Christopher Garris @csgarrix
Assistant Professor Mass General @MGHCSB @MGHPathology and Harvard Med @harvardmed specializing in Immuno-Oncology with a focus on Dendritic Cells. Boston, MA Joined November 2013-
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Christopher Garris retweeted
📣New paper out in Methods in Molecular Biology @RossWWard44 This protocol details how to generate mRNA vaccine formulations with lipid nanoparticles and evaluate their immunogenicity, antigen cross-presentation, and CD8⁺ T-cell responses. #mRNAVaccine link.springer.com/protocol/10.10…
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Christopher Garris retweeted
Our paper made the September cover of @NatImmunol! 🎉 Aren’t dendritic cells beautiful? 😍 SEM shows pDCs transitioning into cDC2-like cells. Huge congrats to the whole team! 👏 🔗 nature.com/ni/volumes/26/…
Christopher Garris retweeted
Congrats @propriodon #NicoleLester @Ella_Perrault #JenniferSu @GongDennis #CarinaShiau @PhuongTTNguyen1 and team! We are excited to share this story that we’ve been working hard on for several years. More to come soon. Stay tuned
Congrats @propriodon #NicoleLester @Ella_Perrault #JenniferSu @GongDennis #CarinaShiau @PhuongTTNguyen1 and team! We are excited to share this story that we’ve been working hard on for several years. More to come soon. Stay tuned
Christopher Garris retweeted
Overcoming immune suppressive myeloid cell barriers in #BladderCancer. Presentation by @csgarrix @MGHPathology. #BCANTT25 written coverage by @chavarriagaj @UofT on UroToday > bit.ly/4l3ruRP @BladderCancerUS
Christopher Garris retweeted
T cells do the heavy lifting when it comes to the anti-tumor action of checkpoint immunotherapy. But do antibodies play a role too? That’s the question @Yile_Dai looked to answer in his thesis work, out today in @Nature! 🧵below nature.com/articles/s4158…
Christopher Garris retweeted
🚨 A warning from @NIH Do not use “substantial” #AI generated content in your grants! “the detection of AI is identified post award, NIH may refer the matter to the Office of Research Integrity….” NIH is also limiting grant submissions to SIX per year. grants.nih.gov/grants/guide/n…
Christopher Garris retweeted
Discovery of a pH sensor that regulates inflammation. Zhou and Medzhitov provide a mechanistic tour-de-force in defining how BRD4 links changes in pH to inflammatory gene expression. Kudos to the authors on this exciting finding. sciencedirect.com/science/articl…
Christopher Garris retweeted
#EpigeneticPower! Our #NewPaper @ImmunityCP shows that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2, blocking #IL10! authors.elsevier.com/a/1lS0g3qNrU-i…
Christopher Garris retweeted
A new function for an ancient innate immune stimulus. Zanoni et al report that oxidized lipids control IL-10 expression, impacting host defense and disease. Kudos to the authors on this important discovery sciencedirect.com/science/articl…
Christopher Garris retweeted
🔥🔥🔥Endogenous oxidized lipids regulate polycomb complex to epigenetically control IL10 level! Congrats to @Lo_Zanzi and Marco! What an amazing discovery👏 honored to play a tiny part in this story 👇authors.elsevier.com/c/1lS0g3qNrU-i…
🔥🔥🔥Endogenous oxidized lipids regulate polycomb complex to epigenetically control IL10 level! Congrats to @Lo_Zanzi and Marco! What an amazing discovery👏 honored to play a tiny part in this story 👇authors.elsevier.com/c/1lS0g3qNrU-i…
Christopher Garris retweeted
How a bacterial strain from patients who responded to immunotherapy, when transferred to mice, revved up the immune response vs. tumors nature.com/articles/s4158…
Christopher Garris retweeted
Very excited to share our review on "Metabolites as agents and targets for cancer immunotherapy" in @NatRevDrugDisc! read it here: rdcu.be/etAMD @SpringerNature @KlinPharm
Christopher Garris retweeted
Cancer vaccines will be a big part of the future of immunotherapy. A new, super review @TheLancet thelancet.com/journals/lance…
Christopher Garris retweeted
“Why stop now, when we haven’t yet realized immunotherapy’s full potential?” In a new @NatRevDrugDisc interview, @mellmani, PhD, President of Research at PICI, shares what’s next in #CancerImmunotherapy—from curative cell therapies to smarter T cells. Read more:…
Christopher Garris retweeted
(1/2) A very exciting milestone for @VolastraTx and the field of #Chromosomal_Instability. Early escalation data for our KIF18A inhibitor, VLS-1488, show excellent safety and promising efficacy in heavily pre-treated ovarian cancer patients. businesswire.com/news/home/2025…
Christopher Garris retweeted
We're excited to share that Dr. Andy Minn will return to MSK as the inaugural Chair of MSK’s new Immuno-Oncology Program in August. This is a full-circle moment for Dr. Minn, a renowned physician-scientist, who completed his postdoctoral training with Dr. Joan Massagué,…
Christopher Garris retweeted
STAT5 and STAT3 balance shapes DC function and tumor immunity @Nature nature.com/articles/s4158…
Christopher Garris retweeted
We tested the feasibility and immunogenicity of a personalized neoantigen vaccine + PD-L1 blockade in #bladdercancer including the adjuvant setting. nature.com/articles/s4301… @JonAnker1 @BhardwajLab @urotoday @Uromigos @TischCancer @FaltasLab @NatureCancer @BladderCancerUS
Christopher Garris retweeted
Online Now: TAMing immunity through an unexpected source dlvr.it/TKVRC4
Christopher Garris retweeted
Out now in @CD_AACR and featured #AACR25, we show a combinatorial approach to overcome resistance to RAS(ON) inhibitor monotherapy in PDAC, where use of CDK4/6 inhibitor Palbociclib and CD40 agonist drives therapy-induced senescence & CD4 T cell-dependent tumor-immune equilibrium
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