TregCell Radar @TregCellRadar
Joined May 2013-
Tweets715
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TregCell Radar retweeted
I'm a neuroscientist. Here are 4 surprising things that protect your brain from premature aging: 1. Brushing your teeth Chronic gum disease is linked to higher risk of dementia and faster progression.
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TregCell Radar retweeted
This is very emotional to me. Congrats to Sangamo and my former TxCell team. Forever first! businessinsider.com/exclusive-sang…
TregCell Radar retweeted
We conducted a phase I #clinicaltrial with CoVac-1, our #peptide-based #COVID19 #vaccine candidate for induction of SARS-CoV-2 T cell immunity. Our observations support the presently ongoing phase II trial for patients with B cell/antibody deficiency. Here’s what we found:
We conducted a phase I #clinicaltrial with CoVac-1, our #peptide-based #COVID19 #vaccine candidate for induction of SARS-CoV-2 T cell immunity. Our observations support the presently ongoing phase II trial for patients with B cell/antibody deficiency. Here’s what we found:
TregCell Radar retweeted
Brilliant! #Regulatory #Tcells (#Tregs) expressing #TNFR2 suppress #MultipleSclerosis in a #mouse #model (EAE) #LOCALLY and at the #PEAK of the #disease!!! #Systemic anti #TNF exacerbated disease. @Sorbonne_Univ_ @Inserm @PNASNews #immunologymatters pnas.org/content/118/13…
TregCell Radar retweeted
new finding. anti-PD1 reactivates Tregs too in tumors. #cancer #Immunotherapies #Immunology The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies | Nature Immunology nature.com/articles/s4159…
PD-L1 – PD-1 interactions limit effector Treg cell populations at homeostasis and during infection biorxiv.org/content/10.110…
TregCell Radar retweeted
COVID vaccine company @moderna_tx & @unmc researchers (@hegendel) report lipid nanoparticles containing granulocyte-macrophage colony-stimulating factor mRNA (Gm-csf mRNA) - to peripherally induce Tregs - offers neuroprotection in models of #Parkinsons sciencedirect.com/science/articl…
New agonist MAb resolves chronic inflammation bioworld.com/articles/50592…
TregCell Radar retweeted
Wanted to drill down a bit more about the importance of the T-cell response to SARS-CoV-2 to give you more reassurance of enduring protection from vaccines (even against variants). Technical article here but CD4/CD8 cells have role in both acute infection cell.com/cell/pdf/S0092…
TregCell Radar retweeted
On behalf of the entire #COVaRiPAD team, we are thrilled to announce our preprint reporting humoral responses after BOTH doses of mRNA-based SARS-CoV-2 vax in 133 pts w/ chronic inflammatory diseases (CID) and 53 immunocompetent controls: medrxiv.org/content/10.110…. 1/
TregCell Radar retweeted
Depleting #Tregs with an #ICOS-specific antibody increases #Tcell function, delays tumor growth, and improves efficacy of #ImmuneCheckpointBlockade. Learn more: @rcasainson @biomiha #KY1044 #PDL1 bit.ly/2WrQ8ml
TregCell Radar retweeted
An #mRNA #vaccine that suppresses #MultipleSclerosis!! #Tolerance and #immunity are just sides of a coin. Could a byproduct of the #COVID19 #pandemic be the power to control our #ImmuneSystem w/ unprecedented #precision? #immunologymatters #thefutureishere science.sciencemag.org/content/371/65…
TregCell Radar retweeted
New exciting collaboration work with @aaronmring lab reveals diverse and functional autoantibodies in #COVID patients. Our findings provide clues for why COVID affects many organs, induce range of symptoms that are long lasting. Thread (1/n) medrxiv.org/content/10.110…
TregCell Radar retweeted
Broadly-targeted autoreactivity is common in severe SARS-CoV-2 Infection medrxiv.org/cgi/content/sh… #medRxiv
TregCell Radar retweeted
Foxp3 Instability Helps tTregs Distinguish Self and Non-self frontiersin.org/article/10.338…
TregCell Radar retweeted
At #CellSeries20 (Oct. 6-7), Sangamo’s Céline Dumont will present preclinical data from our CAR-Treg cell therapy program, supporting the initiation of the STEADFAST clinical study. Learn more: bit.ly/3hYkNjj @CellCultureConf
TregCell Radar retweeted
And it's finally out! If you thought that CAR-Tregs would be just like CAR-T cells, think again. Great collaboration with @SangamoTx @jadafo Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells stm.sciencemag.org/content/12/557…
TregCell Radar retweeted
Authors in this #EditorsChoice article believe their study identifies #Treg cell as a promising target for treating #ChronicMigraine. Read the full article with a supplemental video in #PAINJournal: bit.ly/2Mpq8TN
TregCell Radar retweeted
Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function | Science Translational Medicine stm.sciencemag.org/content/12/546…
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