Consult your primary medical doctor if you are…

A follow-up of an earlier post. Food sources of nutrients that support mitochondrial health. Of course, it is worth noting that most research (yesterday's post referenced that most is preclinical in vitro (cell) and animal data) surrounding the topic of nutrition on…

Dietary taurine intake may contribute to the maintenance of muscle strength during aging. Findings: *⃣ Higher taurine intake is correlated with less decline in muscle strength among those aged 65 and older. *⃣ ~365 mg of dietary taurine daily in the high consumers. Food sources…

🔬 The Role of Micronutrients in ATP (energy) Production 🔬 Micronutrients, although required in minute quantities, are indispensable catalysts in the metabolic pathways that convert food into energy. These pathways, include glycolysis, the Krebs cycle, and the electron…

This post does not suggest that vitamin deficiencies are causal to all cases of depression, or even that they play a primary role in some cases of depression. This post is meant to convey ways in which vitamin deficiencies can contribute to the etiology of depression [this may be…

The Link Between Vitamin D and Aging: A Multidimensional Perspective Vitamin D plays a multifaceted role in modulating complex biological processes associated with aging. This graphic is meant to depict the relationship between Vitamin D levels and the primary, integrative, and…

The multifaceted impact of exercise beyond only skeletal muscle adaptations: the systemic metabolic benefits of physical activity. Regular exercise has emerged as a known regulator of insulin sensitivity and systemic metabolism, mitigating the risk of chronic metabolic diseases…

A recent systematic review published in GeroScience highlights the multifaceted effects of glycine on various human physiological systems. The review consisted of 50 studies (most of which were RCTs) with oral ingestion of glycine being the most common mode of delivery. Trials…

🧠🪨 Minerals are not just elements on the periodic table; they are crucial intermediates of our neurological well-being.

Myokines are a specialized subset of peptides (acting as signaling molecules) produced by muscle fibers in response to exercise. These molecules have emerged as pivotal players in the crosstalk between muscle and various organ systems. The scope of myokine action extends across…

Melatonin has known antioxidant properties in the brain and in the gut. More recently, it has been suggested the same can be said about its protective effects in skeletal muscle. Of note, this post is not meant to outline or suggest generalized protocols regarding supplemental…

💊 Dietary Supplements should not be used for forming a solid foundation by which we can build and accurately measure general health. However, they are capable of addressing inadequacies, deficiencies or holes to be addressed regarding health - and do so in a convenient, and…